Animal and human antibodies to distinct Staphylococcus aureus antigens mutually neutralize opsonic killing and protection in mice

Journal of Clinical Investigation

Volumn 120, Issue 9, 2010, Pages 3220-3233

  Skurnik, David ^a   Merighi, Massimo ^b,e   Grout, Martha ^a   Gadjeva, Mihaela ^a   Maira Litran, Tomas ^a   Ericsson, Maria ^b   Goldmann, Donald A ^c   Huang, Susan S ^d   Datta, Rupak ^d   Lee, Jean C ^a   Pier, Gerald B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Glycosyn Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; BACTERIAL ANTIGEN; CAPSULAR POLYSACCHARIDE; MONOCLONAL ANTIBODY; OPSONIN; POLY N ACETYL GLUCOSAMINE; POLYCLONAL ANTISERUM; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOSIS; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; COMPLEMENT DEPOSITION; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; HUMAN; IMMUNITY; IMMUNIZATION; ISOTHERMAL TITRATION CALORIMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCAL BACTEREMIA; STAPHYLOCOCCAL PNEUMONIA; STAPHYLOCOCCAL SKIN INFECTION; STAPHYLOCOCCUS AUREUS; SURFACE PLASMON RESONANCE;

ACETYLGLUCOSAMINE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIGENS, BACTERIAL; BACTEREMIA; CROSS INFECTION; FEMALE; HUMANS; MICE; OPSONIN PROTEINS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 77956359686     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI42748     Document Type: Article

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