Review: Omega-3 and memory function: To eat or not to eat

American Journal of Alzheimer's Disease and other Dementias

Volumn 25, Issue 6, 2010, Pages 479-482

  Itua, Imose ^a   Naderali, Ebrahim K ^a  

^a LIVERPOOL HOPE UNIVERSITY   (United Kingdom)

Author keywords

Alzheimers disease; cognitive impairment; dietary fatty acids; docosahexaenoic acid; omega 3

Indexed keywords

DOCOSAHEXAENOIC ACID; OMEGA 3 FATTY ACID; PLACEBO;

ALZHEIMER DISEASE; CENTRAL NERVOUS SYSTEM; COGNITIVE DEFECT; DEMENTIA; DIET SUPPLEMENTATION; DIETARY INTAKE; DISEASE COURSE; DRUG MECHANISM; HUMAN; LIFESTYLE; MEMORY; NEUROPROTECTION; NONHUMAN; NUTRITIONAL VALUE; PREVALENCE; REVIEW;

EID: 77956481121     PISSN: 15333175     EISSN: None     Source Type: Journal    
DOI: 10.1177/1533317510376943     Document Type: Review

References (41)

1. Hooijmans CR, Kiliaan AJ Fatty acids, lipid metabolism and Alzheimer pathology. Eur J Pharmacol. 2008 ; 585 (1). 176-196.
2. Naderali EK Obesity and cardiovascular dysfunction: a role for resveratrol? Obes Res Clin Pract. 2009 ; 3 (1). 45-52.
3. Weih W., Wiltfang J., Kornhuber J. Non-pharmacologic prevention of Alzheimers disease: nutritional and life-style risk factors. J Neural Transm. 2007 ; 114 (9). 1187-1197.
4. Forsyth E., Ritzline PD An overview of the etiology, diagnosis, and treatment of Alzheimer disease. Phys Ther. 1998 ; 78 (12). 1325-1331.
5. Albanese E., Banerjee S., Dhanasiri S., et al. Dementia UK A report to the Alzheimers Society on the prevalence and economic cost of dementia in the UK produced by Kings College London and London School of Economics. London, UK: Alzheimers Society ; 2007.
6. McLean CA, Cherny RA, Fraser FW, et al. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimers disease. Ann Neurol. 1999 ; 46 (6). 860-866.
7. Chui DH, Tanahashi H., Ozawa K., et al. Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. Nat Med. 1999 ; 5 (5). 560-564.
8. Evin G., Weidemann A. Biogenesis and metabolism of Alzheimers disease Abeta amyloid peptides. Peptides. 2002 ; 23 (7). 1285-1297.
9. Barghorn S., Nimmrich V., Striebinger A., et al. Globular amyloid beta-peptide oligomer: a homogenous and stable neuropathological protein in Alzheimers disease. J Neurochem. 2005 ; 95 (3). 834-847.
10. Lacor PN, Buniel MC, Furlow PW, et al. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimers disease. J Neurosci. 2007 ; 27 (4). 796-807.
11. Naderali EK, Ratcliffe SH, Dale MC Obesity and Alzheimers disease: a link between body weight and cognitive function in old age. Am J Alzheimers Dis Other Demen. 2009 ; 24 (6). 445-449.
12. Gustaw-Rothenberg K. Dietary patterns associated with Alzheimers disease: population based study. Int J Environ Res Public Health. 2009 ; 6 (4). 1335-1340.
13. Scarmeas N., Stern Y., Mayeux R., Manly JJ, Schupf N., Luchsinger JA Mediterranean diet and mild cognitive impairment. Arch Neurol. 2009 ; 66 (2). 216-225.
14. Barberger-Gateau P., Raffaitin C., Letenneur L., et al. Dietary patterns and risk of dementia: the Three-City cohort study. Neurology. 2007 ; 69 (20). 1921-1930.
15. Scarmeas N., Luchsinger JA, Schupf N., et al. Physical activity, diet, and risk of Alzheimer disease. JAMA. 2009 ; 302 (6). 627-637.
16. Scarmeas N., Stern Y., Mayeux R., Luchsinger JA Mediterranean diet, Alzheimer disease, and vascular mediation. Arch Neurol. 2006 ; 63 (12). 1709-1717. (Pubitemid 44925078)
17. Florent-Bechard S., Desbene C., Garcia P., et al. The essential role of lipids in Alzheimers disease. Biochimie. 2009 ; 91 (6). 804-809.
18. Youssef I., Florent-Bechard S., Malaplate-Armand C., et al. N-truncated amyloid-2 oligomers induce learning impairment and neuronal apoptosis. Neurobiol Aging. 2008 ; 29 (9). 1319-1333.
19. Calder PC Polyunsaturated fatty acids, inflammation, and immunity. Lipids. 2001 ; 36 (9). 1007-1024.
20. Vedin I., Cederholm T., Freund-Levi Y., et al. Reduced prostaglandin F2 alpha release from blood mononuclear leukocytes after oral supplementation of omega3 fatty acids: the OmegAD study. J Lipid Res. 2010 ; 51 (5). 1179-1185.
21. Robinson JG, Ijioma N., Harris W. Omega-3 fatty acids and cognitive function in women. Womens Health (Lond Engl). 2010 ; 6 (1). 119-134.
22. Wurtman RJ, Ulus IH, Cansev M., Watkins CJ, Wang L., Marzloff G. Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally. Brain Res. 2006 ; 1088 (1). 83-92.
23. Wurtman RJ, Cansev M., Sakamoto T., Ulus IH Use of phosphatide precursors to promote synaptogenesis. Annu Rev Nutr. 2009 ; 29: 59-87.
24. Arendash GW, Jensen MT, Salem N. Jr, et al. A diet high in omega-3 fatty acids does not improve or protect cognitive performance in Alzheimers transgenic mice. Neuroscience. 2007 ; 149 (2). 286-302.
25. Chiu CC, Su KP, Cheng TC, et al. The effects of omega-3 fatty acids monotherapy in Alzheimers disease and mild cognitive impairment: a preliminary randomised double-blind placebo-controlled study. Prog Neuropsychopharmacol Biol Psychiatry. 2008 ; 32 (6). 1538-1544.
26. Freund-Levi Y., Eriksdotter-Jönhagen M., Cederholm T., et al. Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial. Arch Neurol. 2006 ; 63 (10). 1402-1428.
27. Kröger E., Verreault R., Carmichael PH, et al. Omega-3 fatty acids and risk of dementia: the Canadian Study of Health and Aging. Am J Clin Nutr. 2009 ; 90 (1). 184-192.
28. Devore EE, Grodstein F., van Rooij FJ, et al. Dietary intake of fish and omega-3 fatty acids in relation to long-term dementia risk. Am J Clin Nutr. 2009 ; 90 (1). 170-176.
29. Samieri C., Féart C., Letenneur L., et al. Low plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia risk. Am J Clin Nutr. 2008 ; 88 (3). 714-721.
30. Calon F., Cole G. Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies. Prostaglandins Leukot Essent Fatty Acids. 2007 ; 77 (5-6). 287-293.
31. Mitchell DC, Gawrisch K., Litman BJ, Salem N Jr.. Why is docosahexaenoic acid essential for nervous system function ? Biochem Soc Trans. 1998 ; 26 (3). 365-370.
32. Kim HY, Akbar M., Kim YS Phosphatidylserine-dependent neuroprotective signaling promoted by docosahexaenoic acid. Prostaglandins Leukot Essent Fatty Acids. 2010 ; 82 (4-6). 165-172.
33. Prasad MR, Lovell MA, Yatin M., Dhillon H., Markesbery WR Regional membrane phospholipid alterations in Alzheimers disease. Neurochem Res. 1998 ; 23 (1). 81-88.
34. Soderberg M., Edlund C., Kristensson K., Dallner G. Fatty acid composition of brain phospholipids in aging and in Alzheimers disease. Lipids. 1991 ; 26 (6). 421-425.
35. Yurko-Mauro K. Cognitive and cardiovascular benefits of docosahexaenoic acid in aging and cognitive decline. Curr Alzheimer Res. 2010 ; 7 (3). 190-196.
36. Fotuhi M., Mohassel P., Yaffe K. Fish consumption, long-chain omega-3 fatty acids and risk of cognitive decline or Alzheimer disease: a complex association. Nat Clin Pract Neurol. 2009 ; 5 (3). 140-152.
37. Calon F., Lim GP, Yang F., et al. Docosahexaenoic acid protects from dendritic pathology in an Alzheimers disease mouse model. Neuron. 2004 ; 43 (5). 633-645.
38. Lim GP, Calon F., Morihara T., et al. A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model. J Neurosci. 2005 ; 25 (12). 3032-3040.
39. Mucke L., Masliah E., Yu GQ, et al. High-level neuronal expression of Abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J Neurosci. 2000 ; 20 (11). 4050-4058.
40. Florent S., Malaplate-Armand C., Youssef I., et al. Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-beta oligomers. J Neurochem. 2006 ; 96 (2). 385-395.
41. Liu L., Komatsu H., Murray IV, Axelsen PH Promotion of amyloid beta protein misfolding and fibrillogenesis by a lipid oxidation product. J Mol Biol. 2008 ; 377 (4). 1236-1250.