Chain-dependent photocytotoxicity of tricationic porphyrin conjugates and related mechanisms of cell death in proliferating human skin keratinocytes

Biochemical Pharmacology

Volumn 80, Issue 9, 2010, Pages 1373-1385

  Silva, João Nuno ^a,b,c,d   Galmiche, Antoine ^b,c,d   Tomé, João P C ^e   Boullier, Agnès ^b,c,d   Neves, Maria G P M S ^e   Silva, Eduarda M P ^e   Capiod, Jean Claude ^d   Cavaleiro, José A S ^e   Santus, René ^f   Mazière, Jean Claude ^b,c,d   Filipe, Paulo ^a   Morlière, Patrice ^b,c,d  

^a HOSPITAL DE SANTA MARIA   (Portugal)

^b INSERM   (France)

^c UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^d AMIENS UNIVERSITY HOSPITAL   (France)

^e UNIVERSITY OF AVEIRO   (Portugal)

^f MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

Autophagy; Caspases; MAPK pathway; Necrosis; PDT; Photocytotoxicity

Indexed keywords

ALPHA BETA DEXTRO GALACTOPYRANOSYL; BETA DEXTRO GALACTOPYRANOSYL; CASPASE; DI O ISOPROPYLIDENE GALACTOPYRANOSYL; GREEN FLUORESCENT PROTEIN; LIPOCORTIN 5; METHYL GROUP; MITOGEN ACTIVATED PROTEIN KINASE 1; N,N' DICYCLOHEXYLUREIDOOXYCARBONYL; POLYLYSINE; PORPHYRIN DERIVATIVE; PROTOPORPHYRIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE; PORPHYRIN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL PROLIFERATION; CHROMATIN CONDENSATION; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; ENDOCYTOSIS; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; KERATINOCYTE; MICROFLUOROMETRY; OXIDATIVE STRESS; PHOTOTOXICITY; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; CELL CULTURE; DRUG EFFECTS; METABOLISM; PHOTOCHEMOTHERAPY; PHYSIOLOGY;

ANNEXIN A5; APOPTOSIS; AUTOPHAGY; CASPASES; CELLS, CULTURED; HUMANS; KERATINOCYTES; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PHOTOCHEMOTHERAPY; PORPHYRINS;

EID: 77956650379     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.07.033     Document Type: Article

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