Screening the three LHON primary mutations in the general Chinese population by using an optimized multiplex allele-specific PCR

Clinica Chimica Acta

Volumn 411, Issue 21-22, 2010, Pages 1671-1674

  Bi, Rui ^a,b   Zhang, A Mei ^a,b   Yu, Dandan ^a   Chen, Diana ^a   Yao, Yong Gang ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

General population; LHON; MAS PCR; MtDNA; Primary mutation

Indexed keywords

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; CHINESE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; GENETIC COUNSELING; GENETIC SCREENING; HETEROPLASMY; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SENSITIVITY ANALYSIS;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; DNA, MITOCHONDRIAL; FEMALE; HETEROZYGOTE; HETEROZYGOTE DETECTION; HUMANS; MALE; MASS SCREENING; MUTATION; OPTIC ATROPHY, HEREDITARY, LEBER; POINT MUTATION; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 77956454162     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2010.06.026     Document Type: Article

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