Severe degeneration of peripheral motor axons after spinal cord injury: A European multicenter study in 345 patients

Neurorehabilitation and Neural Repair

Volumn 24, Issue 7, 2010, Pages 657-665

  Van De Meent, Hendrik ^a   Hosman, Allard Jf ^a   Hendriks, Jan ^a   Zwarts, MacHiel ^a   Schubert, Martin ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b BALGRIST UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

electromyography; nerve degeneration; peripheral nerve; spinal cord injury

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CERVICAL SPINAL CORD INJURY; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOTOR NERVE; MUSCLE ACTION POTENTIAL; NERVE DEGENERATION; NERVE FUNCTION; PERIPHERAL NERVE; SPINAL CORD INJURY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AXONS; EUROPE; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR NEURONS; PERIPHERAL NERVOUS SYSTEM DISEASES; PROSPECTIVE STUDIES; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; WALLERIAN DEGENERATION; YOUNG ADULT;

EID: 77956385543     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968310368534     Document Type: Article

References (16)

1. Laurence TN, Pugel AV, Teasdall RD Peripheral nerve involvement in spinal cord injury: an electromyographic study. Arch Phys Med Rehabil. 1978 ; 59: 309-313.
2. Blaik Z., McGarry J., Daura R. Peripheral neuropathy in spinal cord injured patients. Electromyogr Clin Neurophysiol. 1989 ; 29: 469-472.
3. Aisen ML, Brown W., Rubin M. Electrophysiologic changes in lumbar spinal cord after cervical cord injury. Neurology. 1992 ; 42: 623-626.
4. Berman SA, Young RR, Sarkarati M., Shefner JM Injury zone denervation in traumatic quadriplegia in humans. Muscle Nerve. 1996 ; 19: 701-706.
5. Rutz S., Dietz V., Curt A. Diagnostic and prognostic value of compound motor action potential of lower limbs in acute paraplegic patients. Spinal Cord. 2000 ; 38: 203-210.
6. Kirshblum S., Lim S., Garstang S., Millis S. Electrodiagnostic changes of the lower limbs in subjects with chronic complete cervical spinal cord injury. Arch Phys Med Rehabil. 2001 ; 82: 604-607.
7. Nogajski HJ, Engel S., Kiernan MC Focal and generalized peripheral nerve dysfunction in spinal cord injured patients. J Clin Neurophysiol. 2006 ; 23: 273-279.
8. Lin CS, Macefield VG, Elam M., Wallin BG, Engel S., Kiernan MC Axonal changes in spinal cord injured patients distal to the site of injury. Brain. 2007 ; 130: 985-994.
9. McComas AJ, Sica RE, Upton AR, Aguilera N. Functional changes in motoneurones of hemiparetic patients. J Neurol Neurosurg Psychiatry. 1973 ; 36: 183-193.
10. Benecke R., Berthold A., Conrad B. Denervation activity in the EMG of patients with upper motor neuron lesions: time course, local distribution and pathogenetic aspects. J Neurol. 1983 ; 230: 143-151.
11. Maynard FM Jr, Bracken MB, Creasey G., et al. International Standards for Neurological and Functional Classification of Spinal Cord Injury. American Spinal Injury Association. Spinal Cord. 1997 ; 35: 266-274.
12. DeLisa JA, Lee HJ, Baran EM, Lai K., Spielholz N., Mackenzie K. Manual of Nerve Conduction Velocity and Clinical Neurophysiology. 3 rd ed. New York, NY: Raven Press ; 1987.
13. Boland RA, Bostock H., Kiernan MC Plasticity of lower limb motor axons after cervical cord injury. Clin Neurophysiol. 2009 ; 120: 204-209.
14. Urso ML, Clarkson PM, Price TB Immobilization effects in young and older adults. Eur J Appl Physiol. 2006 ; 96: 564-571.
15. Chang CW Evident trans-synaptic degeneration of motor neurons after stroke: a study of neuromuscular jitter by axonal microstimulation. Electroencephalogr Clin Neurophysiol. 1998 ; 109: 199-202.
16. Kuijk AA, Pasman JW, Hendricks HT, Schelhaas J., Zwarts JZ, Geurts ACH Supratentorial ischemic stroke: more than an upper motor neuron disorder. J Clin Neurophysiol. 2007 ; 24: 450-455.