-
1
-
-
72049106429
-
Convergent Functional Genomics: what we have learned and can learn about genes, pathways, and mechanisms
-
Niculescu A.B., Le-Niculescu H. Convergent Functional Genomics: what we have learned and can learn about genes, pathways, and mechanisms. Neuropsychopharmacology 2010, 35:355-356.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 355-356
-
-
Niculescu, A.B.1
Le-Niculescu, H.2
-
2
-
-
33748932875
-
PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypes
-
Niculescu A.B., et al. PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypes. Am J Med Genet B Neuropsychiatr Genet 2006, 141:653-662.
-
(2006)
Am J Med Genet B Neuropsychiatr Genet
, vol.141
, pp. 653-662
-
-
Niculescu, A.B.1
-
3
-
-
33751038854
-
Polypharmacy in oligopopulations: what psychiatric genetics can teach biological psychiatry
-
Niculescu A.B. Polypharmacy in oligopopulations: what psychiatric genetics can teach biological psychiatry. Psychiatr Genet 2006, 16:241-244.
-
(2006)
Psychiatr Genet
, vol.16
, pp. 241-244
-
-
Niculescu, A.B.1
-
4
-
-
55849150017
-
The emergence of the bipolar spectrum: validation along clinical-epidemiologic and familial-genetic lines
-
Akiskal H.S. The emergence of the bipolar spectrum: validation along clinical-epidemiologic and familial-genetic lines. Psychopharmacol Bull 2007, 40:99-115.
-
(2007)
Psychopharmacol Bull
, vol.40
, pp. 99-115
-
-
Akiskal, H.S.1
-
5
-
-
77952101503
-
Mindscape: a convergent perspective on life, mind, consciousness and happiness
-
Niculescu A.B., Schork N.J., Salomon D.R. Mindscape: a convergent perspective on life, mind, consciousness and happiness. J Affect Disord 2010, 123:1-8.
-
(2010)
J Affect Disord
, vol.123
, pp. 1-8
-
-
Niculescu, A.B.1
Schork, N.J.2
Salomon, D.R.3
-
6
-
-
0347710163
-
Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach
-
Niculescu A.B., et al. Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach. Physiol Genomics 2000, 4:83-91.
-
(2000)
Physiol Genomics
, vol.4
, pp. 83-91
-
-
Niculescu, A.B.1
-
7
-
-
67349155577
-
The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers
-
Kelly M.P., et al. The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers. Pharmacol Biochem Behav 2009, 92:649-654.
-
(2009)
Pharmacol Biochem Behav
, vol.92
, pp. 649-654
-
-
Kelly, M.P.1
-
8
-
-
8744303553
-
Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach
-
Ogden C.A., et al. Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Mol Psychiatry 2004, 9:1007-1029.
-
(2004)
Mol Psychiatry
, vol.9
, pp. 1007-1029
-
-
Ogden, C.A.1
-
9
-
-
58549118937
-
Identifying blood biomarkers for mood disorders using convergent functional genomics
-
Le-Niculescu H., et al. Identifying blood biomarkers for mood disorders using convergent functional genomics. Mol Psychiatry 2009, 14:156-174.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 156-174
-
-
Le-Niculescu, H.1
-
10
-
-
40449122600
-
Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism
-
Le-Niculescu H., et al. Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism. Am J Med Genet B 2008, 147B:134-166.
-
(2008)
Am J Med Genet B
, vol.147 B
, pp. 134-166
-
-
Le-Niculescu, H.1
-
11
-
-
34547498395
-
From the Cover: mania-like behavior induced by disruption of CLOCK
-
Roybal K, et al. From the Cover: mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci USA 2007, 104:6406-6411.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 6406-6411
-
-
Roybal, K.1
-
12
-
-
77956101152
-
Knockdown of clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior
-
Mukherjee S., et al. Knockdown of clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior. Biol Psychiatry 2010.
-
(2010)
Biol Psychiatry
-
-
Mukherjee, S.1
-
13
-
-
77953285045
-
The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration
-
Young J.W., et al. The mania-like exploratory profile in genetic dopamine transporter mouse models is diminished in a familiar environment and reinstated by subthreshold psychostimulant administration. Pharmacol Biochem Behav 2010, 96:7-15.
-
(2010)
Pharmacol Biochem Behav
, vol.96
, pp. 7-15
-
-
Young, J.W.1
-
14
-
-
71349083888
-
Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour
-
Taniguchi S., et al. Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. EMBO J 2009, 28:3717-3729.
-
(2009)
EMBO J
, vol.28
, pp. 3717-3729
-
-
Taniguchi, S.1
-
15
-
-
71049143223
-
Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level
-
Barbier E., Wang J.B. Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level. BMC Neurosci 2009, 10:132.
-
(2009)
BMC Neurosci
, vol.10
, pp. 132
-
-
Barbier, E.1
Wang, J.B.2
-
16
-
-
62849084624
-
The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement
-
Engel S.R., et al. The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement. Mol Psychiatry 2009, 14:448-461.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 448-461
-
-
Engel, S.R.1
-
17
-
-
49949086234
-
Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania
-
Shaltiel G., et al. Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry 2008, 13:858-872.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 858-872
-
-
Shaltiel, G.1
-
18
-
-
77950369626
-
The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents
-
Malkesman O., et al. The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents. Biol Psychiatry 2010, 67:864-871.
-
(2010)
Biol Psychiatry
, vol.67
, pp. 864-871
-
-
Malkesman, O.1
-
19
-
-
33745712834
-
Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes
-
577-593, 523
-
Kasahara T., et al. Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes. Mol Psychiatry 2006, 11. 577-593, 523.
-
(2006)
Mol Psychiatry
, vol.11
-
-
Kasahara, T.1
-
20
-
-
79952666146
-
Therapeutic implications of down-regulation of cyclophilin D in bipolar disorder
-
Kubota M., et al. Therapeutic implications of down-regulation of cyclophilin D in bipolar disorder. Int J Neuropsychopharmacol 2010, 1-14.
-
(2010)
Int J Neuropsychopharmacol
, pp. 1-14
-
-
Kubota, M.1
-
21
-
-
38349128462
-
A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
-
Baum A.E., et al. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry 2008, 13:197-207.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 197-207
-
-
Baum, A.E.1
-
22
-
-
43949118134
-
Whole-genome association study of bipolar disorder
-
Sklar P., et al. Whole-genome association study of bipolar disorder. Mol Psychiatry 2008, 13:558-569.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 558-569
-
-
Sklar, P.1
-
23
-
-
67651158803
-
Genome-wide association study of bipolar disorder in European American and African American individuals
-
Smith E.N., et al. Genome-wide association study of bipolar disorder in European American and African American individuals. Mol Psychiatry 2009, 14:755-763.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 755-763
-
-
Smith, E.N.1
-
24
-
-
66149092770
-
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry
-
Scott L.J., et al. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc Natl Acad Sci USA 2009, 106:7501-7506.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7501-7506
-
-
Scott, L.J.1
-
25
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
26
-
-
34247367138
-
Increase in GSK3beta gene copy number variation in bipolar disorder
-
Lachman H.M., et al. Increase in GSK3beta gene copy number variation in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 2007, 144B:259-265.
-
(2007)
Am J Med Genet B Neuropsychiatr Genet
, vol.144 B
, pp. 259-265
-
-
Lachman, H.M.1
-
27
-
-
62849092230
-
Singleton deletions throughout the genome increase risk of bipolar disorder
-
Zhang D., et al. Singleton deletions throughout the genome increase risk of bipolar disorder. Mol Psychiatry 2009, 14:376-380.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 376-380
-
-
Zhang, D.1
-
28
-
-
50449089356
-
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
-
Ferreira M.A., et al. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 2008, 40:1056-1058.
-
(2008)
Nat Genet
, vol.40
, pp. 1056-1058
-
-
Ferreira, M.A.1
-
29
-
-
67349153674
-
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder
-
Schulze T.G., et al. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol Psychiatry 2009, 14:487-491.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 487-491
-
-
Schulze, T.G.1
-
30
-
-
78650511487
-
Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder
-
Liu Y., et al. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Mol Psychiatry 2010.
-
(2010)
Mol Psychiatry
-
-
Liu, Y.1
-
31
-
-
77955956142
-
Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder
-
Williams H.J., et al. Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry 2010.
-
(2010)
Mol Psychiatry
-
-
Williams, H.J.1
-
33
-
-
61449223631
-
Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms
-
Le-Niculescu H., et al. Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet 2009, 150B:155-181.
-
(2009)
Am J Med Genet B Neuropsychiatr Genet
, vol.150 B
, pp. 155-181
-
-
Le-Niculescu, H.1
-
34
-
-
77952735731
-
Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics
-
Patel S.D, et al. Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics. Am J Med Genet B Neuropsychiatr Genet 2010, 153B:850-877.
-
(2010)
Am J Med Genet B Neuropsychiatr Genet
, vol.153 B
, pp. 850-877
-
-
Patel, S.D.1
-
35
-
-
71049158829
-
Evidence for genetic association of RORB with bipolar disorder
-
McGrath C.L., et al. Evidence for genetic association of RORB with bipolar disorder. BMC Psychiatry 2009, 9:70.
-
(2009)
BMC Psychiatry
, vol.9
, pp. 70
-
-
McGrath, C.L.1
-
36
-
-
27844556870
-
Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders
-
Bertsch B., et al. Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders. Methods 2005, 37:274-279.
-
(2005)
Methods
, vol.37
, pp. 274-279
-
-
Bertsch, B.1
-
37
-
-
77954848215
-
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
-
Marcheva B., Ramsey K.M., Buhr E.D., Kobayashi Y., Su H., Ko C.H., Ivanova G., Omura C., Mo S., Vitaterna M.H., et al. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature 2010, 466:627-631.
-
(2010)
Nature
, vol.466
, pp. 627-631
-
-
Marcheva, B.1
Ramsey, K.M.2
Buhr, E.D.3
Kobayashi, Y.4
Su, H.5
Ko, C.H.6
Ivanova, G.7
Omura, C.8
Mo, S.9
Vitaterna, M.H.10
-
38
-
-
74149085505
-
It is darkness and not light: depression-like behaviors of diurnal unstriped Nile grass rats maintained under a short photoperiod schedule
-
Ashkenazy-Frolinger T., Kronfeld-Schor N., Juetten J., Einat H. It is darkness and not light: depression-like behaviors of diurnal unstriped Nile grass rats maintained under a short photoperiod schedule. J Neurosci Methods 2010, 186:165-170.
-
(2010)
J Neurosci Methods
, vol.186
, pp. 165-170
-
-
Ashkenazy-Frolinger, T.1
Kronfeld-Schor, N.2
Juetten, J.3
Einat, H.4
-
39
-
-
77950909228
-
Possible involvement of signal transducers and activators of transcription 3 system on depression in the model mice brain
-
Mingmalairak S., Tohda M., Murakami Y., Matsumoto K. Possible involvement of signal transducers and activators of transcription 3 system on depression in the model mice brain. Biol Pharm Bull 2010, 33:636-640.
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 636-640
-
-
Mingmalairak, S.1
Tohda, M.2
Murakami, Y.3
Matsumoto, K.4
-
40
-
-
67349112146
-
Two different putative genetic animal models of childhood depression-a review
-
Malkesman O., Weller A. Two different putative genetic animal models of childhood depression-a review. Prog Neurobiol 2009, 88:153-169.
-
(2009)
Prog Neurobiol
, vol.88
, pp. 153-169
-
-
Malkesman, O.1
Weller, A.2
-
41
-
-
40849094032
-
Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice
-
Gould T.D., et al. Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice. Behav Brain Res 2008, 189:117-125.
-
(2008)
Behav Brain Res
, vol.189
, pp. 117-125
-
-
Gould, T.D.1
-
42
-
-
0242469018
-
Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressants
-
Will C.C., Aird F., Redei E.E. Selectively bred Wistar-Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressants. Mol Psychiatry 2003, 8:925-932.
-
(2003)
Mol Psychiatry
, vol.8
, pp. 925-932
-
-
Will, C.C.1
Aird, F.2
Redei, E.E.3
-
43
-
-
34249087808
-
Strain differences in lithium attenuation of d-amphetamine-induced hyperlocomotion: a mouse model for the genetics of clinical response to lithium
-
Gould T.D., O'Donnell K.C., Picchini A.M., Manji H.K. Strain differences in lithium attenuation of d-amphetamine-induced hyperlocomotion: a mouse model for the genetics of clinical response to lithium. Neuropsychopharmacology 2007, 32:1321-1333.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 1321-1333
-
-
Gould, T.D.1
O'Donnell, K.C.2
Picchini, A.M.3
Manji, H.K.4
-
44
-
-
71849114932
-
Shock-induced aggression in mice is modified by lithium
-
Kovacsics C.E., Gould T.D. Shock-induced aggression in mice is modified by lithium. Pharmacol Biochem Behav 2010, 94:380-386.
-
(2010)
Pharmacol Biochem Behav
, vol.94
, pp. 380-386
-
-
Kovacsics, C.E.1
Gould, T.D.2
-
45
-
-
68349154620
-
Lithium treatment prevents stress-induced dendritic remodeling in the rodent amygdala
-
Johnson S.A., et al. Lithium treatment prevents stress-induced dendritic remodeling in the rodent amygdala. Neuroscience 2009, 163:34-39.
-
(2009)
Neuroscience
, vol.163
, pp. 34-39
-
-
Johnson, S.A.1
-
46
-
-
77955069785
-
The mood stabilizer lamotrigine produces antidepressant behavioral effects in rats: role of brain-derived neurotrophic factor
-
Li N., He X., Qi X., Zhang Y., He S. The mood stabilizer lamotrigine produces antidepressant behavioral effects in rats: role of brain-derived neurotrophic factor. J Psychopharmacol 2010.
-
(2010)
J Psychopharmacol
-
-
Li, N.1
He, X.2
Qi, X.3
Zhang, Y.4
He, S.5
-
47
-
-
70349776041
-
Topiramate and phenytoin anti-immobility effect in the mice forced swimming test is reversed by veratrine: implication for bipolar depression treatment
-
Bourin M., Chenu F., Hascoet M. Topiramate and phenytoin anti-immobility effect in the mice forced swimming test is reversed by veratrine: implication for bipolar depression treatment. Behav Brain Res 2009, 205:421-425.
-
(2009)
Behav Brain Res
, vol.205
, pp. 421-425
-
-
Bourin, M.1
Chenu, F.2
Hascoet, M.3
-
48
-
-
77249129746
-
Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior
-
Koo J.W., Russo S.J., Ferguson D., Nestler E.J., Duman R.S. Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proc Natl Acad Sci USA 2010, 107:2669-2674.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2669-2674
-
-
Koo, J.W.1
Russo, S.J.2
Ferguson, D.3
Nestler, E.J.4
Duman, R.S.5
-
49
-
-
34548046690
-
Mimicking human bipolar ion dysregulation models mania in rats
-
Herman L., Hougland T., El-Mallakh R.S. Mimicking human bipolar ion dysregulation models mania in rats. Neurosci Biobehav Rev 2007, 31:874-881.
-
(2007)
Neurosci Biobehav Rev
, vol.31
, pp. 874-881
-
-
Herman, L.1
Hougland, T.2
El-Mallakh, R.S.3
-
50
-
-
42749091325
-
Behavioral and gene expression analyses of Wfs1 knockout mice as a possible animal model of mood disorder
-
Kato T., et al. Behavioral and gene expression analyses of Wfs1 knockout mice as a possible animal model of mood disorder. Neurosci Res 2008, 61:143-158.
-
(2008)
Neurosci Res
, vol.61
, pp. 143-158
-
-
Kato, T.1
-
51
-
-
77649238766
-
GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior
-
Young J.W., et al. GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior. Psychopharmacology (Berl) 2010, 208:443-454.
-
(2010)
Psychopharmacology (Berl)
, vol.208
, pp. 443-454
-
-
Young, J.W.1
|