Biochemical and vascular aspects of pediatric chronic fatigue syndrome

Archives of Pediatrics and Adolescent Medicine

Volumn 164, Issue 9, 2010, Pages 817-823

  Kennedy, Gwen ^a   Khan, Faisel ^a   Hill, Alexander ^a   Underwood, Christine ^a   Belch, Jill J F ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BIOCHEMICAL MARKER; C REACTIVE PROTEIN; FREE RADICAL; ISOPROSTANE DERIVATIVE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTIOXIDANT;

ADOLESCENT; APOPTOSIS; ARTERIAL STIFFNESS; ARTICLE; CHEMICAL ANALYSIS; CHILD; CHILDHOOD DISEASE; CHRONIC FATIGUE SYNDROME; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; LEUKOCYTE; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PULSE WAVE; SCHOOL CHILD; SYMPTOMATOLOGY; ARTERY; BLOOD; BLOOD RHEOLOGY; ELASTICITY; HEMODYNAMICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADOLESCENT; ANTIOXIDANTS; APOPTOSIS; ARTERIES; C-REACTIVE PROTEIN; CHILD; CROSS-SECTIONAL STUDIES; ELASTICITY; FATIGUE SYNDROME, CHRONIC; FEMALE; FREE RADICALS; HEMODYNAMICS; HEMORHEOLOGY; HUMANS; ISOPROSTANES; MALE; OXIDATIVE STRESS;

EID: 77956390426     PISSN: 10724710     EISSN: 15383628     Source Type: Journal    
DOI: 10.1001/archpediatrics.2010.157     Document Type: Article

References (47)

1. Carruthers BM, Jain AK, De Meirleir KL, et al. Myalgic encephalomyelitis/chronic fatigue syndrome: clinical working case definition, diagnostic and treatment protocols. J Chronic Fatigue Syndr. 2003;11(1):7-116.
2. Reeves WC, Wagner D, Nisenbaum R, et al. Chronic fatigue syndrome - a clinically empirical approach to its definition and study. BMC Med. 2005;3:19-28. (Pubitemid 43013364)
3. Jason LA, Richman JA, Rademaker AW, et al. A community-based study of chronic fatigue syndrome. Arch Intern Med. 1999;159(18):2129-2137. (Pubitemid 29483152)
4. Reyes tj;2M, Nisenbaum R, Hoaglin DC, et al. Prevalence and incidence of chronic fatigue syndrome in Wichita, Kansas. Arch Intern Med. 2003;163(13):1530-1536.
5. NICE clinical guideline 53: chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy): diagnosis and management of CFS/ME in adults and children. National Institute for Health and Clinical Excellence Web site. http://guidance .nice.org.uk/CG53. Accessed September 6, 2009.
6. Reynolds KJ, Vernon SD, Bouchery E, Reeves WC. The economic impact of chronic fatigue syndrome. Cost Eff Resour Alloc. 2004;2(1):4. (Pubitemid 39111896)
7. Galpine JF. Benign myalgic encephalomyelitis. Br J Clin Pract. 1958;12(3):186-188, passim.
8. Acheson ED. The clinical syndrome variously called benign myalgic encephalomyelitis, Iceland disease and epidemic neuromyasthenia. Am J Med. 1959;26 (4):569-595.
9. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A; International Chronic Fatigue Syndrome Study Group. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med. 1994;121(12): 953-959.
10. Arav-Boger R, Spirer Z. Chronic fatigue syndrome: pediatric aspects. Isr J Med Sci. 1995;31(5):330-334.
11. Smith M, Carter BD. Chronic fatigue syndrome in adolescence. In: Jason LA, Fennell PA, Taylor RR, eds. Handbook of Chronic Fatigue Syndrome. New York, NY: John Wiley & Sons; 2003:693-712.
12. Jason LA, Bell DS, Row J, et al. A pediatric case definition for myalgic encephalomyelitis and chronic fatigue syndrome. J Chronic Fatigue Syndr. 2006;13 (2/3):1-44. (Pubitemid 46332700)
13. Jordan KM, Jason LA, Mears CJ, et al. Prevalence of pediatric chronic fatigue syndrome in a community-based sample. J Chronic Fatigue Syndr. 2006;13 (2/3):75-77.
14. Department of Health. A report of the CFS/ME working group: report to the Chief Medical Officer of an independent working group. 2002. http://www.dh.gov.uk /en/Publicationsandstatistics/Publications/ PublicationsPolicyAndGuidance /Browsable/DH-4095249. Accessed September 6, 2009.
15. Royal College of Paediatrics and Child Health. Evidence-based guideline for the management of CFS/ME (chronic fatigue syndrome/myalgic encephalopathy) in children and young people. 2004. http://www.rcpch.ac.uk/Research/ce /RCPCH-guidelines. Accessed September 6, 2009.
16. Kennedy G, Spence VA, Underwood C, Belch JJF. Increased neutrophil apoptosis in chronic fatigue syndrome. J Clin Pathol. 2004;57(8):891-893. (Pubitemid 39061444)
17. Kennedy G, Spence VA, McLaren M, Hill A, Underwood C, Belch JJF. Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms. Free Radic Biol Med. 2005;39(5):584-589. (Pubitemid 41112100)
18. Simon H-U. Neutrophil apoptosis pathways and their modifications in inflammation. Immunol Rev. 2003;193(1):101-110.
19. Nwakoby IE, Reddy K, Patel P, et al. Fas-mediated apoptosis of neutrophils in sera of patients with infection. Infect Immun. 2001;69(5):3343-3349. (Pubitemid 32332233)
20. Spence VA, Kennedy G, Belch JJF, Hill A, Khan F. Low-grade inflammation and arterial wave reflection in patients with chronic fatigue syndrome. Clin Sci (Lond). 2008;114(8):561-566. (Pubitemid 351548764)
21. Laurent S, Cockcroft J, Van Bortel L, et al; European Network for Non-invasive Investigation of Large Arteries. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J. 2006;27 (21):2588-2605.
22. Nürnberger J, Keflioglu-Scheiber A, Opazo Saez AM, Wenzel RR, Philipp T, Schäfers RF. Augmentation index is associated with cardiovascular risk. J Hypertens. 2002; 20(12):2407-2414.
23. Covic A, Haydar AA, Bhamra-Ariza P, Gusbeth-Tatomir P, Goldsmith DJ. Aortic pulse wave velocity and arterial wave reflections predict the extent and severity of coronary artery disease in chronic kidney disease patients. J Nephrol. 2005; 18(4):388-396.
24. Chirinos JA, Zambrano JP, Chakko S, et al. Aortic pressure augmentation predicts adverse cardiovascular events in patients with established coronary artery disease. Hypertension. 2005;45(5):980-985.
25. Tanner JM, Taylor GR. Growth. New York, NY: Life Science Library; 1965.
26. Chen CH, Nevo E, Fetics B, et al. Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure. Validation of generalized transfer function. Circulation. 1997;95(7):1827-1836.
27. Weber T, Auer J, O'Rourke MF, et al. Arterial stiffness, wave reflections, and the risk of coronary artery disease. Circulation. 2004;109(2):184-189.
28. Wilkinson IB, MacCallum H, Flint L, Cockcroft JR, Newby DE, Webb DJ. The influence of heart rate on augmentation index and central arterial pressure in humans. J Physiol. 2000;525(pt 1):263-270.
29. Longmire AW, Swift LL, Roberts LJ II, Awad JA, Burk RF, Morrow JD. Effect of oxygen tension on the generation of F2-isoprostanes and malondialdehyde in peroxidizing rat liver microsomes. Biochem Pharmacol. 1994;47(7):1173-1177.
30. Lynch SM, Morrow JD, Roberts LJ II, Frei B. Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro. J Clin Invest. 1994;93(3):998-1004.
31. 2- integrin-mediated rapid adhesion of human polymorphonuclear neutrophils: a link between oxidative stress and ischemia/reperfusion injury. Arterioscler Thromb Vasc Biol. 2001;21(1):55-60.
32. Elliott SJ, Koliwad SK. Oxidant stress and endothelial membrane transport. Free Radic Biol Med. 1995;19(5):649-658.
33. Sametz W, Prasthofer S, Wintersteiger R, Juan H. Vascular effects of isoprostanes after endothelial damage. Prostaglandins Leukot Essent Fatty Acids. 1999; 61(6):369-372.
34. Smirnova IV, Pall ML. Elevated levels of protein carbonyls in sera of chronic fatigue syndrome patients. Mol Cell Biochem. 2003;248(1-2):93-95.
35. Vecchiet J, Cipollone F, Falasca K, et al. Relationship between musculoskeletal symptoms and blood markers of oxidative stress in patients with chronic fatigue syndrome. Neurosci Lett. 2003;335(3):151-154.
36. Robinson M, Gray SR, Watson MS, et al. Plasma IL-6, its soluble receptors and F2-isoprostanes at rest and during exercise in chronic fatigue syndrome. Scand J Med Sci Sports. 2010;20(2):282-290.
37. Lane RJM, Soteriou BA, Zhang H, Archard LC. Enterovirus related metabolic myopathy: a postviral fatigue syndrome. J Neurol Neurosurg Psychiatry. 2003; 74(10):1382-1386.
38. Fulle S, Mecocci P, Fanó G, et al. Specific oxidative alterations in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome. Free Radic Biol Med. 2000;29(12):1252-1259.
39. Gupta S. Molecular signaling in death receptor and mitochondrial pathways of apoptosis (review). Int J Oncol. 2003;22(1):15-20.
40. Stewart JM, Gewitz MH, Weldon A, Arlievsky N, Li K, Munoz J. Orthostatic intolerance in adolescent chronic fatigue syndrome. Pediatrics. 1999;103(1): 116-121. (Pubitemid 29281937)
41. Wyller VB, Saul JP, Walløe L, Thaulow E. Sympathetic cardiovascular control during orthostatic stress and isometric exercise in adolescent chronic fatigue syndrome. Eur J Appl Physiol. 2008;102(6):623-632.
42. van de Putte EM, Uiterwaal CSPM, Bots ML, Kuis W, Kimpen JLL, Engelbert RHH. Is chronic fatigue syndrome a connective tissue disorder? a cross-sectional study in adolescents. Pediatrics. 2005;115(4):e415-e422. doi:10.1542/peds.2004- 1515.
43. Weber T, Auer J, O'Rourke MF, et al. Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions. Eur Heart J. 2005;26(24):2657-2663. (Pubitemid 41746688)
44. Khan F, Green FC, Forsyth JS, Greene SA, Morris AD, Belch JJF. Impaired microvascular function in normal children: effects of adiposity and poor glucose handling. J Physiol. 2003;551(Pt 2):705-711. (Pubitemid 37121725)
45. Elhadd TA, Kennedy G, Hill A, et al. Abnormal markers of endothelial cell activation and oxidative stress in children, adolescents and young adults with type 1 diabetes with no clinical vascular disease. Diabetes Metab Res Rev. 1999;15 (6):405-411.
46. Klimas NG, Koneru AO. Chronic fatigue syndrome: inflammation, immune function, and neuroendocrine interactions. Curr Rheumatol Rep. 2007;9(6):482-487.
47. Lombardi VC, Ruscetti FW, Das Gupta J, et al. Detection of an infectious retro-virus, XMRV, in blood cells of patients with chronic fatigue syndrome. Science. 2009;326(5952):585-589.