Limited functional capacity of microchimeric fetal hematopoietic progenitors acquired by mothers during pregnancy

Experimental Hematology

Volumn 38, Issue 10, 2010, Pages 852-853

  Leduc, Michele ^a   Guegan, Sarah ^a   Roy, Edwige ^a   Oster, Michele ^a   Aractingi, Selim ^a   Khosrotehrani, Kiarash ^a  

^a SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

STEM CELL FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; BONE MARROW; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; FETUS; FETUS CELL; HEMATOPOIETIC STEM CELL; LETTER; LYMPHOID CELL; MICROCHIMERISM; MOUSE; NONHUMAN; PHENOTYPIC PLASTICITY; PREGNANCY; PRIORITY JOURNAL; STEM CELL MOBILIZATION;

ANIMALS; ANTIGENS, CD34; CELL LINEAGE; CELL MOVEMENT; CHIMERISM; FEMALE; FETAL BLOOD; HEMATOPOIETIC STEM CELLS; HUMANS; LYMPHOCYTES; MATERNAL-FETAL EXCHANGE; PLACENTA; PREGNANCY; SPLEEN; THYMUS GLAND;

EID: 77956572429     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2010.06.009     Document Type: Letter

References (12)

1. Nguyen H.S., Dubernard G., Aractingi S., Khosrotehrani K. Feto-maternal cell trafficking: a transfer of pregnancy associated progenitor cells. Stem Cell Rev 2006, 2:111-116.
2. Evans P.C., Lambert N., Maloney S., Furst D.E., Moore J.M., Nelson J.L. Long-term fetal microchimerism in peripheral blood mononuclear cell subsets in healthy women and women with scleroderma. Blood 1999, 93:2033-2037.
3. Bianchi D.W., Zickwolf G.K., Weil G.J., Sylvester S., DeMaria M.A. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum. Proc Natl Acad Sci U S A 1996, 93:705-708.
4. Guetta E., Gordon D., Simchen M.J., Goldman B., Barkai G. Hematopoietic progenitor cells as targets for non-invasive prenatal diagnosis: detection of fetal CD34+ cells and assessment of post-delivery persistence in the maternal circulation. Blood Cells Mol Dis 2003, 30:13-21.
5. Adams K.M., Lambert N.C., Heimfeld S., et al. Male DNA in female donor apheresis and CD34-enriched products. Blood 2003, 102:3845-3847.
6. Osada H., Doi S., Fukushima T., Nakauchi H., Seki K., Sekiya S. Detection of fetal HPCs in maternal circulation after delivery. Transfusion 2001, 41:499-503.
7. Gekas C., Dieterlen-Lievre F., Orkin S.H., Mikkola H.K. The placenta is a niche for hematopoietic stem cells. Dev Cell 2005, 8:365-375.
8. Parant O., Dubernard G., Challier J.C., et al. CD34+ cells in maternal placental blood are mainly fetal in origin and express endothelial markers. Lab Invest 2009, 89:915-923.
9. Nguyen H.S., Oster M., Uzan S., Chareyre F., Aractingi S., Khosrotehrani K. Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells. Proc Natl Acad Sci U S A 2007, 104:1871-1876.
10. Nguyen Huu S., Oster M., Avril M.F., et al. Fetal microchimeric cells participate in tumour angiogenesis in melanomas occurring during pregnancy. Am J Pathol 2009, 174:630-637.
11. Khosrotehrani K., Johnson K.L., Guegan S., Stroh H., Bianchi D.W. Natural history of fetal cell microchimerism during and following murine pregnancy. J Reprod Immunol 2005, 66:1-12.
12. Khosrotehrani K., Leduc M., Bachy V., et al. Pregnancy allows the transfer and differentiation of fetal lymphoid progenitors into functional T and B cells in mothers. J Immunol 2008, 180:889-897.