Thermodynamic study of the solubility of ibuprofen in acetone and dichloromethane

Brazilian Journal of Pharmaceutical Sciences

Volumn 46, Issue 2, 2010, Pages 227-235

  Aragón, Diana Marcela ^a   Rosas, Jaiver Eduardo ^a   Martínez, Fleming ^a  

^a UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

Ibuprofen; Organic solvents; Solubility; Solution thermodynamics; Transfer

Indexed keywords

ACETONE; DICHLOROMETHANE; IBUPROFEN; CYCLOHEXANE; HYDROGEN; SOLVENT;

ARTICLE; DRUG ABSORPTION; DRUG SOLUBILITY; DRUG STRUCTURE; SOLVATION; TEMPERATURE MEASUREMENT; THERMODYNAMICS; CHEMICAL INTERACTION; ENTHALPY; ENTROPY; HYDROGEN BOND; SOLUTE; TEMPERATURE;

EID: 77956395897     PISSN: 19848250     EISSN: 21759790     Source Type: Journal    
DOI: 10.1590/S1984-82502010000200009     Document Type: Article

References (20)

1. BARTON, A. Handbook of solubility parameters and other cohesion parameters. 2.ed. New York: CRC Press, 1991. p.157-193.
2. BEVINGTON, P. R. Data reduction and error analysis for the physical sciences. New York: McGraw-Hill Book, Co., 1969. p.56-65.
3. BUDAVARI, S.; O'NEIL, M. J.; SMITH, A.; HECKELMAN, P. E.; OBENCHAIN JR, J. R.; GALLIPEAU, J. A. R.; D'ARECEA, M. A. The Merck Index: an encyclopedia of chemicals, drugs, and biologicals. 13.ed. Whitehouse Station: Merck & Co., Inc., 2001. p.876.
4. BUSTAMANTE, P.; ROMERO, S.; PEÑA, A.; REILLO, A. Enthalpy-entropy compensation for the solubility of drugs in solvent mixtures: Paracetamol, acetanilide, and nalidixic acid in dioxane-water. J. Pharm. Sci., v.87, n.12, p.1590-1596, 1998.
5. FEDORS, R. F. A method for estimating both the solubility parameters and molar volumes of liquids. Polym. Eng. Sci., New York, v.14, n.2, p.147-154, 1974.
6. GARZÓN, L. C.; MARTÍNEZ, F. Temperature-solubility dependence for ibuprofen in some organic and aqueous solvents. J. Solution Chem., v.33, n.11, p.1379-1395, 2004.
7. HANSEN, J. M. The three dimensional solubility parameter and solvent diffusion coefficient. Importance in surface coating formulation. Copenhagen: Danish Technical Press, 1967. 106 p. [Ph.D. Thesis. College of Advanced Technology].
8. HILDEBRAND, J. H.; PRAUSNITZ, J. M.; SCOTT, R. L. Regular and related solutions. New York: Van Nostrand Reinhold, 1970. 228 p.
9. KRISTL, A.; VESNAVER, G. Thermodynamic investigation of the effect of octanol-water mutual miscibility on the partitioning and solubility of some guanine derivatives. J. Chem. Soc. Faraday Trans., v.91, n.6, p.995-998, 1995.
10. KRUG, R. R.; HUNTER, W. G.; GRIEGER, R. A. Enthalpy-entropy compensation. 2. Separation of the chemical from the statistical effects. J. Phys. Chem., Washington, v.80, n.21, p.2341-2351, 1976.
11. MANRIQUE, J.; MARTÍNEZ, F. Solubility of ibuprofen in some ethanol + water cosolvent mixtures at several temperatures. Lat. Am. J. Pharm., v.26, n.3, p.344-354, 2007.
12. MANRIQUE, Y. J.; PACHECO, D. P.; MARTÍNEZ, F. Thermodynamics of mixing and solvation of ibuprofen and naproxen in propylene glycol + water cosolvent mixtures. J. Solution Chem., New York, v.37, n.2, p.165-181, 2008.
13. MARTIN, A.; BUSTAMANTE, P. El parámetro de solubilidad en las ciencias farmacéuticas. Anal. Real Acad. Farm., Madrid, v.55, n.2, p.175-202, 1989.
14. MARTIN, A.; BUSTAMANTE, P.; CHUN, A. H. C. Physical pharmacy: physical chemical principles in the pharmaceutical sciences. 4.ed. Philadelphia: Lea & Febiger, 1993. p.223-227.
15. PERLOVICH, G. L.; KURKOV, S. V.; HANSEN, L. K.; BAUER-BRANDL, A. Thermodynamics of sublimation, crystal lattice energies, and crystal structures of racemates and enantiomers: (+)- and (+/-)-ibuprofen. J. Pharm. Sci., Washington, v.93, n.3, p.654-666, 2004.
16. ROBERTS II, L. J.; MORROW, J. D. Analgesic-antipyretic and anti-inflammatory agents and drugs employed in the treatment of gout. In: HARDMAN, J. G.; LIMBIRD, L. E.; GILMAN, A. G. (Eds.). Goodman & Gilman's. The Pharmacological basis of therapeutics. 10.ed. New York: McGraw-Hill, 2001. p.703-705.
17. ROSENSTEIN-STER, E. Diccionario de especialidades farmacéuticas. 32.ed. Bogotá: Thompson P. L. M., S. A., 2004. p.553-554.
18. TEWES, F.; BOURY, F.; BENOIT, J. P. Biodegradable microspheres: Advances in production technology. In: BENITA, S. (Ed.). Microencapsulation: Methods and industrial applications. 2.ed. New York: Taylor & Francis Group, LLC, 2006. p.1-53.
19. TRIANA, M. T.; REYES, A. C.; JIMENEZ-KAIRUZ, A. F.; MANZO, R. H.; MARTÍNEZ, F. Solution and mixing thermodynamics of propranolol and atenolol in aqueous media. J. Solution Chem., New York, v.38, n.1, p.73-81, 2009.
20. UNITED STATES PHARMACOPEIA. 23.ed. Rockville: United States Pharmacopeial Convention, 1994. p.785-786.