메뉴 건너뛰기




Volumn 127, Issue 9, 2010, Pages 2230-2237

Pak1 and Pak2 are activated in recurrent respiratory papillomas, contributing to one pathway of Rac1-mediated COX-2 expression

Author keywords

COX 2; HPV; Pak1; Pak2; Rac1; respiratory papillomas

Indexed keywords

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; P21 ACTIVATED KINASE 1; P21 ACTIVATED KINASE 2; RAC1 PROTEIN; SMALL INTERFERING RNA; P21 ACTIVATED KINASE; PAK1 PROTEIN, HUMAN; PAK2 PROTEIN, HUMAN;

EID: 77956640958     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25226     Document Type: Article
Times cited : (23)

References (34)
  • 1
    • 0004881963 scopus 로고
    • Viral etiology of juvenile-and adult-onset squamous papilloma of the larynx
    • Mounts P, Shah KV, Kashima H,. Viral etiology of juvenile-and adult-onset squamous papilloma of the larynx. Proc Natl Acad Sci USA 1982; 79: 5425 -9.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 5425-9
    • Mounts, P.1    Shah, K.V.2    Kashima, H.3
  • 2
    • 0019948750 scopus 로고
    • Molecular cloning and characterization of human papillomavirus DNA derived from a laryngeal papilloma
    • Gissman L, Diehl B, Schults-Coulon J, zur Hausen H,. Molecular cloning and characterization of human papillomavirus DNA derived from a laryngeal papilloma. J Virol 1982; 44: 393 -9.
    • (1982) J Virol , vol.44 , pp. 393-9
    • Gissman, L.1    Diehl, B.2    Schults-Coulon, J.3    Zur Hausen, H.4
  • 3
    • 35248819685 scopus 로고    scopus 로고
    • The spectrum and clinical sequelae of human papillomavirus infection
    • Monk BJ, Tewari KS,. The spectrum and clinical sequelae of human papillomavirus infection. Gynecol Oncol 2007; 107: S6 -S13.
    • (2007) Gynecol Oncol , vol.107
    • Monk, B.J.1    Tewari, K.S.2
  • 4
    • 0027474459 scopus 로고
    • Laryngeal papilloma cells have high levels of epidermal growth factor receptor and respond to epidermal growth factor by a decrease in epithelial differentiation
    • Vambutas A, Di Lorenzo TP, Steinberg BM,. Laryngeal papilloma cells have high levels of epidermal growth factor receptor and respond to epidermal growth factor by a decrease in epithelial differentiation. Cancer Res 1993; 53: 910 -14.
    • (1993) Cancer Res , vol.53 , pp. 910-14
    • Vambutas, A.1    Di Lorenzo, T.P.2    Steinberg, B.M.3
  • 5
    • 0033558283 scopus 로고    scopus 로고
    • Elevation of the epidermal growth factor receptor and dependent signaling in human papillomavirus-infected laryngeal papillomas
    • Johnston D, Hall H, Dilorenzo TP, Steinberg BM,. Elevation of the epidermal growth factor receptor and dependent signaling in human papillomavirus-infected laryngeal papillomas. Cancer Res 1999; 59: 968 -74.
    • (1999) Cancer Res , vol.59 , pp. 968-74
    • Johnston, D.1    Hall, H.2    Dilorenzo, T.P.3    Steinberg, B.M.4
  • 6
    • 0034161898 scopus 로고    scopus 로고
    • Overexpression of PTEN/MMAC1 and decreased activation of Akt in human papillomavirus-infected laryngeal papillomas
    • Zhang P, Steinberg BM,. Overexpression of PTEN/MMAC1 and decreased activation of Akt in human papillomavirus-infected laryngeal papillomas. Cancer Res 2000; 60: 1457 -62.
    • (2000) Cancer Res , vol.60 , pp. 1457-62
    • Zhang, P.1    Steinberg, B.M.2
  • 7
    • 0036298183 scopus 로고    scopus 로고
    • PTEN is a negative regulator of STAT3 activation in human papillomavirus-infected cells
    • Sun S, Steinberg BM,. PTEN is a negative regulator of STAT3 activation in human papillomavirus-infected cells. J Gen Virol 2002; 83: 1651 -8.
    • (2002) J Gen Virol , vol.83 , pp. 1651-8
    • Sun, S.1    Steinberg, B.M.2
  • 8
    • 0038648321 scopus 로고    scopus 로고
    • Requirement of STAT3 activation for differentiation of mucosal stratified squamous epithelium
    • Wu R, Sun S, Steinberg BM,. Requirement of STAT3 activation for differentiation of mucosal stratified squamous epithelium. Mol Med 2003; 9: 77 -84.
    • (2003) Mol Med , vol.9 , pp. 77-84
    • Wu, R.1    Sun, S.2    Steinberg, B.M.3
  • 9
    • 34250638197 scopus 로고    scopus 로고
    • Up-regulation of Rac1 by epidermal growth factor mediates COX-2 expression in recurrent respiratory papillomas
    • Wu R, Coniglio SJ, Chan A, Symons MH, Steinberg BM,. Up-regulation of Rac1 by epidermal growth factor mediates COX-2 expression in recurrent respiratory papillomas. Mol Med 2007; 13: 143 -50.
    • (2007) Mol Med , vol.13 , pp. 143-50
    • Wu, R.1    Coniglio, S.J.2    Chan, A.3    Symons, M.H.4    Steinberg, B.M.5
  • 10
    • 0036147584 scopus 로고    scopus 로고
    • Increased p50/p50 NF-kappaB activation in human papillomavirus type 6-or type 11-induced laryngeal papilloma tissue
    • Vancurova I, Wu R, Miskolci V, Sun S,. Increased p50/p50 NF-kappaB activation in human papillomavirus type 6-or type 11-induced laryngeal papilloma tissue. J Virol 2002; 76: 1533 -6.
    • (2002) J Virol , vol.76 , pp. 1533-6
    • Vancurova, I.1    Wu, R.2    Miskolci, V.3    Sun, S.4
  • 11
    • 24344477064 scopus 로고    scopus 로고
    • Epidermal growth factor-induced cyclooxygenase-2 expression is mediated through phosphatidylinositol-3 kinase, not mitogen-activated protein/extracellular signal-regulated kinase kinase, in recurrent respiratory papillomas
    • Wu R, Abramson AL, Shikowitz MJ, Dannenberg AJ, Steinberg BM,. Epidermal growth factor-induced cyclooxygenase-2 expression is mediated through phosphatidylinositol-3 kinase, not mitogen-activated protein/extracellular signal-regulated kinase kinase, in recurrent respiratory papillomas. Clin Cancer Res 2005; 11: 6155 -61.
    • (2005) Clin Cancer Res , vol.11 , pp. 6155-61
    • Wu, R.1    Abramson, A.L.2    Shikowitz, M.J.3    Dannenberg, A.J.4    Steinberg, B.M.5
  • 12
    • 0036669611 scopus 로고    scopus 로고
    • Cyclooxygenase isozymes and their gene structures and expression
    • Tanabe T, Tohnai N,. Cyclooxygenase isozymes and their gene structures and expression. Prostaglandins Other Lipid Mediat 2002; 68/69: 95 -114.
    • (2002) Prostaglandins Other Lipid Mediat , vol.6869 , pp. 95-114
    • Tanabe, T.1    Tohnai, N.2
  • 13
    • 0346365370 scopus 로고    scopus 로고
    • Activation of nuclear factor-°B p50 homodimer/Bcl3 complexes in nasopharyngeal carcinoma
    • Thornburg NJ, Pathmanathan R, Raab-Traub N,. Activation of nuclear factor-°B p50 homodimer/Bcl3 complexes in nasopharyngeal carcinoma. Cancer Res 2003; 63: 8293 -301.
    • (2003) Cancer Res , vol.63 , pp. 8293-301
    • Thornburg, N.J.1    Pathmanathan, R.2    Raab-Traub, N.3
  • 14
    • 33750160826 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled phase II trial of the cyclooxygenase-2 inhibitor Celecoxib in the treatment of cervical dysplasia
    • Farley JH, Truong V, Goo E, Uyehara C, Belnap C, Larsen WI,. A randomized double-blind placebo-controlled phase II trial of the cyclooxygenase-2 inhibitor Celecoxib in the treatment of cervical dysplasia. Gynecol Oncol 2006; 103: 425 -30.
    • (2006) Gynecol Oncol , vol.103 , pp. 425-30
    • Farley, J.H.1    Truong, V.2    Goo, E.3    Uyehara, C.4    Belnap, C.5    Larsen, W.I.6
  • 15
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser E, Leung T, Salihuddin H, Zhao ZS, Lim L,. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 1994; 367: 40 -6.
    • (1994) Nature , vol.367 , pp. 40-6
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.S.4    Lim, L.5
  • 16
    • 0036223236 scopus 로고    scopus 로고
    • P21-activated kinases: Three more join the Pak
    • Jaffer ZM, Chernoff J,. p21-activated kinases: three more join the Pak. Int J Biochem Biol 2002; 34: 713 -17.
    • (2002) Int J Biochem Biol , vol.34 , pp. 713-17
    • Jaffer, Z.M.1    Chernoff, J.2
  • 17
    • 0038554077 scopus 로고    scopus 로고
    • Biology of the p21-activated kinases
    • Bokoch GM,. Biology of the p21-activated kinases. Annu Rev Biochem 2003; 72: 743 -81.
    • (2003) Annu Rev Biochem , vol.72 , pp. 743-81
    • Bokoch, G.M.1
  • 18
    • 0028842508 scopus 로고
    • Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets
    • Teo M, Manser E, Lim L,. Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets. J Biol Chem 1995; 270: 26690 -7.
    • (1995) J Biol Chem , vol.270 , pp. 26690-7
    • Teo, M.1    Manser, E.2    Lim, L.3
  • 19
    • 0028862297 scopus 로고
    • Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family
    • Manser E, Chong C, Zhao ZS, Leung T, Michael G, Hall C, Lim L,. Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family. J Biol Chem 1995; 270: 25070 -8.
    • (1995) J Biol Chem , vol.270 , pp. 25070-8
    • Manser, E.1    Chong, C.2    Zhao, Z.S.3    Leung, T.4    Michael, G.5    Hall, C.6    Lim, L.7
  • 22
    • 44949176114 scopus 로고    scopus 로고
    • Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms
    • Coniglio SJ, Zavarella S, Symons MH,. Pak1 and Pak2 mediate tumor cell invasion through distinct signaling mechanisms. Mol Cell Biol 2008; 28: 4162 -72.
    • (2008) Mol Cell Biol , vol.28 , pp. 4162-72
    • Coniglio, S.J.1    Zavarella, S.2    Symons, M.H.3
  • 26
    • 0024422238 scopus 로고
    • Differentiation-linked human papillomavirus types 6 and 11 transcription in genital condylomata revealed by in situ hybridization with message-specific RNA probes
    • Stoler MH, Wolinsky SM, Whitbeck A, Broker TR, Chow LT,. Differentiation-linked human papillomavirus types 6 and 11 transcription in genital condylomata revealed by in situ hybridization with message-specific RNA probes. Virology 1989; 172: 331 -40.
    • (1989) Virology , vol.172 , pp. 331-40
    • Stoler, M.H.1    Wolinsky, S.M.2    Whitbeck, A.3    Broker, T.R.4    Chow, L.T.5
  • 27
    • 14844293207 scopus 로고    scopus 로고
    • PAK and other Rho-associated kinases effectors with surprisingly diverse mechanisms of regulation
    • Zhao ZS, Manser E,. PAK and other Rho-associated kinases effectors with surprisingly diverse mechanisms of regulation. Biochem J 2005; 386 (Part 2): 201 -14.
    • (2005) Biochem J , vol.386 , Issue.PART 2 , pp. 201-14
    • Zhao, Z.S.1    Manser, E.2
  • 28
    • 41949100602 scopus 로고    scopus 로고
    • An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase
    • Deacon SW, Beeser A, Fukui JA, Rennefahrt UE, Myers C, Chernoff J, Peterson JR,. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem Biol 2008; 15: 322 -31.
    • (2008) Chem Biol , vol.15 , pp. 322-31
    • Deacon, S.W.1    Beeser, A.2    Fukui, J.A.3    Rennefahrt, U.E.4    Myers, C.5    Chernoff, J.6    Peterson, J.R.7
  • 29
    • 0034733041 scopus 로고    scopus 로고
    • Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1
    • Frost JA, Swantek JL, Stippec S, Yin MJ, Gaynor R, Cobb MH,. Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1. J Biol Chem 2000; 275: 19693 -9.
    • (2000) J Biol Chem , vol.275 , pp. 19693-9
    • Frost, J.A.1    Swantek, J.L.2    Stippec, S.3    Yin, M.J.4    Gaynor, R.5    Cobb, M.H.6
  • 30
    • 0346690266 scopus 로고    scopus 로고
    • Activation of p21-activated kinase 1-nuclear factor kappaB signaling by Kaposi's sarcoma-associated herpes virus G protein-coupled receptor during cellular transformation
    • Dadke D, Fryer BH, Golemis EA, Field J,. Activation of p21-activated kinase 1-nuclear factor kappaB signaling by Kaposi's sarcoma-associated herpes virus G protein-coupled receptor during cellular transformation. Cancer Res 2003; 63: 8837 -47.
    • (2003) Cancer Res , vol.63 , pp. 8837-47
    • Dadke, D.1    Fryer, B.H.2    Golemis, E.A.3    Field, J.4
  • 31
    • 0031034814 scopus 로고    scopus 로고
    • Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells
    • Schmedtje JF, Jr, Ji YS, Liu WL, DuBois RN, Runge MS,. Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells. J Biol Chem 1997; 272: 601 -8.
    • (1997) J Biol Chem , vol.272 , pp. 601-8
    • Schmedtje Jr., J.F.1    Ji, Y.S.2    Liu, W.L.3    Dubois, R.N.4    Runge, M.S.5
  • 32
    • 0032489318 scopus 로고    scopus 로고
    • Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells
    • Inoue H, Tanabe T,. Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells. Biochem Biophys Res Commun 1998; 244: 143 -8.
    • (1998) Biochem Biophys Res Commun , vol.244 , pp. 143-8
    • Inoue, H.1    Tanabe, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.