-
1
-
-
0035048096
-
Cytokine therapy for metastatic renal cell carcinoma
-
R.M. Bukowski Cytokine therapy for metastatic renal cell carcinoma Semin Urol Oncol 19 2001 148
-
(2001)
Semin Urol Oncol
, vol.19
, pp. 148
-
-
Bukowski, R.M.1
-
2
-
-
67650327598
-
Metastatic renal cell carcinoma: Many treatment options, one patient
-
B.I. Rini Metastatic renal cell carcinoma: many treatment options, one patient J Clin Oncol 27 2009 3225
-
(2009)
J Clin Oncol
, vol.27
, pp. 3225
-
-
Rini, B.I.1
-
3
-
-
0035496921
-
Apo2L/TRAIL and Bcl-2-related proteins regulate type i interferon-induced apoptosis in multiple myeloma
-
Q. Chen, B. Gong, and A.S. Mahmoud-Ahmed Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma Blood 98 2001 2183
-
(2001)
Blood
, vol.98
, pp. 2183
-
-
Chen, Q.1
Gong, B.2
Mahmoud-Ahmed, A.S.3
-
4
-
-
0034895641
-
Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: Correlation with TRAIL/Apo2L induction in melanoma cell lines
-
M. Chawla-Sarkar, D.W. Leaman, and E.C. Borden Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines Clin Cancer Res 7 2001 1821
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1821
-
-
Chawla-Sarkar, M.1
Leaman, D.W.2
Borden, E.C.3
-
5
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
R.M. Pitti, S.A. Marsters, and S. Ruppert Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family J Biol Chem 271 1996 12687
-
(1996)
J Biol Chem
, vol.271
, pp. 12687
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
-
6
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
S.R. Wiley, K. Schooley, and P.J. Smolak Identification and characterization of a new member of the TNF family that induces apoptosis Immunity 3 1995 673
-
(1995)
Immunity
, vol.3
, pp. 673
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
-
7
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
A. Ashkenazi, R.C. Pai, and S. Fong Safety and antitumor activity of recombinant soluble Apo2 ligand J Clin Invest 104 1999 155
-
(1999)
J Clin Invest
, vol.104
, pp. 155
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
-
8
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
H. Walczak, R.E. Miller, and K. Ariail Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo Nat Med 5 1999 157
-
(1999)
Nat Med
, vol.5
, pp. 157
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
-
9
-
-
70349318434
-
Mapatumumab, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: Results of a phase i and pharmacokinetic study
-
S. Leong, R.B. Cohen, and D.L. Gustafson Mapatumumab, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: results of a phase I and pharmacokinetic study J Clin Oncol 27 2009 4413
-
(2009)
J Clin Oncol
, vol.27
, pp. 4413
-
-
Leong, S.1
Cohen, R.B.2
Gustafson, D.L.3
-
10
-
-
35948952826
-
Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers
-
R. Plummer, G. Attard, and S. Pacey Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers Clin Cancer Res 13 2007 6187
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6187
-
-
Plummer, R.1
Attard, G.2
Pacey, S.3
-
11
-
-
0032750511
-
Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
-
J. Mongkolsapaya, J.M. Grimes, and N. Chen Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation Nat Struct Biol 6 1999 1048
-
(1999)
Nat Struct Biol
, vol.6
, pp. 1048
-
-
Mongkolsapaya, J.1
Grimes, J.M.2
Chen, N.3
-
12
-
-
0346792725
-
TRAIL and apoptosis induction by TNF-family death receptors
-
S. Wang, and W.S. El-Deiry TRAIL and apoptosis induction by TNF-family death receptors Oncogene 22 2003 8628
-
(2003)
Oncogene
, vol.22
, pp. 8628
-
-
Wang, S.1
El-Deiry, W.S.2
-
13
-
-
0037273848
-
Apo2L/TRAIL and its death and decoy receptors
-
H.N. LeBlanc, and A. Ashkenazi Apo2L/TRAIL and its death and decoy receptors Cell Death Differ 10 2003 66
-
(2003)
Cell Death Differ
, vol.10
, pp. 66
-
-
Leblanc, H.N.1
Ashkenazi, A.2
-
14
-
-
0037444380
-
Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel
-
J. Asakuma, M. Sumitomo, and T. Asano Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel Cancer Res 63 2003 1365
-
(2003)
Cancer Res
, vol.63
, pp. 1365
-
-
Asakuma, J.1
Sumitomo, M.2
Asano, T.3
-
15
-
-
0042845974
-
Progressive resistance of BTK-143 osteosarcoma cells to Apo2L/TRAIL-induced apoptosis is mediated by acquisition of DcR2/TRAIL-R4 expression: Resensitisation with chemotherapy
-
S. Bouralexis, D.M. Findlay, and G.J. Atkins Progressive resistance of BTK-143 osteosarcoma cells to Apo2L/TRAIL-induced apoptosis is mediated by acquisition of DcR2/TRAIL-R4 expression: resensitisation with chemotherapy Br J Cancer 89 2003 206
-
(2003)
Br J Cancer
, vol.89
, pp. 206
-
-
Bouralexis, S.1
Findlay, D.M.2
Atkins, G.J.3
-
16
-
-
0034736062
-
Genomic organization and transcriptional regulation of human Apo2/TRAIL gene
-
B. Gong, and A. Almasan Genomic organization and transcriptional regulation of human Apo2/TRAIL gene Biochem Biophys Res Commun 278 2000 747
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 747
-
-
Gong, B.1
Almasan, A.2
-
17
-
-
0037100434
-
IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis
-
M. Chawla-Sarkar, D.W. Leaman, and B.S. Jacobs IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis J Immunol 169 2002 847
-
(2002)
J Immunol
, vol.169
, pp. 847
-
-
Chawla-Sarkar, M.1
Leaman, D.W.2
Jacobs, B.S.3
-
18
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
T.C. Chou, and P. Talalay Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors Adv Enzyme Regul 22 1984 27
-
(1984)
Adv Enzyme Regul
, vol.22
, pp. 27
-
-
Chou, T.C.1
Talalay, P.2
-
19
-
-
34247145009
-
Lexatumumab (TRAIL-receptor 2 mAb) induces expression of DR5 and promotes apoptosis in primary and metastatic renal cell carcinoma in a mouse orthotopic model
-
L. Zhang, X. Zhang, and G.W. Barrisford Lexatumumab (TRAIL-receptor 2 mAb) induces expression of DR5 and promotes apoptosis in primary and metastatic renal cell carcinoma in a mouse orthotopic model Cancer Lett 251 2007 146
-
(2007)
Cancer Lett
, vol.251
, pp. 146
-
-
Zhang, L.1
Zhang, X.2
Barrisford, G.W.3
-
20
-
-
0036606414
-
Induction and regulation of tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand-mediated apoptosis in renal cell carcinoma
-
T.S. Griffith, J.M. Fialkov, and D.L. Scott Induction and regulation of tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand-mediated apoptosis in renal cell carcinoma Cancer Res 62 2002 3093
-
(2002)
Cancer Res
, vol.62
, pp. 3093
-
-
Griffith, T.S.1
Fialkov, J.M.2
Scott, D.L.3
-
21
-
-
65349112511
-
TRAIL gene therapy: From preclinical development to clinical application
-
T.S. Griffith, B. Stokes, and T.A. Kucaba TRAIL gene therapy: from preclinical development to clinical application Curr Gene Ther 9 2009 9
-
(2009)
Curr Gene Ther
, vol.9
, pp. 9
-
-
Griffith, T.S.1
Stokes, B.2
Kucaba, T.A.3
-
22
-
-
52649109068
-
The TRAIL apoptotic pathway in cancer onset, progression and therapy
-
R.W. Johnstone, A.J. Frew, and M.J. Smyth The TRAIL apoptotic pathway in cancer onset, progression and therapy Nat Rev Cancer 8 2008 782
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 782
-
-
Johnstone, R.W.1
Frew, A.J.2
Smyth, M.J.3
-
23
-
-
0942298610
-
TRAIL regulates normal erythroid maturation through an ERK-dependent pathway
-
P. Secchiero, E. Melloni, and M. Heikinheimo TRAIL regulates normal erythroid maturation through an ERK-dependent pathway Blood 103 2004 517
-
(2004)
Blood
, vol.103
, pp. 517
-
-
Secchiero, P.1
Melloni, E.2
Heikinheimo, M.3
-
24
-
-
39849092395
-
Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily
-
J.J. Song, and Y.J. Lee Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily Cell Signal 20 2008 892
-
(2008)
Cell Signal
, vol.20
, pp. 892
-
-
Song, J.J.1
Lee, Y.J.2
-
25
-
-
0035844129
-
MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors
-
S.E. Tran, T.H. Holmstrom, and M. Ahonen MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors J Biol Chem 276 2001 16484
-
(2001)
J Biol Chem
, vol.276
, pp. 16484
-
-
Tran, S.E.1
Holmstrom, T.H.2
Ahonen, M.3
-
26
-
-
33750584261
-
Anti-apoptotic hPEBP4 silencing promotes TRAIL-induced apoptosis of human ovarian cancer cells by activating ERK and JNK pathways
-
P. Li, X. Wang, and N. Li Anti-apoptotic hPEBP4 silencing promotes TRAIL-induced apoptosis of human ovarian cancer cells by activating ERK and JNK pathways Int J Mol Med 18 2006 505
-
(2006)
Int J Mol Med
, vol.18
, pp. 505
-
-
Li, P.1
Wang, X.2
Li, N.3
-
27
-
-
42649100263
-
Quercetin augments TRAIL-induced apoptotic death: Involvement of the ERK signal transduction pathway
-
Y.H. Kim, D.H. Lee, and J.H. Jeong Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway Biochem Pharmacol 75 2008 1946
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1946
-
-
Kim, Y.H.1
Lee, D.H.2
Jeong, J.H.3
-
28
-
-
0036644873
-
Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases
-
D. Xiao, and S.V. Singh Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases Cancer Res 62 2002 3615
-
(2002)
Cancer Res
, vol.62
, pp. 3615
-
-
Xiao, D.1
Singh, S.V.2
-
29
-
-
17644417124
-
Role of ERK in hydrogen peroxide-induced cell death of human glioma cells
-
W.C. Lee, C.H. Choi, and S.H. Cha Role of ERK in hydrogen peroxide-induced cell death of human glioma cells Neurochem Res 30 2005 263
-
(2005)
Neurochem Res
, vol.30
, pp. 263
-
-
Lee, W.C.1
Choi, C.H.2
Cha, S.H.3
-
30
-
-
70349989502
-
Benzyl isothiocyanate mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells
-
R.P. Sahu, R. Zhang, and S. Batra Benzyl isothiocyanate mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells Carcinogenesis 30 2009 1744
-
(2009)
Carcinogenesis
, vol.30
, pp. 1744
-
-
Sahu, R.P.1
Zhang, R.2
Batra, S.3
|