Suboptimal vitamin K status despite supplementation in children and young adults with cystic fibrosis

American Journal of Clinical Nutrition

Volumn 92, Issue 3, 2010, Pages 660-667

  Dougherty, Kelly A ^a   Schall, Joan I ^a   Stallings, Virginia A ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; DECARBOXYPROTHROMBIN; OSTEOCALCIN; PHYTOMENADIONE; PLASMA PROTEIN; PROTHROMBIN; VITAMIN K GROUP; 25-HYDROXYVITAMIN D; DRUG DERIVATIVE; VITAMIN; VITAMIN D;

ADOLESCENT; ADULT; ANTHROPOMETRY; ARTICLE; BODY COMPOSITION; CHILD; CONTROLLED STUDY; CYSTIC FIBROSIS; DIETARY INTAKE; FEMALE; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRESCHOOL CHILD; SCHOOL CHILD; SEX DIFFERENCE; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; BLOOD; CASE CONTROL STUDY; DIET SUPPLEMENTATION; METABOLISM; NUTRITIONAL STATUS; PANCREAS DISEASE; VITAMIN K DEFICIENCY;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CYSTIC FIBROSIS; DIETARY SUPPLEMENTS; FEMALE; HUMANS; MALE; NUTRITIONAL STATUS; OSTEOCALCIN; PANCREATIC DISEASES; PROTHROMBIN; SEX FACTORS; VITAMIN D; VITAMIN K; VITAMIN K DEFICIENCY; VITAMINS; YOUNG ADULT;

EID: 77956642628     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.2010.29350     Document Type: Article

References (36)

1. Booth SL. Roles for vitamin K beyond coagulation. Annu Rev Nutr 2009;29:89-110.
2. Rashid M, Durie P, Andrew M, et al. Prevalence of vitamin K deficiency in cystic fibrosis. Am J Clin Nutr 1999;70:378-82. (Pubitemid 29407158)
3. Conway SP, Wolfe SP, Brownlee KG, et al. Vitamin K status among children with cystic fibrosis and its relationship to bone mineral density and bone turnover. Pediatrics 2005;115:1325-31.
4. Ramsey BW, Farrell PM, Pencharz P. Nutritional assessment and management in cystic fibrosis: a consensus report. The Consensus Committee. Am J Clin Nutr 1992;55:108-16.
5. Shearer MJ. Vitamin K. Lancet 1995;345:229-34.
6. Borowitz D, Baker RD, Stallings V. Consensus report on nutrition for pediatric patients with cystic fibrosis. J Pediatr Gastroenterol Nutr 2002;35:246-59.
7. Beker LT, Ahrens RA, Fink RJ, et al. Effect of vitamin K1 supplementation on vitamin K status in cystic fibrosis patients. J Pediatr Gastroenterol Nutr 1997;24:512-7.
8. Wilson DC, Rashid M, Durie PR, et al. Treatment of vitamin K deficiency in cystic fibrosis: Effectiveness of a daily fat-soluble vitamin combination. J Pediatr 2001;138:851-5. (Pubitemid 32545586)
9. Grey V, Atkinson S, Drury D, et al. Prevalence of low bone mass and deficiencies of vitamins D and K in pediatric patients with cystic fibrosis from 3 Canadian centers. Pediatrics 2008;122:1014-20.
10. Drury D, Grey VL, Ferland G, Gundberg C, Lands LC. Efficacy of high dose phylloquinone in correcting vitamin K deficiency in cystic fibrosis. J Cyst Fibros 2008;7:457-9.
11. van Hoorn JH, Hendriks JJ, Vermeer C, Forget PP. Vitamin K supplementation in cystic fibrosis. Arch Dis Child 2003;88:974-5.
12. Nicolaidou P, Stavrinadis I, Loukou I, et al. The effect of vitamin K supplementation on biochemical markers of bone formation in children and adolescents with cystic fibrosis. Eur J Pediatr 2006;165:540-5.
13. Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, et al. CDC growth charts: United States. Advance data from vital and health statistics; no. 314. Hyattsville, MD: National Center for Health Statistics, 2000:1-28.
14. Lohman TG, Roche AR, Martorell R. Anthropometric standardization reference manual. Champaign, IL: Human Kinetics, 1988.
15. Tanner JM. The development of the reproductive system. 2nd ed. Growth at adolescence. Oxford, United Kingdom: Blackwell Science, 1962:28-39.
16. Morris NM, Udry JR. Validation of a self-administered instrument to assess stage of adolescent development. J Youth Adolesc 1980;9:271-80.
17. Morris A, Kanner RE, Crapo R, Gardner RM. Clinical pulmonary function testing: a manual of uniform laboratory procedures. Salt Lake City, UT: Intermountain Thoracic Society, 1984.
18. Wang X, Dockery DW, Wypij D, Fay ME, Ferris BG Jr. Pulmonary function between 6 and 18 years of age. Pediatr Pulmonol 1993;15:75-88.
19. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 1999;159:179-87.
20. Gundberg CM, Nieman SD, Abrams S, Rosen H. Vitamin K status and bone health: an analysis of methods for determination of undercarboxylated osteocalcin. J Clin Endocrinol Metab 1998;83:3258-66. (Pubitemid 28500970)
21. Hollis BW, Kamerud JQ, Selvaag SR, Lorenz JD, Napoli JL. Determination of vitamin D status by radioimmunoassay with an 125I-labeled tracer. Clin Chem 1993;39:529-33.
22. Institute of Medicine. Dietary reference intakes for vitamin A, vitamin K, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickle, vanadium, and zinc. Washington, DC: National Academy Press, 2001.
23. Trabulsi J, Ittenbach RF, Schall JI, et al. Evaluation of formulas for calculating total energy requirements of preadolescent children with cystic fibrosis. Am J Clin Nutr 2007;85:144-51. (Pubitemid 46067628)
24. McKeown NM, Jacques PF, Gundberg CM, et al. Dietary and nondietary determinants of vitamin K biochemical measures in men and women. J Nutr 2002;132:1329-34.
25. Booth SL, Lichtenstein AH, O'Brien-Morse M, et al. Effects of a hydrogenated form of vitamin K on bone formation and resorption. Am J Clin Nutr 2001;74:783-90.
26. Booth SL, Martini L, Peterson JW, Saltzman E, Dallal GE, Wood RJ. Dietary phylloquinone depletion and repletion in older women. J Nutr 2003;133:2565-9.
27. Cystic Fibrosis Foundation Patient Registry. 2007 Annual data report. Bethesda, MD: Cystic Fibrosis Foundation, 2008.
28. Zemel B. The recognition and treatment of growth disorders - a 50-year retrospective. Ann Hum Biol 2009;36:496-510.
29. Zemel BS, Jawad AF, FitzSimmons S, Stallings VA. Longitudinal relationship among growth, nutritional status, and pulmonary function in children with cystic fibrosis: analysis of the Cystic Fibrosis Foundation National CF Patient Registry. J Pediatr 2000;137:374-80.
30. Stettler N, Kawchak DA, Boyle LL, et al. Prospective evaluation of growth, nutritional status, and body composition in children with cystic fibrosis. Am J Clin Nutr 2000;72:407-13.
31. Peterson ML, Jacobs DR Jr, Milla CE. Longitudinal changes in growth parameters are correlated with changes in pulmonary function in children with cystic fibrosis. Pediatrics 2003;112:588-92.
32. Corey M, McLaughlin FJ, Williams M, Levison H. A comparison of survival, growth, and pulmonary function in patients with cystic fibrosis in Boston and Toronto. J Clin Epidemiol 1988;41:583-91.
33. Stark LJ, Quittner AL, Powers SW, et al. Randomized clinical trial of behavioral intervention and nutrition education to improve caloric intake and weight in children with cystic fibrosis. Arch Pediatr Adolesc Med 2009;163:915-21.
34. Booth SL, Al Rajabi A. Determinants of vitamin K status in humans. Vitam Horm 2008;78:1-22.
35. van Summeren M, Braam L, Noirt F, Kuis W, Vermeer C. Pronounced elevation of undercarboxylated osteocalcin in healthy children. Pediatr Res 2007;61:366-70.
36. van Summeren MJ, Braam LA, Lilien MR, Schurgers LJ, Kuis W, Vermeer C. The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children. Br J Nutr 2009;102:1171-8.