Relationship between IgG titers and opsonocytophagocytic activity of anti-pneumococcal antibodies after immunization with the 7-valent conjugate vaccine in allogeneic stem cell transplant

Bone Marrow Transplantation

Volumn 45, Issue 9, 2010, Pages 1423-1426

  Cordonnier, C ^a   Labopin, M ^b   Jansen, K U ^c   Pride, M ^c   Chesnel, V ^b   Bonnet, E ^d   Einsele, H ^e   Ljungman, P ^f  

^a HENRI MONDOR HOSPITAL   (France)

^b HÔPITAL SAINT ANTOINE   (France)

^c WYETH RESEARCH   (United States)

^d Wyeth Pharma   (France)

^e UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

allo SCT; conjugate pneumococcal vaccine; opsonocytophagocytic activity

Indexed keywords

BACTERIUM ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; PNEUMOCOCCUS VACCINE;

ADOLESCENT; ADULT; AGED; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EARLY INTERVENTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMATOLOGIC DISEASE; HUMAN; IMMUNIZATION; MALE; MULTICENTER STUDY; OPSONIZATION; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THERAPY DELAY; TREATMENT RESPONSE;

ADOLESCENT; ADULT; BONE MARROW DISEASES; CHILD; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNIZATION SCHEDULE; IMMUNOGLOBULIN G; MIDDLE AGED; OPSONIN PROTEINS; PHAGOCYTOSIS; PNEUMOCOCCAL VACCINES; TRANSPLANTATION, HOMOLOGOUS; VACCINES, CONJUGATE; YOUNG ADULT;

EID: 77956491037     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2009.364     Document Type: Article

References (15)

1. Engelhard D, Cordonnier C, Shaw PJ, Parkkali T, Guenther C, Martino R et al. Early and late invasive pneumococcal infection following stem cell transplantation: a European Bone Marrow Transplantation survey. Br J Haematol 2002; 117: 444-450.
2. Hammarstrom V, Pauksen K, Azinge J, Oberg G LP, Oberg G, Ljungman P. Pneumococcal immunity and response to immunization with pneumococcal vaccine in bone marrow transplant patients: the influence of graft versus host reaction. Support Care Cancer 1993; 1: 195-199.
3. Shinefield HR, Black S, Ray P, Chang I, Lewis N, Fireman B et al. Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and tolders. Pediatr Infect Dis 1999; 18: 757-763.
4. Kumar D, Chen MH, Welsh B, Siegal D, Cobos I, Messner HA et al. A randomized, double blind trial of pneumococcal vaccination in adult allogeneic stem cell transplant donors and recipients. Clin Infect Dis 2007; 45: 1576-1582.
5. Molrine D, Antin JH, Guinan EC, Soiffer RJ, MacDonald C, Malley R et al. Donor immunization with pneumococcal conjugate vaccine and early protective antibody responses following allogeneic hematopoietic stem cell transplantation. Blood 2003; 101: 831-836.
6. Meisel R, Kuypers L, Dirksen U, Schubert R, Gruhn B, Strauss G et al. Pneumococcal conjugate vaccine provides early protective antibody responses in children after related and unrelated allogeneic stem cell transplantation. Blood 2007; 109: 2322-2326.
7. Cordonnier C, Labopin M, Chesnel V, Ribaud P, De La Camara R, Martino R et al. Randomized study of early versus late immunization with pneumococcal conjugate vaccine after allogeneic stem cell transplantation. Clin Infect Dis 2009; 48: 1392-1401.
8. Nahm MH, Romero-Steiner S. Functional assays for pneumo-coccal antibody. In GR Siber (ed). Pneumovoccal Vaccines: The Impact of Conjugate Vaccines. ASM Press: Washington DC, 2008.
9. World Organization ECoBS. Pneumococcal conjugate vaccine: recommendations for production and quality control of pneumococcal conjugate vaccines.
10. Concepcion NF, Frasch CE. Pneumococcal type 22f poly-saccharide absorption improves the specificity of a pneumo-coccal-polysaccharide enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol 2001; 8: 266-272.
11. Siber GR, Chang I, Baker S, Fernsten P, O'Brien KL, Santosham M et al. Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies. Vaccine 2007; 25: 3816-3826.
12. Hu BT, Yu X, Jones TR, Kirch C, Harris S, Hildreth SW et al. Approach to validating an opsonophagocytic assay for Streptococcus pneumoniae. Clin Diagn Lab Immunol 2005; 12: 287-295.
13. Ljungman P, Cordonnier C, Einsele H, Englund J, Machado CM, Storek J et al. Vaccination of hematopoietic cell transplant patients. Bone Marrow Transplant 2009; 44: 521-526.
14. Romero-Steiner S, Musher DM, Cetron MS, Pais LB, Groover JE, Fiore AE et al. Reduction in functional antibody activity against Streptococcus pneumoniae in vaccinated elderly individuals highly correlates with decreased IgG antibody avidity. Clin Infect Dis 1999; 29: 281-284.
15. Feikin DRCM, Elie MB, Goetz JL, Lennox JL, Carlone GM, Romero-Steiner S et al. Randomized trial of the quantitative and functional antibody responses to a 7-valent pneumococcal conjugate vaccine and/or 23-valent polysaccharide vaccine among HIV-infected adults. Vaccine 2001; 20: 545-553.