메뉴 건너뛰기




Volumn 10, Issue 5, 2010, Pages 594-600

Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness)

Author keywords

[No Author keywords available]

Indexed keywords

ANXIETY; BIPOLAR DISORDER; CIRCADIAN RHYTHM; DISEASE MODEL; DRUG RESEARCH; ENVIRONMENTAL FACTOR; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOMICS; HUMAN; HUMAN GENETICS; IRRITABILITY; MENTAL STRESS; MOOD DISORDER; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; REPRODUCIBILITY; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SYMPTOMATOLOGY;

EID: 77956650793     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2010.08.008     Document Type: Review
Times cited : (11)

References (51)
  • 1
    • 72049106429 scopus 로고    scopus 로고
    • Convergent Functional Genomics: what we have learned and can learn about genes, pathways, and mechanisms
    • Niculescu A.B., Le-Niculescu H. Convergent Functional Genomics: what we have learned and can learn about genes, pathways, and mechanisms. Neuropsychopharmacology 2010, 35:355-356.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 355-356
    • Niculescu, A.B.1    Le-Niculescu, H.2
  • 2
    • 33748932875 scopus 로고    scopus 로고
    • PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypes
    • Niculescu A.B., et al. PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypes. Am J Med Genet B Neuropsychiatr Genet 2006, 141:653-662.
    • (2006) Am J Med Genet B Neuropsychiatr Genet , vol.141 , pp. 653-662
    • Niculescu, A.B.1
  • 3
    • 33751038854 scopus 로고    scopus 로고
    • Polypharmacy in oligopopulations: what psychiatric genetics can teach biological psychiatry
    • Niculescu A.B. Polypharmacy in oligopopulations: what psychiatric genetics can teach biological psychiatry. Psychiatr Genet 2006, 16:241-244.
    • (2006) Psychiatr Genet , vol.16 , pp. 241-244
    • Niculescu, A.B.1
  • 4
    • 55849150017 scopus 로고    scopus 로고
    • The emergence of the bipolar spectrum: validation along clinical-epidemiologic and familial-genetic lines
    • Akiskal H.S. The emergence of the bipolar spectrum: validation along clinical-epidemiologic and familial-genetic lines. Psychopharmacol Bull 2007, 40:99-115.
    • (2007) Psychopharmacol Bull , vol.40 , pp. 99-115
    • Akiskal, H.S.1
  • 5
    • 77952101503 scopus 로고    scopus 로고
    • Mindscape: a convergent perspective on life, mind, consciousness and happiness
    • Niculescu A.B., Schork N.J., Salomon D.R. Mindscape: a convergent perspective on life, mind, consciousness and happiness. J Affect Disord 2010, 123:1-8.
    • (2010) J Affect Disord , vol.123 , pp. 1-8
    • Niculescu, A.B.1    Schork, N.J.2    Salomon, D.R.3
  • 6
    • 0347710163 scopus 로고    scopus 로고
    • Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach
    • Niculescu A.B., et al. Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach. Physiol Genomics 2000, 4:83-91.
    • (2000) Physiol Genomics , vol.4 , pp. 83-91
    • Niculescu, A.B.1
  • 7
    • 67349155577 scopus 로고    scopus 로고
    • The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers
    • Kelly M.P., et al. The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers. Pharmacol Biochem Behav 2009, 92:649-654.
    • (2009) Pharmacol Biochem Behav , vol.92 , pp. 649-654
    • Kelly, M.P.1
  • 8
    • 8744303553 scopus 로고    scopus 로고
    • Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach
    • Ogden C.A., et al. Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Mol Psychiatry 2004, 9:1007-1029.
    • (2004) Mol Psychiatry , vol.9 , pp. 1007-1029
    • Ogden, C.A.1
  • 9
    • 58549118937 scopus 로고    scopus 로고
    • Identifying blood biomarkers for mood disorders using convergent functional genomics
    • Le-Niculescu H., et al. Identifying blood biomarkers for mood disorders using convergent functional genomics. Mol Psychiatry 2009, 14:156-174.
    • (2009) Mol Psychiatry , vol.14 , pp. 156-174
    • Le-Niculescu, H.1
  • 10
    • 40449122600 scopus 로고    scopus 로고
    • Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism
    • Le-Niculescu H., et al. Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism. Am J Med Genet B 2008, 147B:134-166.
    • (2008) Am J Med Genet B , vol.147 B , pp. 134-166
    • Le-Niculescu, H.1
  • 11
    • 34547498395 scopus 로고    scopus 로고
    • From the Cover: mania-like behavior induced by disruption of CLOCK
    • Roybal K, et al. From the Cover: mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci USA 2007, 104:6406-6411.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 6406-6411
    • Roybal, K.1
  • 12
    • 77956101152 scopus 로고    scopus 로고
    • Knockdown of clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior
    • Mukherjee S., et al. Knockdown of clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior. Biol Psychiatry 2010.
    • (2010) Biol Psychiatry
    • Mukherjee, S.1
  • 13
    • 77953285045 scopus 로고    scopus 로고
    • The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration
    • Young J.W., et al. The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration. Pharmacol Biochem Behav 2010, 96:7-15.
    • (2010) Pharmacol Biochem Behav , vol.96 , pp. 7-15
    • Young, J.W.1
  • 14
    • 71349083888 scopus 로고    scopus 로고
    • Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour
    • Taniguchi S., et al. Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. EMBO J 2009, 28:3717-3729.
    • (2009) EMBO J , vol.28 , pp. 3717-3729
    • Taniguchi, S.1
  • 15
    • 71049143223 scopus 로고    scopus 로고
    • Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level
    • Barbier E., Wang J.B. Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level. BMC Neurosci 2009, 10:132.
    • (2009) BMC Neurosci , vol.10 , pp. 132
    • Barbier, E.1    Wang, J.B.2
  • 16
    • 62849084624 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement
    • Engel S.R., et al. The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement. Mol Psychiatry 2009, 14:448-461.
    • (2009) Mol Psychiatry , vol.14 , pp. 448-461
    • Engel, S.R.1
  • 17
    • 49949086234 scopus 로고    scopus 로고
    • Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania
    • Shaltiel G., et al. Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry 2008, 13:858-872.
    • (2008) Mol Psychiatry , vol.13 , pp. 858-872
    • Shaltiel, G.1
  • 18
    • 77950369626 scopus 로고    scopus 로고
    • The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents
    • Malkesman O., et al. The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents. Biol Psychiatry 2010, 67:864-871.
    • (2010) Biol Psychiatry , vol.67 , pp. 864-871
    • Malkesman, O.1
  • 19
    • 33745712834 scopus 로고    scopus 로고
    • Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes
    • 577-593, 523
    • Kasahara T., et al. Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes. Mol Psychiatry 2006, 11. 577-593, 523.
    • (2006) Mol Psychiatry , vol.11
    • Kasahara, T.1
  • 20
    • 79952666146 scopus 로고    scopus 로고
    • Therapeutic implications of down-regulation of cyclophilin D in bipolar disorder
    • Kubota M., et al. Therapeutic implications of down-regulation of cyclophilin D in bipolar disorder. Int J Neuropsychopharmacol 2010, 1-14.
    • (2010) Int J Neuropsychopharmacol , pp. 1-14
    • Kubota, M.1
  • 21
    • 38349128462 scopus 로고    scopus 로고
    • A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
    • Baum A.E., et al. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry 2008, 13:197-207.
    • (2008) Mol Psychiatry , vol.13 , pp. 197-207
    • Baum, A.E.1
  • 22
    • 43949118134 scopus 로고    scopus 로고
    • Whole-genome association study of bipolar disorder
    • Sklar P., et al. Whole-genome association study of bipolar disorder. Mol Psychiatry 2008, 13:558-569.
    • (2008) Mol Psychiatry , vol.13 , pp. 558-569
    • Sklar, P.1
  • 23
    • 67651158803 scopus 로고    scopus 로고
    • Genome-wide association study of bipolar disorder in European American and African American individuals
    • Smith E.N., et al. Genome-wide association study of bipolar disorder in European American and African American individuals. Mol Psychiatry 2009, 14:755-763.
    • (2009) Mol Psychiatry , vol.14 , pp. 755-763
    • Smith, E.N.1
  • 24
    • 66149092770 scopus 로고    scopus 로고
    • Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry
    • Scott L.J., et al. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc Natl Acad Sci USA 2009, 106:7501-7506.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7501-7506
    • Scott, L.J.1
  • 25
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447:661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 26
    • 34247367138 scopus 로고    scopus 로고
    • Increase in GSK3beta gene copy number variation in bipolar disorder
    • Lachman H.M., et al. Increase in GSK3beta gene copy number variation in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 2007, 144B:259-265.
    • (2007) Am J Med Genet B Neuropsychiatr Genet , vol.144 B , pp. 259-265
    • Lachman, H.M.1
  • 27
    • 62849092230 scopus 로고    scopus 로고
    • Singleton deletions throughout the genome increase risk of bipolar disorder
    • Zhang D., et al. Singleton deletions throughout the genome increase risk of bipolar disorder. Mol Psychiatry 2009, 14:376-380.
    • (2009) Mol Psychiatry , vol.14 , pp. 376-380
    • Zhang, D.1
  • 28
    • 50449089356 scopus 로고    scopus 로고
    • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
    • Ferreira M.A., et al. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 2008, 40:1056-1058.
    • (2008) Nat Genet , vol.40 , pp. 1056-1058
    • Ferreira, M.A.1
  • 29
    • 67349153674 scopus 로고    scopus 로고
    • Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder
    • Schulze T.G., et al. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol Psychiatry 2009, 14:487-491.
    • (2009) Mol Psychiatry , vol.14 , pp. 487-491
    • Schulze, T.G.1
  • 30
    • 78650511487 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder
    • Liu Y., et al. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Mol Psychiatry 2010.
    • (2010) Mol Psychiatry
    • Liu, Y.1
  • 31
    • 77955956142 scopus 로고    scopus 로고
    • Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder
    • Williams H.J., et al. Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry 2010.
    • (2010) Mol Psychiatry
    • Williams, H.J.1
  • 33
    • 61449223631 scopus 로고    scopus 로고
    • Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms
    • Le-Niculescu H., et al. Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet 2009, 150B:155-181.
    • (2009) Am J Med Genet B Neuropsychiatr Genet , vol.150 B , pp. 155-181
    • Le-Niculescu, H.1
  • 34
    • 77952735731 scopus 로고    scopus 로고
    • Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics
    • Patel S.D, et al. Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics. Am J Med Genet B Neuropsychiatr Genet 2010, 153B:850-877.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 B , pp. 850-877
    • Patel, S.D.1
  • 35
    • 71049158829 scopus 로고    scopus 로고
    • Evidence for genetic association of RORB with bipolar disorder
    • McGrath C.L., et al. Evidence for genetic association of RORB with bipolar disorder. BMC Psychiatry 2009, 9:70.
    • (2009) BMC Psychiatry , vol.9 , pp. 70
    • McGrath, C.L.1
  • 36
    • 27844556870 scopus 로고    scopus 로고
    • Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders
    • Bertsch B., et al. Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders. Methods 2005, 37:274-279.
    • (2005) Methods , vol.37 , pp. 274-279
    • Bertsch, B.1
  • 38
    • 74149085505 scopus 로고    scopus 로고
    • It is darkness and not light: depression-like behaviors of diurnal unstriped Nile grass rats maintained under a short photoperiod schedule
    • Ashkenazy-Frolinger T., Kronfeld-Schor N., Juetten J., Einat H. It is darkness and not light: depression-like behaviors of diurnal unstriped Nile grass rats maintained under a short photoperiod schedule. J Neurosci Methods 2010, 186:165-170.
    • (2010) J Neurosci Methods , vol.186 , pp. 165-170
    • Ashkenazy-Frolinger, T.1    Kronfeld-Schor, N.2    Juetten, J.3    Einat, H.4
  • 39
    • 77950909228 scopus 로고    scopus 로고
    • Possible involvement of signal transducers and activators of transcription 3 system on depression in the model mice brain
    • Mingmalairak S., Tohda M., Murakami Y., Matsumoto K. Possible involvement of signal transducers and activators of transcription 3 system on depression in the model mice brain. Biol Pharm Bull 2010, 33:636-640.
    • (2010) Biol Pharm Bull , vol.33 , pp. 636-640
    • Mingmalairak, S.1    Tohda, M.2    Murakami, Y.3    Matsumoto, K.4
  • 40
    • 67349112146 scopus 로고    scopus 로고
    • Two different putative genetic animal models of childhood depression-a review
    • Malkesman O., Weller A. Two different putative genetic animal models of childhood depression-a review. Prog Neurobiol 2009, 88:153-169.
    • (2009) Prog Neurobiol , vol.88 , pp. 153-169
    • Malkesman, O.1    Weller, A.2
  • 41
    • 40849094032 scopus 로고    scopus 로고
    • Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice
    • Gould T.D., et al. Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice. Behav Brain Res 2008, 189:117-125.
    • (2008) Behav Brain Res , vol.189 , pp. 117-125
    • Gould, T.D.1
  • 42
    • 0242469018 scopus 로고    scopus 로고
    • Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressants
    • Will C.C., Aird F., Redei E.E. Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressants. Mol Psychiatry 2003, 8:925-932.
    • (2003) Mol Psychiatry , vol.8 , pp. 925-932
    • Will, C.C.1    Aird, F.2    Redei, E.E.3
  • 43
    • 34249087808 scopus 로고    scopus 로고
    • Strain differences in lithium attenuation of d-amphetamine-induced hyperlocomotion: a mouse model for the genetics of clinical response to lithium
    • Gould T.D., O'Donnell K.C., Picchini A.M., Manji H.K. Strain differences in lithium attenuation of d-amphetamine-induced hyperlocomotion: a mouse model for the genetics of clinical response to lithium. Neuropsychopharmacology 2007, 32:1321-1333.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1321-1333
    • Gould, T.D.1    O'Donnell, K.C.2    Picchini, A.M.3    Manji, H.K.4
  • 44
    • 71849114932 scopus 로고    scopus 로고
    • Shock-induced aggression in mice is modified by lithium
    • Kovacsics C.E., Gould T.D. Shock-induced aggression in mice is modified by lithium. Pharmacol Biochem Behav 2010, 94:380-386.
    • (2010) Pharmacol Biochem Behav , vol.94 , pp. 380-386
    • Kovacsics, C.E.1    Gould, T.D.2
  • 45
    • 68349154620 scopus 로고    scopus 로고
    • Lithium treatment prevents stress-induced dendritic remodeling in the rodent amygdala
    • Johnson S.A., et al. Lithium treatment prevents stress-induced dendritic remodeling in the rodent amygdala. Neuroscience 2009, 163:34-39.
    • (2009) Neuroscience , vol.163 , pp. 34-39
    • Johnson, S.A.1
  • 46
    • 77955069785 scopus 로고    scopus 로고
    • The mood stabilizer lamotrigine produces antidepressant behavioral effects in rats: role of brain-derived neurotrophic factor
    • Li N., He X., Qi X., Zhang Y., He S. The mood stabilizer lamotrigine produces antidepressant behavioral effects in rats: role of brain-derived neurotrophic factor. J Psychopharmacol 2010.
    • (2010) J Psychopharmacol
    • Li, N.1    He, X.2    Qi, X.3    Zhang, Y.4    He, S.5
  • 47
    • 70349776041 scopus 로고    scopus 로고
    • Topiramate and phenytoin anti-immobility effect in the mice forced swimming test is reversed by veratrine: implication for bipolar depression treatment
    • Bourin M., Chenu F., Hascoet M. Topiramate and phenytoin anti-immobility effect in the mice forced swimming test is reversed by veratrine: implication for bipolar depression treatment. Behav Brain Res 2009, 205:421-425.
    • (2009) Behav Brain Res , vol.205 , pp. 421-425
    • Bourin, M.1    Chenu, F.2    Hascoet, M.3
  • 48
    • 77249129746 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior
    • Koo J.W., Russo S.J., Ferguson D., Nestler E.J., Duman R.S. Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proc Natl Acad Sci USA 2010, 107:2669-2674.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2669-2674
    • Koo, J.W.1    Russo, S.J.2    Ferguson, D.3    Nestler, E.J.4    Duman, R.S.5
  • 49
    • 34548046690 scopus 로고    scopus 로고
    • Mimicking human bipolar ion dysregulation models mania in rats
    • Herman L., Hougland T., El-Mallakh R.S. Mimicking human bipolar ion dysregulation models mania in rats. Neurosci Biobehav Rev 2007, 31:874-881.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 874-881
    • Herman, L.1    Hougland, T.2    El-Mallakh, R.S.3
  • 50
    • 42749091325 scopus 로고    scopus 로고
    • Behavioral and gene expression analyses of Wfs1 knockout mice as a possible animal model of mood disorder
    • Kato T., et al. Behavioral and gene expression analyses of Wfs1 knockout mice as a possible animal model of mood disorder. Neurosci Res 2008, 61:143-158.
    • (2008) Neurosci Res , vol.61 , pp. 143-158
    • Kato, T.1
  • 51
    • 77649238766 scopus 로고    scopus 로고
    • GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior
    • Young J.W., et al. GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior. Psychopharmacology (Berl) 2010, 208:443-454.
    • (2010) Psychopharmacology (Berl) , vol.208 , pp. 443-454
    • Young, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.