Dexamethasone for postoperative nausea and vomiting: Time for a definitive phase IV trial

Anaesthesia and Intensive Care

Volumn 38, Issue 4, 2010, Pages 619-620

  Ho, K M ^a  

^a ROYAL PERTH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIEMETIC AGENT; CORTICOSTEROID; DEXAMETHASONE; HYDROCORTISONE;

ADRENAL SUPPRESSION; AIRWAY; BREAST SURGERY; CHOLECYSTECTOMY; COLON SURGERY; DRUG MEGADOSE; DRUG POTENCY; DRUG USE; EAR SURGERY; EDITORIAL; HEART ATRIUM FIBRILLATION; HEART SURGERY; HUMAN; HYDROCORTISONE RELEASE; HYPERGLYCEMIA; INFECTION RISK; INTESTINE RESECTION; ORTHOGNATHIC SURGERY; ORTHOPEDIC SURGERY; POSTOPERATIVE ANALGESIA; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; SIDE EFFECT; SINGLE DRUG DOSE; SURGICAL INFECTION; SWELLING; TONSILLECTOMY; CLINICAL TRIAL; METHODOLOGY; NOTE; SURGERY;

ANTIEMETICS; CLINICAL TRIALS AS TOPIC; DEXAMETHASONE; HUMANS; POSTOPERATIVE NAUSEA AND VOMITING; SURGICAL PROCEDURES, OPERATIVE;

EID: 77956641501     PISSN: 0310057X     EISSN: 14480271     Source Type: Journal    
DOI: 10.1177/0310057x1003800402     Document Type: Editorial

References (17)

1. Tsukuda M, Ishitoya J, Mikami Y, Matsuda H, Katori H, Horiuchi C et al. Antiemetic effects of granisetron and dexamethasone combination therapy during cisplatin-containing chemotherapy for head and neck cancer: dexamethasone dosage verification trial. Int J Clin Oncol 2009; 14:337-343.
2. Makhdoom NK, Farid MF. Prophylactic antiemetic effects of midazolam, dexamethasone, and its combination after middle ear surgery. Saudi Med J 2009; 30:504-508.
3. Mathew PJ, Madan R, Subramaniam R, Bhatia A, Mala CG, Soodan A et al. Efficacy of low-dose dexamethasone for preventing postoperative nausea and vomiting following strabismus repair in children. Anaesth Intensive Care 2004; 32:372-376. (Pubitemid 38877800)
4. Fujii Y, Nakayama M. Dexamethasone for the reduction of postoperative nausea and vomiting and analgesic requirements after middle ear surgery in adult Japanese patients. Methods Find Exp Clin Pharmacol 2009; 31:337-340.
5. Weber CR, Griffin JM. Evaluation of dexamethasone for reducing postoperative edema and inflammatory response after orthognathic surgery. J Oral Maxillofac Surg 1994; 52:35-39.
6. Ho KM, Tan JA. Benefits and risks of corticosteroid prophylaxis in adult cardiac surgery: a dose-response meta-analysis. Circulation 2009; 119:1853-1866.
7. Czarnetzki C, Elia N, Lysakowski C, Dumont L, Landis BN, Giger R et al. Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial. JAMA 2008; 300:2621-2630.
8. Neff SP, Stapelberg F, Warmington A. Excruciating perineal pain after intravenous dexamethasone. Anaesth Intensive Care 2002; 30:370-371. (Pubitemid 34619032)
9. Thackray NM, Bjorksten AR, Platt P. Phenytoin and dexamethasone induced resistance to vecuronium. Anaesth Intensive Care 1997; 25:184.
10. Eubanks TR, Greenberg JJ, Dobrin PB, Harford FJ, Gamelli RL. The effects of different corticosteroids on the healing colon anastomosis and cecum in a rat model. Am Surg 1997; 63:266-269.
11. Polat A, Nayci A, Polat G, Aksöyek S. Dexamethasone downregulates endothelial expression of intercellular adhesion molecule and impairs the healing of bowel anastomoses. Eur J Surg 2002; 168:500-506. (Pubitemid 36020895)
12. Sano T, Morita S, Masuda M, Yasui H. Minor infection encouraged by steroid administration during cardiac surgery. Asian Cardiovasc Thorac Ann 2006; 14:505-510. (Pubitemid 44883683)
13. Percival VG, Riddle J, Corcoran TB. Single-dose dexamethasone for postoperative nausea and vomiting - a matched case-control study of operative infection risk. Anaesth Intensive Care 2010; 38:661-666.
14. Corocran TB, Truyens E, Ng A, Moseley N, Doyle A, Margetts L. Antiemetic dexamethasone and postoperative infection risk; a retrospective cohort study. Anaesth Intensive Care 2010; 38:654-660.
15. Cowie B, Allen K, Said S, Inder W. Antiemetic doses of dexamethasone suppress cortisol response in laparoscopic cholecystectomy. Anaesth Intensive Care 2010; 38:667-670.
16. Jurek AM, Greenland S, Maldonado G. How far from non-differential does exposure or disease misclassification have to be to bias measures of association away from the null? Int J Epidemiol 2008; 37:382-385.
17. Fewell Z, Davey Smith G, Sterne JA. The impact of residual and unmeasured confounding in epidemiologic studies: a simulation study. Am J Epidemiol 2007; 166:646-655. (Pubitemid 47347902)