Genotype f prevails in Venezuelan urban patients with chronic hepatitis B

Annals of Hepatology

Volumn 9, Issue 2, 2010, Pages 172-176

  Machado, Irma V ^a   Fortes, María del Pilar ^a   Vargas Lovelle, Berta ^a   Trómpiz, Aleidy C ^a   López, Danerys A ^a   León, Roberto V ^b   Senior, Merita ^c   Dasher, Lucy ^d   López, Carmen E ^e   Pestana, Elena ^f   Bacalao, Román ^d   Garassini, Miguel E ^d  

^a Laboratorio Clínico Especializado Intediag HV   (Venezuela)

^b Hospital General del Oeste   (Venezuela)

^c Hospital de Clinicas Caracas   (Venezuela)

^d Centro Medico Docente La Trinidad   (Venezuela)

^e Hospital de Ninos J M de los Rios   (Venezuela)

^f Policlinica Metropolitana   (Venezuela)

Author keywords

Anti eHB antibodies; Chronic hepatitis B; E entigen; Genotype F; Urban HBV carrier

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B ANTIGEN; VIRUS DNA; BIOLOGICAL MARKER; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN;

ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTIGEN DETECTION; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE CARRIER; DISEASE COURSE; DISEASE TRANSMISSION; DNA DETERMINATION; FEMALE; GENETIC CORRELATION; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MIGRATION; SEROEPIDEMIOLOGY; URBAN POPULATION; VENEZUELA; VIRUS LOAD; VIRUS STRAIN; AGE DISTRIBUTION; BLOOD; GENETICS; IMMUNOLOGY; MIDDLE AGED; PRESCHOOL CHILD; PREVALENCE; PROGNOSIS; STATISTICS;

ADOLESCENT; ADULT; AGE DISTRIBUTION; BIOLOGICAL MARKERS; CHILD; CHILD, PRESCHOOL; DNA, VIRAL; FEMALE; GENOTYPE; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; MALE; MIDDLE AGED; PREVALENCE; PROGNOSIS; URBAN POPULATION; VENEZUELA; VIRAL LOAD;

EID: 77956622006     PISSN: 16652681     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1665-2681(19)31657-6     Document Type: Article

References (30)

1. Norder H, Courouce AM, Magnius LO. Completed genomes, phylogenetic relatedness, and structural proteins of six strains of the hepatitis B virus, four of which represent two new genotypes. Virology 1994; 198: 489-503.
2. Wai CH-T, Fontana RJ. Clinical Significance of Hepatitis B Virus Genotypes, Variants, and Mutants. Clin Liv Dis 2004; 8: 321-352.
3. Gish RG, Locarnini S. Genotyping and Genomic Sequencing in Clinical Practice. Clin Liv Dis 2007; 11: 761-795.
4. Liaw YF, Sollano JD. Factors influencing liver disease progression in chronic hepatitis B. Liver Int 2006; 26(Suppl. 2): 23-29.
5. Torres JR. Hepatitis B and hepatitis Delta virus infection in South America. Gut 1996: 38(Suppl. 2): S48-S55.
6. Machado IV, Carvajal J, Mondolfi A, Marcano N, Yarzabal L, Bianco NE. Seroepidemiological differences of HBV infection between urban areas and Amerindian population in Venezuela. In: Viral Hepatitis and Liver Disease. Zucker-man AJ (ed.). New York: Alan R. Liss; 1988, p. 174-176.
7. Devesa M, Pujol FH. Hepatitis B virus genetic diversity in Latin America. Virus Res 2007; 127: 177-184.
8. Chevaliez S, Pawlotsky J-M. Virological techniques for the diagnosis and monitoring of hepatitis B and C. Ann Hepatol 2009; 8: 7-12.
9. Stelz E, Muller Z, Marth E, Kessler HH. Rapid Quantification of hepatitis B virus DNA by automated sample preparation and real-time PCR. J Clin Microbiol 2004; 42: 2445-2449.
10. Fortes MP, Trompiz A, Canonico Y, Vargas-Lovelle B, Machado IV. La frecuencia del genotipo 1 del virus de la hepatitis C no ha variado en Venezuela. Rev Col Gastroenterol 2009; 24: 256-258.
11. Naito H, Hayashi S, Abe K. Rapid and specific genotyping system for hepatitis B virus corresponding to six major genotypes by PCR using type-specific primers. J Clin Microbiol 2001; 39: 362-364.
12. Blitz L, Pujol FH, Swenson PD, Porto L, Atencio R, Araujo M, Costa L, et al. Antigenic Diversity of Hepatitis B Virus Strains of Genotype F in Amerindians and Other Population Groups from Venezuela. J Clin Microbiol 1998; 36: 648-651.
13. Devesa M, Loureiro CL, Rivas Y, Monsalve F, Cardona N, Duarte MC, Poblete F, et al. Subgenotype diversity of hepatitis B virus American genotype F in Amerindians from Venezuela and the general population of Colombia. J Med Virol 2008; 80: 20-26.
14. Mello FCA, Souto FJD, Tabuco LC, Villela-Nogueira CA, Coelho HSM, Franz HCF, Saraiva JCP, et al. Hepatitis B virus genotypes circulating in Brazil: molecular characterization of genotypes F isolates. BMC Microbiology 2007; 7: 103. Available on-line: htpp://www.biocentral.com/1471-2180/7/103
15. Makhatadze N, Franco MT, Layrisse Z. HLA class I and class II allele and haplotype distribution in the Venezuelan population. Hum Immunol 1997; 55: 53-58.
16. Sanchez-Tapias JM, Costa J, Mas A, Bruguera M, Rodes J. Influence of hepatitis B virus genotype on the long-term outcome of chronic hepatitis B in Western patients. Gastroenterology 2002; 123: 1848-1856.
17. Zabaleta ME, Toro Fl, Ruiz ME, Colmenares CJ, Bianco NE, Machado IV. Assessment of former and newly developed HBV assays in a third world setting. J Med Virol 1992; 38: 240-245.
18. Machado IV, Deibis L, Risquez E, Tassinari P, Zabaleta ME, Toro Fl, Baroja ML, et al. Abordaje Inmunoclinico, Molecular e Inmunopatologico de la hepatitis cronica viral. Consideraciones Terapeuticas. GEN 1994; 48: 124-132.
19. Baroja ML, Sirit FL, Toro Fl, Rivera H, Garzaro J, Bianco NE, Machado IV. T-cell hyperreactivity to IL-6 in chronic non-viremic HBV carriers despite normal IL-6 receptor or gp130 expression. Viral Immunol 1996; 9: 187-194.
20. Leon RV, Machado IV. A further definition of the major consequences of chronic hepatitis B in Venezuela. J Clin Virol 2006; 36 (Suppl. 2): S208.
21. EASL Clinical Practice Guidelines: Management of chronic hepatitis B. J Hepatol 2009; 50: 227-242.
22. Strauss E. Barriers to care of chronic hepatitis patients in Latin America. Arch Med Res 2007; 38: 711-715.
23. Livingston SE, Simonetti JP, McMahon BJ, Bulkow LR, Hurlburt KJ, Homan CE, Snowball MM, et al. Hepatitis B virus genotypes in Alaska Native people with hepatocellular carcinoma: preponderance of genotype F. J Infect Dis 2007; 195: 5-11.
24. Diaz MS, Bastrado GNA, Roizental M, Dagher L. Analisis de caracteristicas etiologicas y demograficas asociadas a carcinoma hepatocelular en pacientes tratados en un Ser-vicio de Radiologia Intervencionista de Referenda. Ann Hepatol 2008; 302: 8
25. Torres JR, Machado IV. Special aspects of Hepatitis B Virus and Delta Virus Infection in Latin America. Inf Dis Clin North Am 1994; 8: 13-27.
26. Machado IV, Deibis L, Zabaleta M, Toro Fl, Marino V, Ramirez JL, et al. Assessment of Delta Virus Infection in Venezuelan high-risk population for hepatitis B virus. Clin Biol Res 1991; 364: 105-113.
27. EL-Serag HB, Lenhard-Rudolph K. Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis. Gastroenterology 2007; 132: 2557-76.
28. Lopez CE. Hepatitis B y C en pacientes pediatrics oncologics. Rev Chil. Nut 2009; 36:85.
29. Machado IV, Marcano NB, Rosales A, Rincon R, Carvajal J, Rivero MT, Muhoz JF, et al. Riesgo de exposicion ocupa-cional al virus de la hepatitis B en personal de salud vene-zolano. Estudio multicentric GEN 1990; 44: 1-8.
30. Fernandez Barboza R, Rivero D, Echeverria B, Machado IV. Costo-beneficio de la vacunacion contra la hepatitis B en trabajadores de hospitales de Venezuela. Bol Of Sanit Panam 1991; 111: 16-23.