Low treatment adherence with antipsychotics is associated with relapse in psychotic disorders within six months after discharge

Pharmacopsychiatry

Volumn 43, Issue 6, 2010, Pages 221-224

  Laan, W ^a   Van Der Does, Y ^a   Sezgi, B ^b   Smeets, H M ^a   Stolker, J J ^b,c,d   De Wit, N J ^a   Heerdink, E R ^b,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c Altrecht Mental Health Institute   (Netherlands)

^d Currently Employed by Arkin   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROLEPTIC AGENT;

ADULT; ARTICLE; FEMALE; HAZARD RATIO; HOSPITAL DISCHARGE; HOSPITAL PATIENT; HOSPITAL READMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT COMPLIANCE; PRIORITY JOURNAL; PSYCHOSIS; RELAPSE; SCHIZOPHRENIA;

ADULT; ANTIPSYCHOTIC AGENTS; COHORT STUDIES; COMORBIDITY; FEMALE; HOSPITALIZATION; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; PATIENT DISCHARGE; PSYCHOTIC DISORDERS; RECURRENCE; SCHIZOPHRENIA; YOUNG ADULT;

EID: 77956444323     PISSN: 01763679     EISSN: 14390795     Source Type: Journal    
DOI: 10.1055/s-0030-1254090     Document Type: Article

References (14)

1. dosReis S, Johnson E, Steinwachs D, et al. Antipsychotic treatment patterns and hospitalizations among adults with schizophrenia. Schizophr Res 2008 101 304-311
2. Freedman R. Schizophrenia. N Engl J Med 2003 349 1738-1749
3. Law MR, Soumerai SB, Ross-Degnan D, etal. A longitudinal study of medication nonadherence and hospitalization risk in schizophrenia. J Clin Psychiatry 2008 69 47-53
4. Morken G, Widen J, Grawe R. Non-adherence to antipsychotic medication, relapse and rehospitalisation in recent-onset schizophrenia. BMC Psychiatry 2008 8 32
5. Muller N. Mechanisms of relapse prevention in schizophrenia. Pharmacopsychiatry 2004 37 141-147
6. Ohmori T, Ito K, Abekawa T, etal. Psychotic relapse and maintenance therapy in paranoid schizophrenia: a 15 year follow up. Eur Arch Psychiatry Clin Neurosci 1999 249 73-78
7. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med 2005 353 487-497
8. Rajkumar S, Thara R. Factors affecting relapse in schizophrenia. Schizophrenia Res 1989 2 403-409
9. Rosen K, Garety P. predicting recovery from schizophrenia: a retrospective comparison of characteristics at onset of people with single and multiple episodes. Schizophr Bull 2005 31 735-750
10. Simpson SH, Eurich DT, Majumdar SR, etal. A meta-analysis of the association between adherence to drug therapy and mortality. BMJ 2006 333 15
11. Steiner JF, Prochazka AV. The assessment of refill compliance using pharmacy records: Methods, validity, and applications. J Clin Epidemiol 1997 50 105-116
12. Weiden PJ, Kozma C, Grogg A, etal. Partial compliance and risk of rehospitalization among california medicaid patients with schizophrenia. Psychiatr Serv 2004 55 886-891
13. WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index 2008. Internet 2008 July 29; available from: URL: http://www.whocc.no/atcddd/
14. Wiersma D, Nienhuis FJ, Slooff CJ, etal. Natural course of schizophrenic disorders: a 15-year follow-up of a Dutch incidence cohort. Schizophr Bull 1998 24 75-85