Confocal fluctuation spectroscopy and imaging

Current Pharmaceutical Biotechnology

Volumn 11, Issue 6, 2010, Pages 639-653

  Földes Papp, Zeno ^a,b   Liao, Shih Chu Jeff ^a   You, Tiefeng ^a   Terpetschnig, Ewald ^a   Barbieri, Beniamino ^a  

^a ISS   (United States)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Brownian motion; Fast FLIM; FLIM; Fluctuation imaging; Fluctuation microscopy; Fluctuation spectroscopy; How to do approach; Lifetime imaging; Live cell; Optimized ISS fluorescence fluctuation system ALBA JZ ; Physical concepts; Singlemolecule detection in dilute solution

Indexed keywords

ARTICLE; FLUORESCENCE; HYDRODYNAMICS; IMAGING; IMMOBILIZATION; MICROSCOPY; PHOTON; PHYSICS; SIGNAL NOISE RATIO; SIGNAL TRANSDUCTION; SPATIAL AUTOCORRELATION ANALYSIS; SPECTROSCOPY; TECHNOLOGY; ANIMAL; BIOLOGICAL MODEL; CHEMICAL MODEL; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SIMULATION; FLUORESCENCE MICROSCOPY; HUMAN; METHODOLOGY; MOLECULAR IMAGING;

ANIMALS; COMPUTER SIMULATION; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MOLECULAR IMAGING;

EID: 77956367197     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920110792246618     Document Type: Article

References (35)

1. Földes-Papp, Z.; Liao, S.-C. J.; You. T.; Barbieri, B. Reducing background contributions in fluorescence fluctuation time-traces for single-molecule measurements in solution. Curr. Pharm. Biotechnol. 2009, 10 (5), 532-542.
2. Földes-Papp, Z. Viral chip technology in genomic medicine, Chap 48. In: Genomic and Personalized Medicine. Willard, H.F.; Gins burg, M., Eds.; Academic Press: New York, 2009; Vol. 2, pp. 538-561.
3. Földes-Papp, Z. What it means to measure a single molecule in a solution by fluorescence fluctuation spectroscopy. Exp. Mol. Pathol. 2006, 80. 209-218.
4. Földes-Papp, Z. Fluorescence fluctuation spectroscopic approaches to the study of a single molecule diffusing in solution and a live cell without systemic drift or convection: a theoretical study. Curr. Pharm. Biotechnol. 2007, 8. 261-273.
5. Minsky, M. Microscopy apparatus. U.S. patent 3,013,467, Filed November 7, 1957, Patented December 19. 1961.
6. Brakenhoff, G.J.; Blom, P.; Barends. P. Confocal scanning light microscopy with high aperture immersion lenses. J. Microsc., (Oxf.), 1979, 117, 219-232.
7. Brakenhoff, G.J.; van der Voort, H.T.M.; van Sprousen, E.A.; Linnemann, W.A.M.; Nanninga, N. Three-dimensional chromatin distribution in neuroblastoma nuclei shown by confocal scanning laser microscopy. Nature, 1985, 317, 748-749.
8. White, J.G.; Amos, W.B.; Fordham, M. An evaluation of confocal versus conventional imaging of biological structures by fluorescence light microscopy. J. Cell Biol., 1987, 106. 41-48.
9. Rigler, R.; Mets, Ü. Diffusion of single molecules through a Gaussian laser beam. SPIE, 1992, 1921, 239-248.
10. Rigler, R.; Mets, Ü.; Widengren, J.; Kask, P. Fluorescence correlation spectroscopy with high count rate and low background: analysis of translational diffusion. Eur. Biophys. J. 1993, 22, 169-175.
11. Mets, Ü.; Rigler, R. Submillisecond detection of single rhodamine molecules in water. J. Fluoresc., 1994, 4. 259-264.
12. Magde, D.; Elson, E.L.; Webb, W.W. Thermodynamic fluctuations in a reaction system-measurements by fluorescence correlation spectroscopy. Phys. Rev. Lett., 1972, 29. 705-708.
13. Elson, E.L.; Magde, D. Fluorescence correlation spectroscopy. I. Conceptional basis and theory. Biopolymers. 1974, 13. 1-27.
14. Ehrenberg, M.; Rigler, R. Rotational brownian motion and fluorescence intensity fluctuations. Chem. Phys., 1974, 4, 390-401.
15. Arago, S.R.; Pecora, R. Fluorescence correlation spectroscopy as a probe of molecular dynamics. J. Chem. Phys. 1976, 64, 1791-1803.
16. Koppel, D.W. Statistical accuracy in fluorescence correlation spectroscopy. Phys. Rev., 1974, 10, 1938-1945.
17. Special Issue: Frontiers in chemistry: single molecules. Science, 1999, 283, 1667-1698.
18. Földes-Papp, Z. 'True' single-molecule molecule observations by fluorescence correlation spectroscopy and two-color fluorescence cross-correlation spectroscopy. Exp. Mol. Pathol., 2007, 82, 147-155.
19. Földes-Papp, Z.; Baumann, G.; Kinjo, M.; Tamura, M. Singlephase single-molecule fluorescence correlation spectroscopy (SPSM-FCS). In: Encyclopedia of Medical Genomics & Proteomics. Fuchs, J.; Podda, M., Eds.; Marcel Dekker: New York, 2005.
20. Dyson, F. Imagined Worlds. Harvard University Press: Cambridge, MA, 1997.
21. Einstein, A. Über die von der molekular-kinetischen Theorie der Wärme geforderte Bewegung von in ruhenden Flüssigkeiten suspendierten Teilchen (The motion of elements in static liquids as claimed in the molecular kinetic theory of heat). Ann. Phys., (Leipzig). 1905, 17. 549-560.
22. Einstein, A. Zur Theorie der Brownschen Bewegung, Ann. Phys., (Leipzig), 1906, 19, 371-381.
23. Rigler, R.; Földes-Papp, Z.; Meyer-Almes, F.-J., Sammet, C.; Völcker, M.; Schnetz, A. Fluorescence cross-correlation: a new concept for polymerase chain reaction. J. Biotechnol., 1998, 63, 97-109.
24. Földes-Papp, Z. How the molecule number is correctly quantified in two-color fluorescence cross-correlation spectroscopy: correction for cross-talk and quenching in experiments. Curr. Pharm. Biotechnol. 2005, 6 (6), 437-444.
25. Block, S.M. Getting high on single molecule biophysics. Curr. Pharm. Biotechnol. 2009, 10 (5), 464-466.
26. ndFebruary 2010. http://www.scitopics.com/authorprofile. jsp?userid=1113 [Accessed February 2, 2010].
27. Clayton, A.H. A; Hanley, Q.S.; Verveer, P.J. Graphical representation and multicomponent analysis of single-frequency fluorescence lifetime imaging microscopy data. J. Microsc., 2004, 213. 1-5.
28. Redford, G.I.; Clegg, R. Polar plot representation for frequencydomain analysis of fluorescence lifetimes. J. Fluoresc. 2005, 15. 805-815.
29. Colyer, R.A.; Lee, C.; Gratton, E. A novel fluorescence lifetime imaging system that optimizes photon efficiency. Microsc. Res. Tech., 2008, 71. 201-213.
30. Barreiro, O.; Zamai, M.; Yáñez-Mó, M.; Tejera, E.; López-Romero, P.; Monk, P.N.; Gratton, E.; Caiolfa, V.R.; Sánchez-Madrid, F. Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J. Cell Biol., 2008, 183(3), 527-542.
31. Caiolfa, V.R.; Zamai, M.; Malengo, G.; Andolfo, G.A.; Madsen, C.D.; Sutin, J.; Digman, M.A.; Gratton, E.; Blasi, F.; Sidenius, N. Monomer dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies. J. Cell Biol. 2007, 179, 1067-1082.
32. Digman, M.A.; Caiolfa, V.R.M.; Zamai, M.; Gratton, E. The phasor approach to fluorescence lifetime imaging analysis. Biophys. J. 2008, 94. L14-L16.
33. Földes-Papp, Z.; König. K.; Studier, H.; Bückle, R.; Breunig, H.G.; Uchugonova, A.; Kostner, G.M. Trafficking of mature miRNA-122 into the nucleus of live liver cells. Curr. Pharm. Biotechnol. 2009, 10 (6), 569-578.
34. Földes-Papp, Z. Exploring the biomedical applications of microscopy and spectroscopy. Exp. Mol. Pathol., 2007, 82(2), 103.
35. Baumann, G.; Place, R.F.; Földes-Papp, Z. Meaningful interpretation of subdiffusive measurements in living cells (crowded environment) by fluorescence fluctuation miscroscopy. Curr. Pharm. Biotechnol., 2010, 11(5), 427-493.