Dercum's Disease: An Unusual Presentation

Pain Medicine

Volumn 11, Issue 9, 2010, Pages 1430-1434

  Kosseifi, Semann ^a   Anaya, Ervin ^b   Dronovalli, Goutham ^b   Leicht, Stuart ^b  

^a Wellmont Hospital   (United Kingdom)

^b East Tennessee State University   (United States)

Author keywords

Adiposis Dolorosa; Dercum's Disease; Inflammation; Subcutaneous Fat

Indexed keywords

ANALGESIC AGENT; AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; GABAPENTIN; HYDROXYCHLOROQUINE; LIDOCAINE; METHOTREXATE; MEXILETINE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; SEROTONIN UPTAKE INHIBITOR;

ACTINIC KERATOSIS; ADIPOSIS DOLOROSA; AGED; ALLODYNIA; ANALGESIA; ARTICLE; BURNING SENSATION; CASE REPORT; CLINICAL EXAMINATION; DEPRESSION; DIFFERENTIAL DIAGNOSIS; DISEASE DURATION; ERYTHEMA; FEMALE; FOLLOW UP; HIP; HISTOPATHOLOGY; HUMAN; INJECTION; LABORATORY TEST; LEG PAIN; LIPOSUCTION; OUTCOME ASSESSMENT; OUTPATIENT DEPARTMENT; PATIENT EDUCATION; POSTMENOPAUSE; PRESCRIPTION; PROGNOSIS; PUNCH BIOPSY; RISK BENEFIT ANALYSIS; SKIN ALLERGY; SKIN DEFECT; SWELLING; TRANSDERMAL PATCH;

EID: 77956509759     PISSN: 15262375     EISSN: 15264637     Source Type: Journal    
DOI: 10.1111/j.1526-4637.2010.00828.x     Document Type: Article

References (23)

1. Dercum FX. Three cases of hitherto unclassified affection resembling in its grosser aspects obesity, but associated with special nervous symptoms, adiposis dolorosa. Am J Med Sci 1892, 104:521-35.
2. Brorson H, Fagher B. [Dercum's disease. Fatty tissue rheumatism caused by immune defense reaction?]. Lakartidningen 1996, 93(15):1430-6.
3. Wortham NC, Tomlinson IP. Dercum's disease. Skinmed 2005, 4(3):157-62.
4. Cantu JM, Ruiz-Barquin E, Jimenez M. Autosomal dominant inheritance in adiposis dolorosa (Dercum's disease). Humangenetik 1973, 18(1):89-91.
5. Gamez J, Playan A, Andreu AL. Familial multiple symmetric lipomatosis associated with the A8344G mutation of mitochondrial DNA. Neurology 1998, 51(1):258-60.
6. Campen R, Mankin H, Louis DN. Familial occurrence of adiposis dolorosa. J Am Acad Dermatol 2001, 44(1):132-6.
7. Silvestri G, Ciafaloni E, Santorelli FM. Clinical features associated with the A→G transition at nucleotide 8344 of mtDNA (" MERRF mutation" ). Neurology 1993, 43(6):1200-6.
8. Leites SM, Davtian NK, Emanuel VI. [Pathophysiological characteristics of adipose tissue in Dercum's syndrome]. Patol Fiziol Eksp Ter 1972, 16(1):47-51.
9. Skagen K, Petersen P, Kastrup J. The regulation of subcutaneous blood flow in patient with Dercum's disease. Acta Derm Venereol 1986, 66(4):337-9.
10. Blomstrand R, Juhlin L, Nordenstam H. Adiposis dolorosa associated with defects of lipid metabolism. Acta Derm Venereol 1971, 51(4):243-50.
11. Greenbaum SS, Varga J. Corticosteroid-induced juxta-articular adiposis dolorosa. Arch Dermatol 1991, 127(2):231-3.
12. Brodovsky S, Westreich M, Leibowitz A. Adiposis dolorosa (Dercum's disease): 10-year follow-up. Ann Plast Surg 1994, 33(6):664-8.
13. Fagher B, Monti M, Nilsson-Ehle P. Fat-cell heat production, adipose tissue fatty acids, lipoprotein lipase activity and plasma lipoproteins in adiposis dolorosa. Clin Sci (Lond) 1991, 81(6):793-8.
14. Amine B, Leguilchard F, Benhamou CL. Dercum's disease (adiposis dolorosa): A new case-report. Joint Bone Spine 2004, 71(2):147-9.
15. Donhauser G, Vieluf D, Ruzicka T. [Benign symmetric Launois-Bensaude type III lipomatosis and Bureau-Barriere syndrome]. Hautarzt 1991, 42(5):311-4.
16. Campen RB, Sang CN, Duncan LM. Case records of the Massachusetts General Hospital. Case 25-2006. A 41-year-old woman with painful subcutaneous nodules. N Engl J Med 2006, 355(7):714-22.
17. Palmer ED. Dercum's disease: Adiposis dolorosa. Am Fam Physician 1981, 24(5):155-7.
18. Iwane T, Maruyama M, Matsuki M. Management of intractable pain in adiposis dolorosa with intravenous administration of lidocaine. Anesth Analg 1976, 55(2):257-9.
19. Petersen P, Kastrup J. Dercum's disease (adiposis dolorosa). Treatment of the severe pain with intravenous lidocaine. Pain 1987, 28(1):77-80.
20. Steiner J, Schiltz K, Heidenreich F. [Lipomatosis dolorosa-a frequently overlooked disease picture]. Nervenarzt 2002, 73(2):183-7.
21. De Silva M, Earley MJ. Liposuction in the treatment of juxta-articular adiposis dolorosa. Ann Rheum Dis 1990, 49(6):403-4.
22. DeFranzo AJ, Hall JH, Herring SM. Adiposis dolorosa (Dercum's disease): Liposuction as an effective form of treatment. Plast Reconstr Surg 1990, 85(2):289-92.
23. Singal A, Janiga JJ, Bossenbroek NM. Dercum's disease (adiposis dolorosa): A report of improvement with infliximab and methotrexate. J Eur Acad Dermatol Venereol 2007, 21(5):717.