Efficacy, heat stability and safety of intranasally administered Bacillus subtilis spore or vegetative cell vaccines expressing tetanus toxin fragment C

Vaccine

Volumn 28, Issue 41, 2010, Pages 6658-6665

  Lee, Sangun ^a   Belitsky, Boris R ^b   Brown, David W ^a   Brinker, James P ^a   Kerstein, Kathryn O ^b   Herrmann, John E ^a   Keusch, Gerald T ^c   Sonenshein, Abraham L ^b   Tzipori, Saul ^a  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

B. subtilis; Tetanus; Vaccine

Indexed keywords

DIPHTHERIA PERTUSSIS TETANUS VACCINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; TETANUS TOXOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BACILLUS SUBTILIS; BACTERIAL SPORE; BRAIN; CONTROLLED STUDY; DRUG STABILITY; FEMALE; LYOPHILISATE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY SYSTEM; SCID MOUSE; THERMOSTABILITY; VACCINATION; VACCINE PRODUCTION;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, BACTERIAL; BACILLUS SUBTILIS; BASE SEQUENCE; FEMALE; FREEZE DRYING; MICE; MICE, INBRED BALB C; MICE, SCID; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; TETANUS; TETANUS TOXIN; TETANUS TOXOID;

EID: 77956480262     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.08.016     Document Type: Article

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