Charged amino acids in the AMPV fusion protein have more influence on induced protection than deletion of the SH or G genes

Vaccine

Volumn 28, Issue 41, 2010, Pages 6800-6807

  Naylor, Clive J ^a   Lupini, Caterina ^b   Brown, Paul A ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Fusion protein; Metapneumovirus; Protection; Virus replication

Indexed keywords

HYBRID PROTEIN; MEMBRANE PROTEIN; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENICITY; ARTICLE; AVIAN PNEUMOVIRUS; CONTROLLED STUDY; DNA MODIFICATION; G GENE; GENE DELETION; HELPER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SH GENE; TURKEY (BIRD); VIRUS GENE; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS VIRULENCE;

AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; GENE DELETION; METAPNEUMOVIRUS; ORGAN CULTURE TECHNIQUES; PARAMYXOVIRIDAE INFECTIONS; POULTRY DISEASES; RECOMBINANT FUSION PROTEINS; TURKEYS; VERO CELLS; VIRAL PROTEINS; VIRULENCE;

EID: 77956471091     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.07.015     Document Type: Article

References (49)

1. Buys S.B., Du Prees J.H. A preliminary report on the isolation of a virus causing sinusitis in turkeys in South Africa and attempts to attenuate the virus. Turkeys 1980, 28:36.
2. Stuart J.C. Rhinotracheitis: turkey rhinotracheitis (TRT) in Great Britain 1989, Butterworth, London.
3. Cook J.K.A., Chester J., Orthel F., Woods M.A., Orbell S.J., Baxendale W., et al. Avian pneumovirus infection of laying hens: experimental studies. Avian Pathol 2000, 29:545-556.
4. Easton A.J., Domachowske J.B., Rosenberg H.F. Animal pneumoviruses: molecular genetics and pathogenesis. Clin Microbiol Rev 2004, 17(April (2)):390-412.
5. Pringle C.R. Virus taxonomy-San Diego 1998. Arch Virol 1998, 143(7):1449-1459.
6. van den Hoogen B.G., de Jong J.C., Groen J., Kuiken T., de Groot R., Fouchier R.A., et al. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med 2001, 7(June (6)):719-724.
7. Bayon-Auboyer M.H., Arnauld C., Toquin D., Eterradossi N. Nucleotide sequences of the F, L and G protein genes of two non-A/non-B avian pneumoviruses (APV) reveal a novel APV subgroup. J Gen Virol 2000, 81(November (Pt. 11)):2723-2733.
8. Juhasz K., Easton A.J. Extensive sequence variation in the attachment (G) protein gene of avian pneumovirus: evidence for two distinct subgroups. J Gen Virol 1994, 75(Pt 11):2873-2880.
9. Seal B.S. Avian pneumovirus and emergence of a new type in the United States of America. Anim Health Res Rev 2000, (1):67-72.
10. Van de Zande S., Nauwynck H., Naylor C., Pensaert M. Duration of cross-protection between subtypes A and B avian pneumovirus in turkeys. Vet Rec 2000, 147(July (5)):132-134.
11. Buys S.B., du Preez J.H., Els H.J. The isolation and attenuation of a virus causing rhinotracheitis in turkeys in South Africa. Onderstepoort J Vet Res 1989, 56(June (2)):87-98.
12. Cook J.K., Huggins M.B., Woods M.A., Orbell S.J., Mockett A.P. Protection provided by a commercially available vaccine against different strains of turkey rhinotracheitis virus. Vet Rec 1995, April (136)(15):392-393.
13. Cook J.K.A., Ellis M.M. Attenuation of turkey rhinotracheitis virus by alternative passage in embryonated chicken eggs and tracheal organ cultures. Avian Pathol 1990, 19:181-185.
14. Cook J.K.A., Ellis M.M., Dolby C.A., Holmes H.C., Finney P.M., Huggins M.B. A live attenuated turkey rhinotracheitis virus vaccine. I. Stability of the attenuated strain. Avian Pathol 1989, 18:511-522.
15. Cook J.K.A., Holmes H.C., Finney P.M., Dolby C.A., Ellis M.M., Huggins M.B. A live attenuated turkey rhinotracheitis virus-vaccine. 2. The use of the attenuated strain as an experimental vaccine. Avian Pathol 1989, 18(3):523-534.
16. Cook J.K.A., Orthel F., Orbell S., Woods M.A., Huggins M.B. An experimental turkey rhinotracheitis (TRT) infection in breeding turkeys and the prevention of its clinical effects using live-attenuated and inactivated TRT vaccines. Avian Pathol 1996, 25(June (2)):231-243.
17. Williams R.A., Savage C.E., Jones R.C. Development of a live attenuated vaccine against turkey rhinotracheitis. Avian Pathol 1991, 20(1):45-55.
18. Patnayak D.P., Goyal S.M. Duration of immunity engendered by a single dose of a cold-adapted strain of avian pneumovirus. Can J Vet Res 2006, 70(January (1)):65-67.
19. Catelli E., Cecchinato M., Savage C.E., Jones R.C., Naylor C.J. Demonstration of loss of attenuation and extended field persistence of a live avian metapneumovirus vaccine. Vaccine 2006, (July).
20. Naylor C.J., Ling R., Edworthy N., Savage C.E., Easton A.J. Avian metapneumovirus SH gene end and G protein mutations influence the level of protection of live-vaccine candidates. J Gen Virol 2007, 88(June (Pt. 6)):1767-1775.
21. Naylor C.J., Brown P.A., Edworthy N., Ling R., Jones R.C., Savage C.E., et al. Development of a reverse-genetics system for Avian pneumovirus demonstrates that the small hydrophobic (SH) and attachment (G) genes are not essential for virus viability. J Gen Virol 2004, 85(November (Pt. 11)):3219-3227.
22. Ling R., Sinkovic S., Toquin D., Guionie O., Eterradossi N., Easton A.J. Deletion of the SH gene from avian metapneumovirus has a greater impact on virus production and immunogenicity in turkeys than deletion of the G gene or M2-2 open reading frame. J Gen Virol 2008, 89(Pt. 2 (February)):525-533.
23. Bukreyev A., Whitehead S.S., Murphy B.R., Collins P.L. Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse. J Virol 1997, 71(December (12)):8973-8982.
24. Jin H., Cheng X., Zhou H.Z., Li S., Seddiqui A. Respiratory syncytial virus that lacks open reading frame 2 of the M2 gene (M2-2) has altered growth characteristics and is attenuated in rodents. J Virol 2000, 74(January (1)):74-82.
25. Whitehead S.S., Bukreyev A., Teng M.N., Firestone C.Y., St.Claire M., Elkins W.R., et al. Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees. J Virol 1999, 73(April (4)):3438-3442.
26. Qingzhong Y., Barrett T., Brown T.D., Cook J.K., Green P., Skinner M.A., et al. Protection against turkey rhinotracheitis pneumovirus (TRTV) induced by a fowlpox virus recombinant expressing the TRTV fusion glycoprotein (F). Vaccine 1994, 12(May (6)):569-573.
27. Kapczynski D.R., Sellers H.S. Immunization of turkeys with a DNA vaccine expressing either the F or N gene of avian metapneumovirus. Avian Dis 2003, 47(October-December (4)):1376-1383.
28. Brown P.A., Bonci M., Ricchizzi E., Jones R.C., Naylor C.J. Identification of two regions within the subtype A avian metapneumovirus fusion protein (amino acids 211-310 and 336-479) recognized by neutralizing antibodies. Virus Res 2009, (August).
29. Naylor C.J., Jones R.C. Demonstration of a virulent subpopulation in a prototype live attenuated turkey rhinotracheitis vaccine. Vaccine 1994, 12(13):1225-1230.
30. Naylor C.J., Worthington K.J., Jones R.C. Failure of maternal antibodies to protect young turkey poults against challenge with turkey rhinotracheitis virus. Avian Dis 1997, 41(October-December (4)):968-971.
31. Pattison M.M.P., Bradbury J., Alexander D. Poultry diseases 2008, Saunders Elsevier. 6th ed.
32. Worthington K.J., Sargent B.A., Davelaar F.G., Jones R.C. Immunity to avian pneumovirus infection in turkeys following in ovo vaccination with an attenuated vaccine. Vaccine 2003, 21(March (13-14)):1355-1362.
33. Naylor C.J. A method of exchanging RNA sequences between protective and unprotective candidate APV vaccines reveals some regions important in stimulating protection. V International Symposium on Avian Corona and Pneumoviruses and Complicating Pathogens 2006, 98-102. VVB Laufersweiler Verlag/University of Giessen Rauischholzhausen, Germany. U. Heffels-Redman, E.F. Kaleta (Eds.).
34. Cecchinato M, Catelli E, Lupini C, Ricchizzi E, Clubbe J, Battilani M, et al. Avian metapneumovirus (AMPV) attachment protein involvement in probable virus evolution concurrent with mass live vaccine introduction. Vet Microbiol, Apr 20, 2010. [Epub ahead of print].
35. Cole C., Barber J.D., Barton GJ The Jpred 3 secondary structure prediction server. Nucleic Acids Res 2008, 36(July (web server issue)):W197-W201.
36. Romero, Obradovic, Dunker K. Sequence data analysis for long disordered regions prediction in the Calcineurin family. Genome Inform Ser Workshop Genome Inform 1997, 8:110-124.
37. Emini E.A., Hughes J.V., Perlow D.S., Boger J. Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide. J Virol 1985, 55(September (3)):836-839.
38. Margalit H., Spouge J.L., Cornette J.L., Cease K.B., Delisi C., Berzofsky J.A. Prediction of immunodominant helper T cell antigenic sites from the primary sequence. J Immunol 1987, 138(April (7)):2213-2229.
39. Julenius K., Molgaard A., Gupta R., Brunak S. Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites. Glycobiology 2005, 15(February (2)):153-164.
40. Cavanagh D., Mawditt K., Britton P., Naylor C.J. Longitudinal field studies of infectious bronchitis virus and avian pneumovirus in broilers using type-specific polymerase chain reactions. Avian Pathol 1999, 28:593-605.
41. Naylor CJ. Studies on avian pneumoviruses including development of a vaccine. PhD thesis; 1993. p. 125-30.
42. de Graaf M., Schrauwen E.J., Herfst S., van Amerongen G., Osterhaus A.D., Fouchier R.A. Fusion protein is the main determinant of metapneumovirus host tropism. J Gen Virol 2009, 90(June (Pt. 6)):1408-1416.
43. Catelli E., Lupini C., Cecchinato M., Ricchizzi E., Brown P., Naylor C.J. Field avian metapneumovirus evolution avoiding vaccine induced immunity. Vaccine 2010, 28(January (4)):916-921.
44. Williams R.A., Savage C.E., Worthington K.J., Jones R.C. Further studies on the development of a live attenuated vaccine against turkey rhinotracheitis. Avian Pathol 1991, 20:585-596.
45. Banet-Noach C., Simanov L., Laham-Karam N., Perk S., Bacharach E. Longitudinal survey of avian metapneumoviruses in poultry in Israel: infiltration of field strains into vaccinated flocks. Avian Dis 2009, 53(June (2)):184-189.
46. Cook J.K., Huggins M.B., Orbell S.J., Senne D.A. Preliminary antigenic characterization of an avian pneumovirus isolated from commercial turkeys in Colorado, USA. Avian Pathol 1999, 28(6):607-617.
47. Rubbenstroth D., Rautenschlein S. Investigations on the protective role of passively transferred antibodies against avian metapneumovirus infection in turkeys. Avian Pathol 2009, 38(December (6)):427-436.
48. Jones R.C., Naylor C.J., al-Afaleq A., Worthington K.J., Jones R. Effect of cyclophosphamide immunosuppression on the immunity of turkeys to viral rhinotracheitis. Res Vet Sci 1992, 53(July (1)):38-41.
49. Rautenschlein S., Rubbenstroth D. The role of humoral and cell-mediated immunity in the control of avian metapneumovirus infection in turkeys. International symposium on avian corona and pneumoviruses and complicating pathogens 2009, University of Giessen Rauischholzhausen, Germany. U. Heffels-Redman, E.F. Kaleta (Eds.).