Superinhibitory phospholamban mutants compete with Ca2+ for binding to SERCA2a by stabilizing a unique nucleotide-dependent conformational state

Journal of Biological Chemistry

Volumn 285, Issue 37, 2010, Pages 28540-28552

  Akin, Brandy L ^a   Chen, Zhenhui ^a   Jones, Larry R ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CONFORMATIONS; CROSSLINKING; NUCLEOTIDES; PUMPS;

ATP-ASE ACTIVITY; BINDING INTERACTION; CHEMICAL CROSS-LINKING; CONFORMATIONAL STATE; CROSS-LINKABLE; FREE STATE; INHIBITORY STRENGTH; NANOMOLAR; PHOSPHOLAMBAN; STABLE COMPLEXES; THAPSIGARGINS;

CALCIUM;

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM ION; MUTANT PROTEIN; PHOSPHOLAMBAN; PHOSPHOLAMBAN 3; PHOSPHOLAMBAN 4; PHOSPHOLAMBAN N30C; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2A; THAPSIGARGIN; UNCLASSIFIED DRUG; VANADIC ACID; ADENOSINE TRIPHOSPHATE; CALCIUM; CALCIUM BINDING PROTEIN; ENZYME INHIBITOR; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CALCIUM BINDING; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS LINKING; INHIBITION KINETICS; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; AMINO ACID SUBSTITUTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DOG; DRUG EFFECTS; GENETICS; METABOLISM; MISSENSE MUTATION; SPODOPTERA;

ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; CELL LINE; DOGS; ENZYME INHIBITORS; MUTATION, MISSENSE; PROTEIN BINDING; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SPODOPTERA; THAPSIGARGIN; VANADATES;

EID: 77956502772     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.151779     Document Type: Article

References (49)

1. Simmerman, H. K., and Jones, L. R. (1998) Physiol. Rev. 78, 921-947
2. MacLennan, D. H., and Kranias, E. G. (2003) Nat. Rev. Mol. Cell Biol. 4, 566-577
3. Kimura, Y., Kurzydlowski, K., Tada, M., and MacLennan, D. H. (1997) J. Biol. Chem. 272, 15061-16064
4. Autry, J. M., and Jones, L. R. (1997) J. Biol. Chem. 272, 15872-15880
5. Cornea, R. L., Jones, L. R., Autry, J. M., and Thomas, D. D. (1997) Biochemistry 36, 2960-2967
6. Reddy, L. G., Jones, L. R., and Thomas, D. D. (1999) Biochemistry 38, 3954-3962
7. Jones, L. R., Cornea, R. L., and Chen, Z. (2002) J. Biol. Chem. 277, 28319-28329
8. Robia, S. L., Campbell, K. S., Kelly, E. M., Hou, Z., Winters, D. L., and Thomas, D. D. (2007) Circ. Res. 101, 1123-1129
9. Kelly, E. M., Hou, Z., Bossuyt, J., Bers, D. M., and Robia, S. L. (2008) J. Biol. Chem. 283, 12202-12211
10. Chen, Z., Stokes, D. L., Rice, W. J., and Jones, L. R. (2003) J. Biol. Chem. 278, 48348-48356
11. Chen, Z., Akin, B. L., and Jones, L. R. (2007) J. Biol. Chem. 282, 20968-20976
12. Chen, Z., Akin, B. L., and Jones, L. R. (2010) J. Biol. Chem. 285, 3253-3260
13. Inesi, G., Kurzmack, M., Coan, C., and Lewis, D. E. (1980) J. Biol. Chem. 255, 3025-3031
14. Zhang, Z., Lewis, D., Strock, C., Inesi, G., Nakasako, M., Nomura, H., and Toyoshima, C. (2000) Biochemistry 39, 8758-8767
15. Kimura, Y., Asahi, M., Kurzydlowski, K., Tada, M., and MacLennan, D. H. (1998) J. Biol. Chem. 273, 14238-14241
16. Haghighi, K., Schmidt, A. G., Hoit, B. D., Brittsan, A. G., Yatani, A., Lester, J. W., Zhai, J., Kimura, Y., Dorn, G. W., 2nd, MacLennan, D. H., and Kranias, E. G. (2001) J. Biol. Chem. 276, 24145-24152
17. Chen, Z., Akin, B. L., Stokes, D. L., and Jones, L. R. (2006) J. Biol. Chem. 281, 14163-14172
18. Sagara, Y., Fernandez-Belda, F., de Meis, L., and Inesi, G. (1992) J. Biol. Chem. 267, 12606-12613
19. Pick, U. (1982) J. Biol. Chem. 257, 6111-6119
20. Reddy, L. G., Cornea, R. L., Winters, D. L., McKenna, E., and Thomas, D. D. (2003) Biochemistry 42, 4585-4592
21. Trieber, C. A., Douglas, J. L., Afara, M., and Young, H. S. (2005) Biochemistry 44, 3289-3297
22. Waggoner, J. R., Huffman, J., Froehlich, J. P., and Mahaney, J. E. (2007) Biochemistry 46, 1999-2009
23. Trieber, C. A., Afara, M., and Young, H. S. (2009) Biochemistry 48, 9287-9296
24. McIntosh, D. B., Woolley, D. G., MacLennan, D. H., Vilsen, B., and Andersen, J. P. (1999) J. Biol. Chem. 274, 25227-25236
25. Marchand, A., Winther, A. M., Holm, P. J., Olesen, C., Montigny, C., Arnou, B., Champeil, P., Clausen, J. D., Vilsen, B., Andersen, J. P., Nissen, P., Jaxel, C., Møller, J. V., and le Maire, M. (2008) J. Biol. Chem. 283, 14867-14882
26. Cantilina, T., Sagara, Y., Inesi, G., and Jones, L. R. (1993) J. Biol. Chem. 267, 17018-17025
27. Jones, L. R., Besch, H. R., Jr., and Watanabe, A. M. (1978) J. Biol. Chem. 253, 1643-1653
28. Cornea, R. L., Autry, J. M., Chen, Z., and Jones, L. R. (2000) J. Biol. Chem. 275, 41487-41494
29. Jones, L. R. (1979) Biochim. Biophys. Acta 557, 230-242
30. Maruyama, K., and MacLennan, D. H. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 3314-3318
31. Lytton, J., Westlin, M., and Hanley, M. R. (1991) J. Biol. Chem. 266, 17067-17071
32. Lacapère, J. J., Bennett, N., Dupont, Y., and Guillain, F. (1990) J. Biol. Chem. 265, 348-353
33. DeJesus, F., Girardet, J. L., and Dupont, Y. (1993) FEBS Lett. 332, 229-232
34. Jensen, A. M., Sørensen, T. L., Olesen, C., Møller, J. V., and Nissen, P. (2006) EMBO J. 25, 2305-2314
35. Montigny, C., Picard, M., Lenoir, G., Gauron, C., Toyoshima, C., and Champeil, P. (2007) Biochemistry 46, 15162-15174
36. Toyoshima, C., Asahi, M., Sugita, Y., Khanna, R., Tsuda, T., and MacLennan, D. H. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 467-472
37. Mahaney, J. E., Autry, J. M., and Jones, L. R. (2000) Biophys. J. 78, 1306-1323
38. Bers, D. M. (2000) Circ. Res. 87, 275-281
39. Sham, J. S., Jones, L. R., and Morad, M. (1991) Am. J. Physiol. 261, H1344-H1349
40. Watanabe, T., Lewis, D., Nakamoto, R., Kurzmack, M., Fronticelli, C., and Inesi, G. (1981) Biochemistry 20, 6617-6625
41. Montigny, C., Arnou, B., Marchal, E., and Champeil, P. (2008) Biochemistry 47, 12159-12174
42. Inesi, G., Lewis, D., and Murphy, A. J. (1984) J. Biol. Chem. 259, 996-1003
43. Masuda, H., and de Meis, L. (1973) Biochemistry 12, 4581-4585
44. Andersen, J. P., and Møller, J. V. (1985) Biochim. Biophys. Acta 815, 9-15
45. Toyoshima, C. (2008) Arch. Biochem. Biophys. 476, 3-11
46. Fortea, M. I., Soler, F., and Fernandez-Belda, F. (2001) J. Biol. Chem. 276, 37266-37272
47. Inesi, G., Lewis, D., Toyoshima, C., Hirata, A., and de Meis, L. (2008) J. Biol. Chem. 283, 1189-1196
48. Wictome, M., Henderson, I., Lee, A. G., and East, J. M. (1992) Biochem. J. 283, 525-529
49. Moncoq, K., Trieber, C. A., and Young, H. S. (2007) J. Biol. Chem. 282, 9748-9757