Mitochondrial viability in mouse and human postmortem brain

FASEB Journal

Volumn 24, Issue 9, 2010, Pages 3590-3599

  Barksdale, Keri A ^a   Perez Costas, Emma ^a   Gandy, Johanna C ^a   Melendez Ferro, Miguel ^a   Roberts, Rosalinda C ^a   Bijur, Gautam N ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

ATP; Cortex; Electron microscopy; Membrane potential; Rhodamine

Indexed keywords

ADENOSINE TRIPHOSPHATE;

ADULT; AGED; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; DEATH; FEMALE; HUMAN; HUMAN TISSUE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY CHAIN;

ADENOSINE TRIPHOSPHATE; ANIMALS; HUMANS; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; POSTMORTEM CHANGES; TIME FACTORS;

EID: 77956620356     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-152108     Document Type: Article

References (29)

1. Nukala, V. N., Singh, I. N., Davis, L. M., and Sullivan, P. G. (2005) Cryopreservation of brain mitochondria: A novel methodology for functional studies. J. Neurosci. Methods 152, 48-54
2. Wang, X., Su, B., Zheng, L., Perry, G., Smith, M. A., and Zhu, X. (2009) The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J. Neurochem. 109, 153-159
3. Vila, M., Ramonet, D., and Perier, C. (2008) Mitochondrial alterations in Parkinson's disease: new clues. J. Neurochem. 107, 317-328
4. 2+ overload than non-synaptic mitochondria. J. Biol. Chem. 281, 11658-11668
5. 2+ dyshomeostasis drive neuronal pathology in diabetes. Cell Calcium 44, 112-122
6. Rollins, B., Martin, M. V., Sequeira, P. A., Moon, E. A., Morgan, L. Z., Watson, S. J., Schatzberg, A., Akil, H., Myers, R. M., Jones, E. G., Wallace, D. C., Bunney, W. E., and Vawter, M. P. (2009) Mitochondrial variants in schizophrenia, bipolar disorder, and major depressive disorder. PLoS One 4, 4913
7. Gerards, M., Sluiter, W., van den Bosch, B. J., de Wit, E., Calis, C. M., Frentzen, M., Akbari, H., Schoonderwoerd, K., Scholte, H. R., Jongbloed, R. J., Hendrickx, A. T., de Coo, I. F., and Smeets, H. J. (2009) Defective complex I assembly due to C20orf7 mutations as a new cause of Leigh syndrome. [E-pub ahead of print] J. Med. Genet. PMID 19542079
8. Devi, L., Raghavendran, V., Prabhu, B. M., Avadhani, N. G., and Anandatheerthavarada, H. K. (2008) Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J. Biol. Chem. 283, 9089-9100
9. Park, L. C. H., Albers, D. S., Xu, H., Lindsay, J. G., Beal, M. F., and Gibson, G. E. (2001) Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy. J. Neurosci. Res. 66, 1028-1034
10. Alam, Z. I., Jenner, A., Daniel, S. E., Lees, A. J., Cairns, N., Marsden, C. D., Jenner, P., and Halliwell, B. (1997) Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J. Neurochem. 69, 1196-1203 (Pubitemid 27364841)
11. Hüttemann, M., Lee, I., Pecinova, A., Pecina, P., Przyklenk, K., and Doan, J. W. (2008) Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease. J. Bioenerg. Biomembr. 40, 445-456
12. Foster, K. A., Galeffi, F., Gerich, F. J., Turner, D. A., Müller, M. (2006) Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration. Prog. Neurobiol. 79, 136-171 (Pubitemid 44255860)
13. Chen, L. B. (1988) Mitochondrial membrane potential in living cells. Annu. Rev. Cell Biol. 4, 155-181
14. Hackenbrock, C. R. (1966) Ultrastructural bases for metabolically linked mechanical activity in mitochondria. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria. J. Cell Biol. 30, 269-297
15. Rossignol, R., Gilkerson, R., Aggeler, R., Yamagata, K., Remington, S. J., and Capaldi, R. A. (2004) Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells. Cancer Res. 64, 985-993
16. Gottlieb, E., Armour, S. M., Harris, M. H., and Thompson, C. B. (2003) Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell Death Differ. 10, 709-717
17. Kuznetsov, A. V., Kunz, W. S., Saks, V., Usson, Y., Mazat, J. P., Letellier, T., Gellerich, F. N., and Margreiter, R. (2003) Cryopreservation of mitochondria and mitochondrial function in cardiac and skeletal muscle fibers. Anal. Biochem. 319, 296-303
18. Sheleg, S., Hixon, H., Cohen, B., Lowry, D., and Nedzved, M. (2008) Cardiac mitochondrial membrane stability after deep hypothermia using a xenon clathrate cryostasis protocol - an electron microscopy study. Int. J. Clin. Exp. Pathol. 1, 440-447
19. Gill-King, H. (1997) Chemical and ultrastructural aspects of decomposition. In Forensic Taphonomy: The Postmortem Fate of Human Remains (Haglund, W. D., ed) pp. 93-108, CRC Press, Boca Raton, FL, USA
20. 2+ thresholds determine cytochrome c release or permeability transition pore opening in brain mitochondria. FASEB J. 15, 565-567
21. Caspersen, C., Wang, N., Yao, J., Sosunov, A., Chen, X., Lustbader, J. W., Xu, H. W., Stern, D., McKhann, G., and Yan, S. D. (2005) Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease. FASEB J. 19, 2040-2041
22. Dennis, S. C., Lai, J. C., and Clark, J. B. (1977) Comparative studies on glutamate metabolism in synaptic and non-synaptic rat brain mitochondria. Biochem. J. 164, 727-736
23. Naga, K. K., Sullivan, P. G., and Geddes, J. W. (2007) High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition. J. Neurosci. 27, 7469-7475
24. Bijur, G. N., and Jope, R. S. (2003) Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation. J. Neurochem. 87, 1427-1435
25. Barksdale, K. A., and Bijur, G. N. (2009) The basal flux of Akt in the mitochondria is mediated by heat shock protein 90. J. Neurochem. 108, 1289-1299
26. Greiff, D., and Myers, M. (1961) Effect of dimethyl sulphoxide on the cryo-tolerance of mitochondria. Nature 190, 1202-1204
27. Greiff, D., Myers, M., and Privetera, C. A. (1961) The effects of glycerol, freezing and storage at low temperatures, and drying by vacuum sublimation on oxidative phosphorylation by mitochondrial suspensions. Biochim. Biophys. Acta 50, 233-242
28. Begley, J. G., Butterfield, D. A., Keller, J. N., Koppal, T., Drake, J., Mattson, M. P. (1998) Cryopreservation of rat cortical synaptosomes and analysis of glucose and glutamate transporter activities, and mitochondrial function. Brain Res. Brain. Res. Protoc. 3, 76-82 (Pubitemid 28481508)
29. Sakamoto, J. (1984) Effect of dimethylsulfoxide on ATP synthesis by mitochondrial soluble F1-ATPase. J. Biochem. 96, 483-487