Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased ras signaling

Molecular and Cellular Biology

Volumn 30, Issue 19, 2010, Pages 4698-4711

  Molzan, Manuela ^a   Schumacher, Benjamin ^a   Ottmann, Corinna ^b   Baljuls, Angela ^c   Polzien, Lisa ^c   Weyand, Michael ^a   Thiel, Philipp ^a   Rose, Rolf ^a   Rose, Micheline ^a   Kuhenne, Philipp ^a   Kaiser, Markus ^a   Rapp, Ulf R ^c   Kuhlmann, Jürgen ^b   Ottmann, Christian ^a  

^a CHEMICAL GENOMICS CENTRE OF THE MAX PLANCK SOCIETY   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN 14 3 3; RAF PROTEIN; RAS PROTEIN;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; NOONAN SYNDROME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

14-3-3 PROTEINS; ANIMALS; BINDING SITES; CELL LINE; CERCOPITHECUS AETHIOPS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; GREEN FLUORESCENT PROTEINS; HUMANS; KINETICS; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; MUTATION; NOONAN SYNDROME; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-RAF; RAS PROTEINS; SERINE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 77956687588     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01636-09     Document Type: Article

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