Design and synthesis of fluorine-substituted 3-hydroxypyridin-4-ones

Tetrahedron Letters

Volumn 51, Issue 40, 2010, Pages 5230-5233

  Ma, Yong Min ^a   Hider, Robert C ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 FLUORO 3 HYDROXYPYRIDIN 4 ONE DERIVATIVE; 3 HYDROXY 4 PYRIDONE DERIVATIVE; 5 FLUORO 3 HYDROXYPYRIDIN 4 ONE DERIVATIVE; 5 FLUORO 3 HYDROXYPYRIDINE 4 ONE DERIVATIVE; DEFERIPRONE; FLUORINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 77956341520     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.07.134     Document Type: Article

References (19)

1. J.B. Porter Semin. Hematol. 38 2001 63 68
2. S. Singh, R.O. Epemolu, P.S. Dobbin, G.S. Tilbrook, B.L. Ellis, L.A. Damani, and R.C. Hider Drug Metab. Dispos. 20 1992 256 261
3. C. Rafat, F. Fakhouri, J.A. Ribeil, R. Delarue, and Q.M. Le Am. J. Kidney Dis. 54 2009 931 934
4. M.D. Cappellini, and P. Pattoneri Annu. Rev. Med. 60 2009 25 38
5. W.R. Dolbier J. Fluorine Chem. 126 2005 157 163
6. H.J. Bohm, D. Banner, S. Bendels, M. Kansy, B. Kuhn, K. Muller, U. Obst-Sander, and M. Stahl ChemBioChem 5 2004 637 643
7. I. Yamazaki, T. Taguchi, and L. Ojima L. Ojima, Fluorine in Medicinal Chemistry and Chemical Biology, Unique Properties of Fluorine and their Relevance to Medicinal Chemistry and Chemical Biology 2009 John Wiley & Sons Chichester 3 46
8. G.S. Lal, G.P. Pez, and R.G. Syvret Chem. Rev. 96 1996 1737 1755
9. P.T. Nyffeler, S.G. Duron, M.D. Burkart, S.P. Vincent, and C.H. Wong Angew. Chem., Int. Ed. 44 2005 192 212
10. R.G. Syvret, K.M. Butt, T.P. Nguyen, V.L. Bulleck, and R.D. Rieth J. Org. Chem. 67 2002 4487 4493
11. A. Rostami Synlett 2007 2924 2925
12. C. Bobbio, and M. Schlosser J. Org. Chem. 70 2005 3039 3045
13. L. Estel, F. Marsais, and G. Quéguiner J. Org. Chem. 53 1988 2740 2744
14. F. Mongin, F. Trecourt, O. Mongin, and G. Quéguiner Tetrahedron 58 2002 309 314
15. F. Mongin, F. Trecourt, B. Gervais, O. Mongin, and G. Quéguiner J. Org. Chem. 67 2002 3272 3276
16. P. Gros, Y. Fort, and P. Caubere J. Chem. Soc., Perkin Trans. 1 1997 3071 3080
17. M. Schlosser, and F. Mongin Chem. Soc. Rev. 36 2007 1161 1172
18. 2 (80 ml) and the extract dried and concentrated. The residue was purified by chromatography to give the desired products.
19. +, 144.0461. Found, 144.0468.