Partial and ineffective activation of Vγ9Vδ2 T cells by Mycobacterium tuberculosis-infected dendritic cells

Journal of Immunology

Volumn 185, Issue 3, 2010, Pages 1770-1776

  Meraviglia, Serena ^a   Caccamo, Nadia ^a   Salerno, Alfredo ^a   Sireci, Guido ^a   Dieli, Francesco ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; HLA DR ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; T CELL RECEPTOR VDELTA2, HUMAN; T CELL RECEPTOR VGAMMA9, HUMAN; T-CELL RECEPTOR VDELTA2, HUMAN; T-CELL RECEPTOR VGAMMA9, HUMAN;

ARTICLE; CELL CONTACT; CELL DIFFERENTIATION; CELL MATURATION; CELL POPULATION; CELL VIABILITY; CONTROLLED STUDY; CYTOLYSIS; DENDRITIC CELL; EFFECTOR CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INNATE IMMUNITY; LYMPHOCYTE ACTIVATION; MEMORY T LYMPHOCYTE; MYCOBACTERIUM TUBERCULOSIS; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; TUBERCULOSIS; UPREGULATION; V GAMMA 9 V DELTA 2 T LYMPHOCYTE; ADULT; BIOSYNTHESIS; CELL CULTURE; COCULTURE; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY TEST; FEMALE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOPHENOTYPING; MALE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; T LYMPHOCYTE SUBPOPULATION; TUMOR CELL LINE;

ADULT; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOTOXICITY TESTS, IMMUNOLOGIC; DENDRITIC CELLS; FEMALE; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 77956406610     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000966     Document Type: Article

References (39)

1. Münz, C., R. M. Steinman, and S. Fujii. 2005. Dendritic cell maturation by innate lymphocytes: coordinated stimulation of innate and adaptive immunity. J. Exp. Med. 202: 203-207.
2. Förtsch, D., M. Röllinghoff, and S. Stenger. 2000. IL-10 converts human dendritic cells into macrophage-like cells with increased antibacterial activity against virulent Mycobacterium tuberculosis. J. Immunol. 165: 978-987. (Pubitemid 30484767)
3. Tascon, R. E., C. S. Soares, S. Ragno, E. Stavropoulos, E. M. Hirst, and M. J. Colston. 2000. Mycobacterium tuberculosis-activated dendritic cells induce protective immunity in mice. Immunology 99: 473-480.
4. Henderson, R. A., S. C. Watkins, and J. L. Flynn. 1997. Activation of human dendritic cells following infection with Mycobacterium tuberculosis. J. Immunol. 159: 635-643.
5. Demangel, C., and W. J. Britton. 2000. Interaction of dendritic cells with mycobacteria: where the action starts. Immunol. Cell Biol. 78: 318-324.
6. Mohagheghpour, N., A. van Vollenhoven, J. Goodman, and L. E. Bermudez. 2000. Interaction of Mycobacterium avium with human monocyte-derived dendritic cells. Infect. Immun. 68: 5824-5829.
7. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
8. Sertl, K., T. Takemura, E. Tschachler, V. J. Ferrans, M. A. Kaliner, and E. M. Shevach. 1986. Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura. J. Exp. Med. 163: 436-451.
9. Holt, P. G., and M. A. Schon-Hegrad. 1987. Localization of T cells, macrophages, and dendritic cells in rat respiratory tract tissue: implications for immune functions studies. Immunology 62: 349-356.
10. van Haarst, J. M., H. C. Hoogsteden, H. J. de Wit, G. T. Verhoeven, C. E. Havenith, and H. A. Drexhage. 1994. Dendritic cells and their precursors isolated from human bronchoalveolar lavage: immunocytologic and functional properties. Am. J. Respir. Cell Mol. Biol. 11: 344-350.
11. Salerno, A., and F. Dieli. 1998. Role of g d T lymphocytes in immune response in humans and mice. Crit. Rev. Immunol. 18: 327-357.
12. Dieli, F., F. Poccia, M. Lipp, G. Sireci, N. Caccamo, C. Di Sano, and A. Salerno. 2003. Differentiation of effector/memory Vdelta2 T cells and migratory routes in lymph nodes or inflammatory sites. J. Exp. Med. 198: 391-397.
13. Dieli, F., J. Ivanyi, P. Marsh, A. Williams, I. Naylor, G. Sireci, N. Caccamo, C. Di Sano, and A. Salerno. 2003. Characterization of lung γ δ T cells following intranasal infection with Mycobacterium bovis bacillus Calmette-Guérin. J. Immunol. 170: 463-469. (Pubitemid 36026172)
14. Dieli, F., N. Caccamo, S. Meraviglia, J. Ivanyi, G. Sireci, C. T. Bonanno, V. Ferlazzo, C. La Mendola, and A. Salerno. 2004. Reciprocal stimulation of gammadelta T cells and dendritic cells during the anti-mycobacterial immune response. Eur. J. Immunol. 34: 3227-3235.
15. Caccamo, N., G. Sireci, S. Meraviglia, F. Dieli, J. Ivanyi, and A. Salerno. 2006. gammadelta T cells condition dendritic cells in vivo for priming pulmonary CD8 T cell responses against Mycobacterium tuberculosis. Eur. J. Immunol. 36: 2681-2690.
16. Conti, L., R. Casetti, M. Cardone, B. Varano, A. Martino, F. Belardelli, F. Poccia, and S. Gessani. 2005. Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gammadelta T cells: role of CD86 and inflammatory cytokines. J. Immunol. 174: 252-260. (Pubitemid 40007411)
17. Martino, A., R. Casetti, A. Sacchi, and F. Poccia. 2007. Central memory Vgamma9Vdelta2 T lymphocytes primed and expanded by bacillus Calmette-Guérin-infected dendritic cells kill mycobacterial-infected monocytes. J. Immunol. 179: 3057-3064.
18. Diagnostic standards and classification of tuberculosis in adults and children. This official statement of the American Thoracic Society and the Centers for Disease Control and Prevention was adopted by the ATS Board of Directors, July 1999. This statement was endorsed by the Council of the Infectious Disease Society of America, September 1999. 2000. Am. J. Respir. Crit. Care Med. 161: 1376-1395.
19. Dieli, F., M. Troye-Blomberg, J. Ivanyi, J. J. Fournié, M. Bonneville, M. A. Peyrat, G. Sireci, and A. Salerno. 2000. Vgamma9/Vdelta2 T lymphocytes reduce the viability of intracellular Mycobacterium tuberculosis. Eur. J. Immunol. 30: 1512-1519.
20. Dieli, F., M. Troye-Blomberg, J. Ivanyi, J. J. Fournié, A. M. Krensky, M. Bonneville, M. A. Peyrat, N. Caccamo, G. Sireci, and A. Salerno. 2001. Granulysin-dependent killing of intracellular and extracellular Mycobacterium tuberculosis by Vgamma9/Vdelta2 T lymphocytes. J. Infect. Dis. 184: 1082-1085.
21. Dieli, F., D. Vermijlen, F. Fulfaro, N. Caccamo, S. Meraviglia, G. Cicero, A. Roberts, S. Buccheri, M. D'Asaro, N. Gebbia, et al. 2007. Targeting human γδ T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer. Cancer Res. 67: 7450-7457. (Pubitemid 47206575)
22. De Libero, G., A. Collmann, and L. Mori. 2009. The cellular and biochemical rules of lipid antigen presentation. Eur. J. Immunol. 39: 2648-2656.
23. Caccamo, N., S. Meraviglia, V. Ferlazzo, D. Angelini, G. Borsellino, F. Poccia, L. Battistini, F. Dieli, and A. Salerno. 2005. Differential requirements for antigen or homeostatic cytokines for proliferation and differentiation of human Vgamma9Vdelta2 naive, memory and effector T cell subsets. Eur. J. Immunol. 35: 1764-1772.
24. Soilleux, E. J., L. S. Morris, G. Leslie, J. Chehimi, Q. Luo, E. Levroney, J. Trowsdale, L. J. Montaner, R. W. Doms, D. Weissman, et al. 2002. Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro. J. Leukoc. Biol. 71: 445-457.
25. Marino, S., S. Pawar, C. L. Fuller, T. A. Reinhart, J. L. Flynn, and D. E. Kirschner. 2004. Dendritic cell trafficking and antigen presentation in the human immune response to Mycobacterium tuberculosis. J. Immunol. 173: 494-506.
26. Yoshie, O. 2000. Role of chemokines in trafficking of lymphocytes and dendritic cells. Int. J. Hematol. 72: 399-407.
27. Schaible, U. E., H. L. Collins, and S. H. Kaufmann. 1999. Confrontation between intracellular bacteria and the immune system. Adv. Immunol. 71: 267-377.
28. Stenger, S., and R. L. Modlin. 1999. T cell mediated immunity to Mycobacterium tuberculosis. Curr. Opin. Microbiol. 2: 89-93.
29. Dulphy, N., J. L. Herrmann, J. Nigou, D. Réa, N. Boissel, G. Puzo, D. Charron, P. H. Lagrange, and A. Toubert. 2007. Intermediate maturation of Mycobacterium tuberculosis LAM-activated human dendritic cells. Cell. Microbiol. 9: 1412-1425.
30. Hanekom, W. A., M. Mendillo, C. Manca, P. A. Haslett, M. R. Siddiqui, C. Barry, III, and G. Kaplan. 2003. Mycobacterium tuberculosis inhibits maturation of human monocyte-derived dendritic cells in vitro. J. Infect. Dis. 188: 257-266.
31. Motta, A., C. Schmitz, L. Rodrigues, F. Ribeiro, C. Teixeira, T. Detanico, C. Bonan, H. Zwickey, and C. Bonorino. 2007. Mycobacterium tuberculosis heat-shock protein 70 impairs maturation of dendritic cells from bone marrow precursors, induces interleukin-10 production and inhibits T-cell proliferation in vitro. Immunology 121: 462-472. (Pubitemid 47030084)
32. Wolf, A. J., B. Linas, G. J. Trevejo-Nuñez, E. Kincaid, T. Tamura, K. Takatsu, and J. D. Ernst. 2007. Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. J. Immunol. 179: 2509-2519.
33. Janis, E. M., S. H. E. Kaufmann, R. H. Schwartz, and D. M. Pardoll. 1989. Activation of g d T cells in the primary immune response to Mycobacterium tuberculosis. Science 244: 713-716.
34. Boom, W. H. 1999. Gammadelta T cells and Mycobacterium tuberculosis. Microbes Infect. 1: 187-195.
35. Lee, J., K. Choi, M. R. Olin, S. N. Cho, and T. W. Molitor. 2004. Gammadelta T cells in immunity induced by Mycobacterium bovis bacillus Calmette-Guérin vaccination. Infect. Immun. 72: 1504-1511.
36. Ismaili, J., V. Olislagers, R. Poupot, J. J. Fournié, and M. Goldman. 2002. Human γ δ T cells induce dendritic cell maturation. Clin. Immunol. 103: 296-302.
37. Leslie, D. S., M. S. Vincent, F. M. Spada, H. Das, M. Sugita, C. T. Morita, and M. B. Brenner. 2002. CD1-mediated gamma/delta T cell maturation of dendritic cells. J. Exp. Med. 196: 1575-1584.
38. Gao, Y., W. Yang, M. Pan, E. Scully, M. Girardi, L. H. Augenlicht, J. Craft, and Z. Yin. 2003. Gamma delta T cells provide an early source of interferon gamma in tumor immunity. J. Exp. Med. 198: 433-442.
39. Dieli, F., G. Sireci, N. Caccamo, C. Di Sano, L. Titone, A. Romano, P. Di Carlo, A. Barera, A. Accardo-Palumbo, A. M. Krensky, and A. Salerno. 2002. Selective depression of interferon-γ and granulysin production with increase of proliferative response by Vgamma9/Vdelta2 T cells in children with tuberculosis. J. Infect. Dis. 186: 1835-1839.