Changes in brain FDG metabolism induced by acupuncture in healthy volunteers

Acta Radiologica

Volumn 51, Issue 8, 2010, Pages 947-952

  Park, Moon Seo ^a,b   Sunwoo, Yun Young ^b   Jang, Kyung Sool ^b   Han, Young Min ^b   Kim, Min Wook ^b   Maeng, Lee So ^b   Hong, Yeon Pyo ^a,b   Joo Hyun, J H ^c,d   Chung, Yong An ^b,c  

^a Chung Ang University   (South Korea)

^b Bupyeong gu   (South Korea)

^c The Catholic University of Korea   (South Korea)

^d The Catholic University of Korea   (South Korea)

Author keywords

F 18 FDG; Glucose metabolism; Limbic system; PET CT

Indexed keywords

ACUPOINTS; ACUPUNCTURE POINTS; BRAIN AREAS; COMPUTED TOMOGRAPHY; F-18 FDG; FLUORODEOXYGLUCOSE-POSITRON EMISSION TOMOGRAPHIES; FRONTAL LOBES; FUNCTIONAL BRAIN IMAGING; GLUCOSE METABOLISM; HUMAN BODIES; LIMBIC SYSTEM; MEAN AGES; PET-CT;

ACUPUNCTURE; BRAIN; COMPUTERIZED TOMOGRAPHY; GLUCOSE; METABOLISM; NEEDLES; STAINLESS STEEL;

POSITRON EMISSION TOMOGRAPHY;

DIAGNOSTIC AGENT; FLUORODEOXYGLUCOSE F 18; GLUCOSE; RADIOPHARMACEUTICAL AGENT;

ACUPUNCTURE; ADULT; ARTICLE; BRAIN; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HUMAN; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; PILOT STUDY; POSITRON EMISSION TOMOGRAPHY; RADIOGRAPHY; SCINTISCANNING;

ACUPUNCTURE POINTS; ADULT; BRAIN; FEMALE; FLUORODEOXYGLUCOSE F18; GLUCOSE; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 77956552328     PISSN: 02841851     EISSN: 16000455     Source Type: Journal    
DOI: 10.3109/02841851.2010.502541     Document Type: Article

References (23)

1. NIH Consensus Conference. Acupuncture. JAMA 1998;280: 1518-1524
2. Dougherty DD, Kong J, Webb M, Bonab AA, Fischman AJ, Gollub RL. A combined [11C]diprenorphine PET study and fMRI study of acupuncture analgesia. Behav Brain Res 2008;193:63-68
3. Biella G, Sotgiu ML, Pellegata G, Paulesu E, Castiglioni I, Fazio F. Acupuncture produces central activations in pain regions. Neuroimage 2001;14:60-66
4. Dhond RP, Kettner N, Napadow V. Neuroimaging acupuncture effects in the human brain. J Altern Complement Med 2007;13:603-616
5. Wu MT, Sheen JM, Chuang KH, Yang P, Chin SL, Tsai CY, et al. Neuronal specificity of acupuncture response: a fMRI study with electroacupuncture. Neuroimage 2002;16: 1028-1037
6. Yoo SS, Kerr CE, Park M, Im DM, Blinder RA, Park H, et al. Neural activities in human somatosensory cortical areas evoked by acupuncture stimulation. Complement Ther Med 2007;15:247-254
7. Fang J, Jin Z, Wang Y, Li K, Kong J, Nixon EE, et al. The salient characteristics of the central effects of acupuncture needling: limbic-paralimbic-neocortical network modulation. Hum Brain Mapp 2009;30:1196-1206
8. Deng G, Hou BL, Holodny AI, Cassileth BR. Functional magnetic resonance imaging (fMRI) changes and saliva production associated with acupuncture at LI-2 acupuncture point: a randomized controlled study. BMC Complement Altern Med 2008;8:37.
9. Vlassenko AG, Rundle MM, Mintun MA. Human brain glucose metabolism may evolve during activation: findings from a modified FDG PET paradigm. Neuroimage 2006;33:1036-1041
10. Jeong M, Tashiro M, Singh LN, Yamaguchi K, Horikawa E, Miyake M, et al. Functional brain mapping of actual car-driving using [18F]FDG-PET. Ann Nucl Med 2006; 20:623-628
11. Wong VC, Sun JG, Yeung DW. Pilot study of positron emission tomography (PET) brain glucose metabolism to assess the efficacy of tongue and body acupuncture in cerebral palsy. J Child Neurol 2006;21:456-462
12. Huang Y, Chen J, Htut WM, Lai X, Wik G. Acupuncture increases cerebral glucose metabolism in human vascular dementia. Int J Neurosci 2007;117:1029-1037
13. Stux G, Berman B, Pomeranz B. Basics of acupuncture. Berlin: Springer-Verlag; 2003.
14. Hui KK, Liu J, Makris N, Gollub RL, Chen AJ, Moore CI, et al. Acupuncture modulates the limbic system and subcortical gray structures of the human brain: evidence from fMRI studies in normal subjects. Hum Brain Mapp 2000;9:13-25.
15. Hui KK, Liu J, Marina O, Napadow V, Haselgrove C, Kwong KK, et al. The integrated response of the human cerebro-cerebellar and limbic systems to acupuncture stimulation at ST 36 as evidenced by fMRI. Neuroimage 2005;27:479-496
16. Kong J, Ma L, Gollub RL, Wei J, Yang X, Li D, et al. A pilot study of functional magnetic resonance imaging of the brain during manual and electroacupuncture stimulation of acupuncture point (LI-4 Hegu) in normal subjects reveals differential brain activation between methods. J Altern Complement Med 2002;8:411-419
17. Yan B, Li K, Xu J, Wang W, Li K, Liu H, et al. Acupointspecific fMRI patterns in human brain. Neurosci Lett 2005;383:236-240
18. Napadow V, Makris N, Liu J, Kettner NW, Kwong KK, Hui KK. Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI. Hum Brain Mapp 2005;24:193-205.
19. Zhang WT, Jin Z, Luo F, Zhang L, Zeng YW, Han JS. Evidence from brain imaging with fMRI supporting functional specificity of acupoints in humans. Neurosci Lett 2004;354:50-53
20. Fang JL, Krings T, Weidemann J, Meister IG, Thron A. Functional MRI in healthy subjects during acupuncture: different effects of needle rotation in real and false acupoints. Neuroradiology 2004;46:359-362
21. Le Bihan D, Jezzard P, Haxby J, Sadato N, Rueckert L, Mattay V. Functional magnetic resonance imaging of the brain. Ann Intern Med 1995;122:296-303.
22. Cherry SR, Phelps ME. Imaging brain function with positron emission tomography. In: Brain mapping: the methods. Second edition. San Diego: Academic Press; 2002. p. 485-511.
23. Streitberger K, Kleinhenz J. Introducing a placebo needle into acupuncture research. Lancet 1998;352:364-365