Potential localization of putative stem/progenitor cells in human bulbar conjunctival epithelium

Journal of Cellular Physiology

Volumn 225, Issue 1, 2010, Pages 180-185

  Qi, Hong ^a,b   Zheng, Xiaofen ^a,c   Yuan, Xiaoyong ^a   Pflugfelder, Stephen C ^a   Li, De Quan ^a  

^a CULLEN EYE INSTITUTE   (United States)

^b PEKING UNIVERSITY   (China)

^c SHANXI EYE HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ENOLASE; BETA1 INTEGRIN; BREAST CANCER RESISTANCE PROTEIN; CYTOKERATIN 14; CYTOKERATIN 15; CYTOKERATIN 19; CYTOKERATIN 3; CYTOKERATIN 4; CYTOKERATIN 7; EPIDERMAL GROWTH FACTOR RECEPTOR; INVOLUCRIN; NERVE GROWTH FACTOR; NESTIN; NEURITE PROMOTING FACTOR; NEUROTROPHIN; PROTEIN P63; PROTEIN TYROSINE KINASE A; UVOMORULIN;

ADULT; AGED; ARTICLE; BASAL CELL; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONJUNCTIVA EPITHELIUM; CONTROLLED STUDY; CORNEA EPITHELIUM; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOLOCALIZATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CONJUNCTIVA; EPITHELIAL CELLS; EPITHELIUM, CORNEAL; HUMANS; KERATINS; LIMBUS CORNEAE; PROTEIN ISOFORMS; STEM CELLS; TISSUE DISTRIBUTION;

EID: 77956526545     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22215     Document Type: Article

References (44)

1. Abe K. 2000. Therapeutic potential of neurotrophic factors and neural stem cells against ischemic brain injury. J Cereb Blood Flow Metab 20:1393-1408.
2. Ang LP, Tan DTH, Beuerman RW, Lavker RM. 2004. Ocular surface epithelial stem cells: Implications for ocular surface homeostasis. In: Pflugfelder SC, Beuerman RW, Stern ME, editors. Dry eye and ocular surface disorders. New York, NY: Marcel Dekker, Inc. pp 225-246.
3. Banks-Schlegel S, Green H. 1981. Involucrin synthesis and tissue assembly by keratinocytes in natural and cultured human epithelia. J Cell Biol 90:732-737. (Pubitemid 12254931)
4. Barnard Z, Apel AJG, Harkin DG. 2001. Phenotypic analyses of limbal epithelial cell cultures derived from donor corneoscleral rims. Clin Exp Ophthalmol 29:138-142.
5. Braydich-Stolle L, Nolan C, Dym M, Hofmann MC. 2005. Role of glial cell line-derived neurotrophic factor in germ-line stem cell fate. Ann NY Acad Sci 1061:94-99. (Pubitemid 43211589)
6. Buageaw A, Sukhwani M, Ben Yehudah A, Ehmcke J, Rawe VY, Pholpramool C, Orwig KE, Schlatt S. 2005. GDNF family receptor alpha1 phenotype of spermatogonial stem cells in immature mouse testes. Biol Reprod 73:1011-1016.
7. Chao MV, Rajagopal R, Lee FS. 2006. Neurotrophin signalling in health and disease. Clin Sci (Lond) 110:167-173.
8. Chen Z, de Paiva CS, Luo L, Kretzer FL, Pflugfelder SC, Li D-Q. 2004. Characterization of putative stem cell phenotype in human limbal epithelia. Stem Cells 22:355-366. (Pubitemid 38736619)
9. Collin C, Ouhayoun JP, Grund C, Franke WW. 1992. Suprabasal marker proteins distinguishing keratinizing squamous epithelia: Cytokeratin 2 polypeptides of oral masticatory epithelium and epidermis are different. Differentiation 51:137-148.
10. Diebold Y, Rios JD, Hodges RR, Rawe I, Dartt DA. 2001. Presence of nerves and their receptors in mouse and human conjunctival goblet cells. Invest Ophthalmol Vis Sci 42:2270-2282. (Pubitemid 32848856)
11. Fuchs E, Chan YM, Paller AS, Yu QC. 1994. Cracks in the foundation: Keratin filaments and genetic disease. Trends Cell Biol 4:321-326.
12. Hsueh YJ, Wang DY, Cheng CC, Chen JK. 2004. Age-related expressions of p63 and other keratinocyte stem cell markers in rat cornea. J Biomed Sci 11:641-651.
13. Huang EJ, Reichardt LF. 2003. Trk receptors: Roles in neuronal signal transduction. Annu Rev Biochem 72:609-642. (Pubitemid 36930455)
14. Huang AJ, Tseng SC, Kenyon KR. 1988. Morphogenesis of rat conjunctival goblet cells. Invest Ophthalmol Vis Sci 29:969-975.
15. Kao WW, Liu CY. 2003. The use of transgenic and knock-out mice in the investigation of ocular surface cell biology. Ocul Surf 1:5-19.
16. Kasper M. 1991. Heterogeneity in the immunolocalization of cytokeratin specific monoclonal antibodies in the rat eye: Evaluation of unusual epithelial tissue entities. Histochemistry 95:613-620.
17. Kasper M. 1992. Cytokeratins in intracranial and intraspinal tissues. Adv Anat Embryol Cell Biol 126:1-82.
18. Krenzer KL, Freddo TF. 1997. Cytokeratin expression in normal human bulbar conjunctiva obtained by impression cytology. Invest Ophthalmol Vis Sci 38:142-152.
19. Lambiase A, Bonini S, Micera A, Rama P, Bonini S, Aloe L. 1998. Expression of nerve growth factor receptors on the ocular surface in healthy subjects and during manifestation of inflammatory diseases. Invest Ophthalmol Vis Sci 39:1272-1275.
20. Lane EB, McLean WH. 2004. Keratins and skin disorders. J Pathol 204:355-366.
21. Liu S, Li J, Tan DT, Beuerman RW. 2007. The eyelid margin: A transitional zone for 2 epithelial phenotypes. Arch Ophthalmol 125:523-532.
22. Maness LM, Kastin AJ, Weber JT, Banks WA, Beckman BS, Zadina JE. 1994. The neurotrophins and their receptors: Structure, function, and neuropathology. Neurosci Biobehav Rev 18:143-159. (Pubitemid 24058931)
23. Mischke D. 1998. The complexity of gene families involved in epithelial differentiation. Keratin genes and the epidermal differentiation complex. Subcell Biochem 31:71-104.
24. Moll R, Franke WW, Schiller DL, Geiger B, Krepler R. 1982. The catalog of human cytokeratins. Patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24.
25. Nakamura T, Endo KI, Kinoshita S. 2006. Identification of human oral keratinocyte stem/progenitor cells by neurotrophin receptor p75 and the role of neurotrophin/p75 signaling. Stem Cells 25:628-638.
26. Niles LP, Armstrong KJ, Rincon Castro LM, Dao CV, Sharma R, McMillan CR, Doering LC, Kirkham DL. 2004. Neural stem cells express melatonin receptors and neurotrophic factors: Colocalization of the MT1 receptor with neuronal and glial markers. BMC Neurosci 5:41.
27. Okumura T, Shimada Y, Imamura M, Yasumoto S. 2003. Neurotrophin receptor p75(NTR) characterizes human esophageal keratinocyte stem cells in vitro. Oncogene 22:4017-4026. (Pubitemid 36819642)
28. Pellegrini G, Golisano O, Paterna P, Lambiase A, Bonini S, Rama P, De Luca M. 1999. Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface. J Cell Biol 145:769-782.
29. Pitz S, Moll R. 2002. Intermediate-filament expression in ocular tissue. Prog Retin Eye Res 21:241-262.
30. Porter RM, Lunny DP, Ogden PH, Morley SM, McLean WH, Evans A, Harrison DL, Rugg EL, Lane EB. 2000. K15 expression implies lateral differentiation within stratified epithelial basal cells. Lab Invest 80:1701-1710.
31. Qi H, Chuang EY, Yoon KC, de Paiva CS, Shine HD, Jones DB, Pflugfelder SC, Li DQ. 2007. Patterned expression of neurotrophic factors and receptors in human limbal and corneal regions. Mol Vis 13:1934-1941.
32. Rios JD, Ghinelli E, Gu J, Hodges RR, Dartt DA. 2007. Role of neurotrophins and neurotrophin receptors in rat conjunctival goblet cell secretion and proliferation. Invest Ophthalmol Vis Sci 48:1543-1551. (Pubitemid 351261337)
33. Saarma M, Sariola H. 1999. Other neurotrophic factors: Glial cell line-derived neurotrophic factor (GDNF). Microsc Res Tech 45:292-302.
34. Schermer A, Galvin S, Sun T-T. 1986. Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol 103:49-62.
35. Schlotzer-Schrehardt U, Kruse FE. 2005. Identification and characterization of limbal stem cells. Exp Eye Res 81:247-264. (Pubitemid 41208160)
36. Steinert PM. 1993. Structure, function, and dynamics of keratin intermediate filaments. J Invest Dermatol 100:729-734.
37. Stepp MA, Zieske JD. 2005. The corneal epithelial stem cell niche. Ocul Surf 3:15-26.
38. Touhami A, Grueterich M, Tseng SC. 2002. The role of NGF signaling in human limbal epithelium expanded by amniotic membrane culture. Invest Ophthalmol Vis Sci 43:987-994. (Pubitemid 34258265)
39. Tseng SC, Jarvinen MJ, Nelson WG, Huang JW, Woodcock-Mitchell J, Sun TT. 1982. Correlation of specific keratins with different types of epithelial differentiation: Monoclonal antibody studies. Cell 30:361-372.
40. Watt FM, Green H. 1981. Involucrin synthesis is correlated with cell size in human epidermal cultures. J Cell Biol 90:738-742.
41. Wei Z-G, Wu R-L, Lavker RM, Sun T-T. 1993. In vitro growth and differentiation of rabbit bulbar, fornix, and palpebral conjunctival epithelia. Implication on conjunctival epithelial transdifferentiation and stem cells. Invest Ophthalmol Vis Sci 34:1814-1828.
42. Wei ZG, Cotsarelis G, Sun TT, Lavker RM. 1995. Label-retaining cells are preferentially located in fornical epithelium: Implications on conjunctival epithelial homeostasis. Invest Ophthalmol Vis Sci 36:236-246.
43. Wei Z-G, Sun T-T, Lavker RM. 1996. Rabbit conjunctival and corneal epithelial cells belong to two separate lineages. Invest Ophthalmol Vis Sci 37:523-533.
44. Yoshida S, Shimmura S, Kawakita T, Miyashita H, Den S, Shimazaki J, Tsubota K. 2006. Cytokeratin 15 can be used to identify the limbal phenotype in normal and diseased ocular surfaces. Invest Ophthalmol Vis Sci 47:4780-4786.