Detection of herpes viruses in respiratory secretions of patients undergoing artificial ventilation

Journal of Medical Virology

Volumn 82, Issue 8, 2010, Pages 1406-1409

  Smith, C A ^a   Conroy, L T ^a   Pollock, M ^b   Ruddy, J ^b   Binning, A ^b   McCruden, E A B ^a,c  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b WESTERN INFIRMARY   (United Kingdom)

^c UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

Author keywords

CMV; EBV; HSV; ITU; PCR

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; AZATHIOPRINE; COLISTIN; CYCLOSPORIN; STEROID; TOBRAMYCIN; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; EPSTEIN BARR VIRUS; EPSTEIN BARR VIRUS INFECTION; FEMALE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORTALITY; NOSE SMEAR; POLYMERASE CHAIN REACTION; REAL TIME POLYMERASE CHAIN REACTION; SECRETIONS; THROAT CULTURE; VIRUS DETECTION; BODILY SECRETIONS; CRITICAL ILLNESS; GENETICS; HERPESVIRIDAE INFECTIONS; ISOLATION AND PURIFICATION; MIDDLE AGED; PREVALENCE; RESPIRATORY SYSTEM; SIMPLEXVIRUS; VERY ELDERLY; VIROLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BODILY SECRETIONS; CRITICAL ILLNESS; CYTOMEGALOVIRUS; DNA, VIRAL; FEMALE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 4, HUMAN; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PREVALENCE; RESPIRATION, ARTIFICIAL; RESPIRATORY SYSTEM; SIMPLEXVIRUS; YOUNG ADULT;

CYTOMEGALOVIRUS; HERPESVIRIDAE; HUMAN HERPESVIRUS 4; SIMPLEXVIRUS;

EID: 77956609079     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21794     Document Type: Article

References (13)

1. Bhatia M, Moochhala S. 2004. Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome. J Pathol 202:145-156. (Pubitemid 38208651)
2. Blue CE, Spiller OB, Blackbourn DJ. 2004. The relevance of complement to virus biology. Virology 319:176-184.
3. Bruynseels P, Jorens PG, Demey HE, Goossens H, Pattyn SR, Elseviers MM, Weyler J, Bossaert LL, Mentens Y, Ieven M. 2003. Herpes simplex virus in the respiratory tract of critical care patients: A prospective study. Lancet 362:1536-1541.
4. Daubin C, Vincent S, Vabret A, du Cheyron D, Parienti JJ, Ramakers M, Freymuth F, Charbonneau P. 2005. Nosocomial viral ventilator-associated pneumonia in the intensive care unit: A prospective cohort study. Intensive Care Med 31:1116-1122.
5. Jaber S, Chanques G, Borry J, Souche B, Verdier R, Perrigault PF, Eledjam JJ. 2005. Cytomegalovirus infection in critically ill patients: Associated factors and consequences. Chest 127:233-241.
6. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. 1985. APACHE11: A severity of disease classification system. Crit Care Med 13:818-829. (Pubitemid 15250137)
7. Linssen CF, Jacobs JA, Stelma FF, van Mook WN, Terporten P, Vink C, Drent M, Bruggeman CA, Smismans A. 2008. Herpes simplex virus load in bronchoalveolar lavage fluid is related to poor outcome in critically ill patients. Intensive Care Med 34:2202-2209.
8. Luyt CE, Combes A, Deback C, Aubriot-Lorton MH, Nieszkowska A, Trouillet JL, Capron F, Agut H, Gibert C, Chastre J. 2007. Herpes simplex virus lung infection in patients undergoing prolonged mechanical ventilation. Am J Respir Crit Care Med 175:935-942.
9. Ong GM, Lowry K, Mahajan S, Wyatt DE, Simpson C, O'Neill HJ, McCaughey C, Coyle PV. 2004. Herpes simplex type 1 shedding is associated with reduced hospital survival in patients receiving assisted ventilation in a tertiary referral intensive care unit. J Med Virol 72:121-125.
10. Scoular A, Gillespie G, Carman WF. 2002. Polymerase chain reaction for diagnosis of genital herpes in a genitourinary medicine clinic. Sex Transm Infect 78:21-25. (Pubitemid 34206309)
11. Simoons-Smit AM, Kraan EM, Beishuizen A, Strack van Schijndel RJ, Vandenbroucke-Grauls CM. 2006. Herpes simplex virus type 1 and respiratory disease in critically-ill patients: Real pathogen or innocent bystander? Clin Microbiol Infect 12:1050-1059.
12. Slifkin M, Doron S, Snydman DR. 2004. Viral prophylaxis in organ transplant patients. Drugs 64:2763-2792.
13. Verheij J, Groeneveld AB, Beishuizen A, van Lingen A, Simoons-Smit AM, van Schijndel RJ. 2004. Herpes simplex virus type 1 and normal protein permeability in the lungs of critically ill patients: A case for low pathogenicity? Crit Care 8:R139.