Synthesis and biochemical testing of 3-(carboxyphenylethyl)imidazo[2,1-f] [1,2,4]triazines as inhibitors of AMP deaminase

ACS Medicinal Chemistry Letters

Volumn 1, Issue 6, 2010, Pages 286-289

  Lindell, Stephen D ^a   Maechling, Simon ^a   Sabina, Richard L ^b  

^a BAYER CROPSCIENCE AG   (Germany)

^b OAKLAND UNIVERSITY WILLIAM BEAUMONT SCHOOL OF MEDICINE   (United States)

Author keywords

adenylate deaminase; AMP deaminase; AMPD inhibition; AMPD inhibitor; imidazotriazine

Indexed keywords

3 (CARBOXYPHENYLETHYL) IMIDAZO[2,1 F][1,2,4]TRIAZINE DERIVATIVE; 3 [2 (3 CARBOXY 5,6,7,8 TETRAHYDRONAPHTHYL)ETHYL]IMIDAZO[2,1 F][1,2,4]TRIAZINE; 3 [2 (3 CARBOXYPHENYL)ETHYL] 3,6,7,8 TETRAHYDROIMIDAZO[4,5 D][1,3]DIAZEPIN 8 OL; ADENOSINE MONOPHOSPHATE DEAMINASE; C RIBOSYL IMIDAZO[2,1 F][1,2,4]TRIAZINE DERIVATIVE; HYDROLASE INHIBITOR; TRIAZINE; UNCLASSIFIED DRUG;

ARABIDOPSIS; ARTICLE; DRUG ACTIVITY; DRUG INHIBITION; DRUG SYNTHESIS; ENTHALPY; ENZYME INHIBITION; HUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ARABIDOPSIS;

EID: 77956536452     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml100092a     Document Type: Article

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