Association of age-related macular degeneration with polymorphisms in vascular endothelial growth factor and its receptor

Ophthalmology

Volumn 117, Issue 9, 2010, Pages 1769-1774

  Galan, Alessandro ^a   Ferlin, Alberto ^b   Caretti, Luigi ^a   Buson, Genny ^b   Sato, Giovanni ^a   Frigo, Anna Chiara ^b   Foresta, Carlo ^b  

^a S ANTONIO HOSPITAL   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; GLYCINE; THREONINE; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR;

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENETIC MARKER; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; INTRON; KDR GENE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; RETINA MACULA AGE RELATED DEGENERATION; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; ALLELES; CASE-CONTROL STUDIES; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; INTRONS; MACULAR DEGENERATION; MALE; MIDDLE AGED; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 77956340398     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ophtha.2010.01.030     Document Type: Article

References (14)

1. R. Klein, B.E. Klein, and S.C. Jensen Age-related maculopathy in a multiracial United States population: the National Health and Nutrition Examination Survey III Ophthalmology 106 1999 1056 1065
2. T. Ayoub, and N. Patel Age-related macular degeneration J R Soc Med 102 2009 56 61
3. P.J. Rosenfeld, D.M. Brown, J.S. Heier MARINA Study Group Ranibizumab for neovascular age-related macular degeneration N Engl J Med 355 2006 1419 1431
4. C.O. Phillips, and E.J. Higginbotham Multivitamin supplements, ageing, and loss of vision: seeing through the shadows Arch Intern Med 169 2009 1180 1182
5. D.J. Hicklin, and L.M. Ellis Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis J Clin Oncol 23 2005 1011 1027
6. J.S. Penn, A. Madan, and R.B. Caldwell Vascular endothelial growth factor in eye disease Prog Retin Eye Res 27 2008 331 371
7. A.J. Churchill, J.G. Carter, and H.C. Lovell VEGF polymorphisms are associated with neovascular age-related macular degeneration Hum Mol Genet 15 2006 2955 2961
8. J.L. Haines, N. Schnetz-Boutaud, and S. Schmidt Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6 Invest Ophthalmol Vis Sci 47 2006 329 335
9. A.J. Richardson, F.M. Islam, and R.H. Guymer A tag-single nucleotide polymorphisms approach to the vascular endothelial growth factor-A gene in age-related macular degeneration Mol Vis 13 2007 2148 2152 [serial online] http://www.molvis.org/molvis/v13/a244/ Accessed December 16, 2009.
10. J.M. Lin, L. Wan, and Y.Y. Tsai Vascular endothelial growth factor gene polymorphisms in age-related macular degeneration Am J Ophthalmol 145 2008 1045 1051
11. S.S. Boekhoorn, A. Isaacs, and A.G. Uitterlinden Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration: the Rotterdam Study Ophthalmology 115 2008 1899 1903
12. G.J. McKay, G. Silvestri, and N. Orr VEGF and age-related macular degeneration [letter] Ophthalmology 116 2009 1227
13. R. Klein, B.E. Klein, and K.L. Linton Prevalence of age-related maculopathy: the Beaver Dam Eye Study Ophthalmology 99 1992 933 943
14. Y. Wang, Y. Zheng, and W. Zhang Polymorphisms of KDR gene are associated with coronary heart disease J Am Coll Cardiol 50 2007 760 767