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Volumn 120, Issue 9, 2010, Pages 3084-3087

New players in the sepsis-protective activated protein C pathway

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; DROTRECOGIN; ENDOTHELIAL PROTEIN C RECEPTOR; PROTEINASE ACTIVATED RECEPTOR 1;

EID: 77956371316     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI44266     Document Type: Note
Times cited : (28)

References (22)
  • 1
    • 0037036069 scopus 로고    scopus 로고
    • Activation of endothelial cell protease activated receptor 1 by the protein C pathway
    • Riewald M, Petrovan RJ, Donner A, Mueller BM, Ruf W. Activation of endothelial cell protease activated receptor 1 by the protein C pathway. Science. 2002;296(5574):1880-1882.
    • (2002) Science , vol.296 , Issue.5574 , pp. 1880-1882
    • Riewald, M.1    Petrovan, R.J.2    Donner, A.3    Mueller, B.M.4    Ruf, W.5
  • 2
    • 17044427680 scopus 로고    scopus 로고
    • Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation
    • Feistritzer C, Riewald M. Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation. Blood. 2005;105(8):3178-3184.
    • (2005) Blood , vol.105 , Issue.8 , pp. 3178-3184
    • Feistritzer, C.1    Riewald, M.2
  • 3
    • 21244502159 scopus 로고    scopus 로고
    • Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling
    • Riewald M, Ruf W. Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling. J Biol Chem. 2005;280(20):19808-19814.
    • (2005) J Biol Chem , vol.280 , Issue.20 , pp. 19808-19814
    • Riewald, M.1    Ruf, W.2
  • 4
    • 65549087489 scopus 로고    scopus 로고
    • Caveolae are required for protease-selective signaling by protease-activated receptor-1
    • Russo A, Soh UJ, Paing MM, Arora P, Trejo J. Caveolae are required for protease-selective signaling by protease-activated receptor-1. Proc Natl Acad Sci U S A. 2009;106(15):6393-6397.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.15 , pp. 6393-6397
    • Russo, A.1    Soh, U.J.2    Paing, M.M.3    Arora, P.4    Trejo, J.5
  • 5
    • 37049012509 scopus 로고    scopus 로고
    • The ligand occupancy of endothelial protein C receptor switches the PAR-1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells
    • Bae JS, Yang L, Manithody C, Rezaie AR. The ligand occupancy of endothelial protein C receptor switches the PAR-1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells. Blood. 2007;110(12):3909-3916.
    • (2007) Blood , vol.110 , Issue.12 , pp. 3909-3916
    • Bae, J.S.1    Yang, L.2    Manithody, C.3    Rezaie, A.R.4
  • 6
    • 34948866150 scopus 로고    scopus 로고
    • Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C
    • Kerschen EJ, et al. Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. J Exp Med. 2007;204(10):2439-2448.
    • (2007) J Exp Med , vol.204 , Issue.10 , pp. 2439-2448
    • Kerschen, E.J.1
  • 7
    • 67651083688 scopus 로고    scopus 로고
    • Hyper-antithrombotic, non-cyto protective Glu149Ala-activated protein C mutant
    • Mosnier LO, et al. Hyper-antithrombotic, non-cyto protective Glu149Ala-activated protein C mutant. Blood. 2009;113(23):5970-5978.
    • (2009) Blood , vol.113 , Issue.23 , pp. 5970-5978
    • Mosnier, L.O.1
  • 8
    • 1342269932 scopus 로고    scopus 로고
    • Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3
    • Guo H, et al. Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3. Neuron. 2004;41(4):563-572.
    • (2004) Neuron , vol.41 , Issue.4 , pp. 563-572
    • Guo, H.1
  • 9
    • 58549121206 scopus 로고    scopus 로고
    • Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells
    • Yang XV, et al. Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells. Proc Natl Acad Sci U S A. 2009;106(1):274-279.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.1 , pp. 274-279
    • Yang, X.V.1
  • 10
    • 77953202368 scopus 로고    scopus 로고
    • The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b
    • Cao C, Gao Y, Li Y, Antalis TM, Castellino FJ, Zhang L. The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b. J Clin Invest. 2010;120(6):1971-1980.
    • (2010) J Clin Invest , vol.120 , Issue.6 , pp. 1971-1980
    • Cao, C.1    Gao, Y.2    Li, Y.3    Antalis, T.M.4    Castellino, F.J.5    Zhang, L.6
  • 11
    • 77956372381 scopus 로고    scopus 로고
    • + dendritic cells to reduce the mortality of endotoxemia in mice
    • + dendritic cells to reduce the mortality of endotoxemia in mice. J Clin Invest. 2010;120(9):3167-3178.
    • (2010) J Clin Invest , vol.120 , Issue.9 , pp. 3167-3178
    • Kerschen, E.1
  • 12
    • 65449167251 scopus 로고    scopus 로고
    • Recombinant human activated protein C inhibits integrin-mediated neutrophil migration
    • Elphick GF, et al. Recombinant human activated protein C inhibits integrin-mediated neutrophil migration. Blood. 2009;113(17):4078-4085.
    • (2009) Blood , vol.113 , Issue.17 , pp. 4078-4085
    • Elphick, G.F.1
  • 13
    • 34250758543 scopus 로고    scopus 로고
    • Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia
    • Zheng X, et al. Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia. J Thromb Haemost. 2007;5(7):1394-1400.
    • (2007) J Thromb Haemost , vol.5 , Issue.7 , pp. 1394-1400
    • Zheng, X.1
  • 14
    • 33845898737 scopus 로고    scopus 로고
    • Steady-state and inflammatory dendritic-cell development
    • Shortman K, Naik SH. Steady-state and inflammatory dendritic-cell development. Nat Rev Immunol. 2007;7(1):19-30.
    • (2007) Nat Rev Immunol , vol.7 , Issue.1 , pp. 19-30
    • Shortman, K.1    Naik, S.H.2
  • 15
    • 77953498509 scopus 로고    scopus 로고
    • Found in translation: The human equivalent of mouse CD8+ dendritic cells
    • Villadangos JA, Shortman K. Found in translation: the human equivalent of mouse CD8+ dendritic cells. J Exp Med. 2010;207(6):1131-1134.
    • (2010) J Exp Med , vol.207 , Issue.6 , pp. 1131-1134
    • Villadangos, J.A.1    Shortman, K.2
  • 16
    • 33750288937 scopus 로고    scopus 로고
    • Apoptosis and caspases regulate death and inflammation in sepsis
    • Hotchkiss RS, Nicholson DW. Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol. 2006;6(11):813-822.
    • (2006) Nat Rev Immunol , vol.6 , Issue.11 , pp. 813-822
    • Hotchkiss, R.S.1    Nicholson, D.W.2
  • 17
    • 70449107044 scopus 로고    scopus 로고
    • Extracellular histones are major mediators of death in sepsis
    • Xu J, et al. Extracellular histones are major mediators of death in sepsis. Nat Med. 2009;15(11):1318-1321.
    • (2009) Nat Med , vol.15 , Issue.11 , pp. 1318-1321
    • Xu, J.1
  • 18
    • 55349136265 scopus 로고    scopus 로고
    • Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells
    • Kang SJ, Liang HE, Reizis B, Locksley RM. Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells. Immunity. 2008;29(5):819-833.
    • (2008) Immunity , vol.29 , Issue.5 , pp. 819-833
    • Kang, S.J.1    Liang, H.E.2    Reizis, B.3    Locksley, R.M.4
  • 19
    • 40749112792 scopus 로고    scopus 로고
    • Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10
    • Pereira C, Schaer DJ, Bachli EB, Kurrer MO, Schoedon G. Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10. Arterioscler Thromb Vasc Biol. 2008;28(3):504-510.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.3 , pp. 504-510
    • Pereira, C.1    Schaer, D.J.2    Bachli, E.B.3    Kurrer, M.O.4    Schoedon, G.5
  • 20
    • 33746888276 scopus 로고    scopus 로고
    • Modulation of monocyte function by activated protein C, a natural anticoagulant
    • Stephenson DA, Toltl LJ, Beaudin S, Liaw PC. Modulation of monocyte function by activated protein C, a natural anticoagulant. J Immunol. 2006;177(4):2115-2122.
    • (2006) J Immunol , vol.177 , Issue.4 , pp. 2115-2122
    • Stephenson, D.A.1    Toltl, L.J.2    Beaudin, S.3    Liaw, P.C.4
  • 21
    • 33646581395 scopus 로고    scopus 로고
    • Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration
    • Cao C, et al. Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J. 2006;25(9):1860-1870.
    • (2006) EMBO J , vol.25 , Issue.9 , pp. 1860-1870
    • Cao, C.1
  • 22
    • 10244229104 scopus 로고    scopus 로고
    • Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis
    • Nick JA, et al. Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis. Blood. 2004;104(13):3878-3885.
    • (2004) Blood , vol.104 , Issue.13 , pp. 3878-3885
    • Nick, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.