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This is a large series of patients with long-term follow-up treated in Japan with excellent documentation of outcomes, patterns of failure, and dose response. It demonstrates safety of the treatment of central tumors with risk-adapted doses. It also includes a group of medically operable patients who elected SBRT over surgery and have outcomes equivalent to surgical patients at this point
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27
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Outcomes of riskadapted fractionated stereotactic radiotherapy for stage I nonsmall- cell lung cancer
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Along with Guckenberger et al. [26], this is one of several large European series with reported long-term outcomes
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36
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Stereotactic body radiation therapy for inoperable early stage lung cancer
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This is a critical report of the outcomes of stereotactic radiation using the US standard for peripheral lesions (60 Gy in three fractions), demonstrating excellent outcomes and safety in a multi-institutional setting
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Possible misinterpretation of demarcated solid patterns of radiation fibrosis on CT scans as tumor recurrence in patients receiving hypofractionated stereotactic radiotherapy for lung cancer
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A pilot trial of serial 18F-fluorodeoxyglucose positron emission tomography in patients with medically inoperable stage I non-small-cell lung cancer treated with hypofractionated stereotactic body radiotherapy
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Prospectively collected data on serial PET changes following stereotactic treatment
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Henderson MA, Hoopes DJ, Fletcher JW, et al.: A pilot trial of serial 18F-fluorodeoxyglucose positron emission tomography in patients with medically inoperable stage I non-small-cell lung cancer treated with hypofractionated stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys 2010, 76:789-795. Prospectively collected data on serial PET changes following stereotactic treatment.
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43
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Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy
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This is an early report of planning parameters to aide in reduction of chest wall toxicity
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Dunlap NE, Cai J, Biedermann GB, et al.: Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys 2010, 76:796-801. This is an early report of planning parameters to aide in reduction of chest wall toxicity.
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