Drosophila Dscam Proteins Regulate Postsynaptic Specificity at Multiple-Contact Synapses

Neuron

Volumn 67, Issue 5, 2010, Pages 761-768

  Millard, S Sean ^a   Lu, Zhiyuan ^b   Zipursky, S Lawrence ^a   Meinertzhagen, Ian A ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA PROTEIN; PROTEIN DSCAM1; PROTEIN DSCAM2; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; DSCAM PROTEIN, DROSOPHILA; DSCAM2 PROTEIN, DROSOPHILA; NERVE CELL ADHESION MOLECULE;

ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DROSOPHILA; GENE EXPRESSION REGULATION; GENE MUTATION; HETEROZYGOSITY; HOMOZYGOSITY; MITOTIC RECOMBINATION; NONHUMAN; PHENOTYPE; PHOTORECEPTOR; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SYNAPSE; SYNAPTOGENESIS; ANIMAL; CLASSIFICATION; CYTOLOGY; GENETICS; METABOLISM; MUTATION; NERVE CELL; PHYSIOLOGY; PROCEDURES; TRANSGENIC ANIMAL; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; VISUAL SYSTEM;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL ADHESION MOLECULES; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; NEURONS; SYNAPSES; VISUAL PATHWAYS; NEURAL CELL ADHESION MOLECULES;

EID: 77956324498     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2010.08.030     Document Type: Article

References (39)

1. Andrews G.L., Tanglao S., Farmer W.T., Morin S., Brotman S., Berberoglu M.A., Price H., Fernandez G.C., Mastick G.S., Charron F., Kidd T. Dscam guides embryonic axons by Netrin-dependent and -independent functions. Development 2008, 135:3839-3848.
2. Clandinin T.R., Zipursky S.L. Making connections in the fly visual system. Neuron 2002, 35:827-841.
3. Dowling J.E., Boycott B.B. Organization of the primate retina: electron microscopy. Proc. R Soc. Lond. B Biol. Sci. 1966, 166:80-111.
4. Fiala J.C. Reconstruct: a free editor for serial section microscopy. J. Microsc. 2005, 218:52-61.
5. Fröhlich A., Meinertzhagen I.A. Quantitative features of synapse formation in the fly's visual system. I. The presynaptic photoreceptor terminal. J. Neurosci. 1983, 3:2336-2349.
6. Fuerst P.G., Koizumi A., Masland R.H., Burgess R.W. Neurite arborization and mosaic spacing in the mouse retina require DSCAM. Nature 2008, 451:470-474.
7. Fuerst P.G., Bruce F., Tian M., Wei W., Elstrott J., Feller M.B., Erskine L., Singer J.H., Burgess R.W. DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina. Neuron 2009, 64:484-497.
8. Gao S., Takemura S.Y., Ting C.Y., Huang S., Lu Z., Luan H., Rister J., Thum A.S., Yang M., Hong S.T., et al. The neural substrate of spectral preference in Drosophila. Neuron 2008, 60:328-342.
9. Hall D.H., Russell R.L. The posterior nervous system of the nematode Caenorhabditis elegans: serial reconstruction of identified neurons and complete pattern of synaptic interactions. J. Neurosci. 1991, 11:1-22.
10. Hardie R.C. Is histamine a neurotransmitter in insect photoreceptors?. J. Comp. Physiol. [A] 1987, 161:201-213.
11. Hattori D., Demir E., Kim H.W., Viragh E., Zipursky S.L., Dickson B.J. Dscam diversity is essential for neuronal wiring and self-recognition. Nature 2007, 449:223-227.
12. Hughes M.E., Bortnick R., Tsubouchi A., Bäumer P., Kondo M., Uemura T., Schmucker D. Homophilic Dscam interactions control complex dendrite morphogenesis. Neuron 2007, 54:417-427.
13. Lee T., Luo L. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 1999, 22:451-461.
14. Lee C.H., Herman T., Clandinin T.R., Lee R., Zipursky S.L. N-cadherin regulates target specificity in the Drosophila visual system. Neuron 2001, 30:437-450.
15. Li H.L., Huang B.S., Vishwasrao H., Sutedja N., Chen W., Jin I., Hawkins R.D., Bailey C.H., Kandel E.R. Dscam mediates remodeling of glutamate receptors in Aplysia during de novo and learning-related synapse formation. Neuron 2009, 61:527-540.
16. Liu G., Li W., Wang L., Kar A., Guan K.L., Rao Y., Wu J.Y. DSCAM functions as a netrin receptor in commissural axon pathfinding. Proc. Natl. Acad. Sci. USA 2009, 106:2951-2956.
17. Ly A., Nikolaev A., Suresh G., Zheng Y., Tessier-Lavigne M., Stein E. DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell 2008, 133:1241-1254.
18. Matthews B.J., Kim M.E., Flanagan J.J., Hattori D., Clemens J.C., Zipursky S.L., Grueber W.B. Dendrite self-avoidance is controlled by Dscam. Cell 2007, 129:593-604.
19. Meinertzhagen I.A. Ultrastructure and quantification of synapses in the insect nervous system. J. Neurosci. Methods 1996, 69:59-73.
20. Meinertzhagen I.A., Hanson T.E. The Development of Drosophila melanogaster 1993, Volume 2. Cold Spring Harbor Laboratory Press, New York.
21. Meinertzhagen I.A., O'Neil S.D. Synaptic organization of columnar elements in the lamina of the wild type in Drosophila melanogaster. J. Comp. Neurol. 1991, 305:232-263.
22. Meinertzhagen I.A., Sorra K.E. Synaptic organization in the fly's optic lamina: few cells, many synapses and divergent microcircuits. Prog. Brain Res. 2001, 131:53-69.
23. Meinertzhagen I.A., Piper S.T., Sun X.-J., Fröhlich A. Neurite morphogenesis of identified visual interneurons and its relationship to photoreceptor synaptogenesis in the flies, Musca domestica and Drosophila melanogaster. Europ. J. Neurosci. 2000, 12:1342-1356.
24. Millard S.S., Flanagan J.J., Pappu K.S., Wu W., Zipursky S.L. Dscam2 mediates axonal tiling in the Drosophila visual system. Nature 2007, 447:720-724.
25. Neves G., Zucker J., Daly M., Chess A. Stochastic yet biased expression of multiple Dscam splice variants by individual cells. Nat. Genet. 2004, 36:240-246.
26. Peters A., Palay S.L., Webster H.deF. The Fine Structure of the Nervous System: Neurons and Their Supporting Cells 1991, Oxford University Press, New York. Third Edition.
27. Prokop A., Meinertzhagen I.A. Development and structure of synaptic contacts in Drosophila. Semin. Cell Dev. Biol. 2006, 17:20-30.
28. Rister J., Pauls D., Schnell B., Ting C.Y., Lee C.H., Sinakevitch I., Morante J., Strausfeld N.J., Ito K., Heisenberg M. Dissection of the peripheral motion channel in the visual system of Drosophila melanogaster. Neuron 2007, 56:155-170.
29. Schmucker D., Clemens J.C., Shu H., Worby C.A., Xiao J., Muda M., Dixon J.E., Zipursky S.L. Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell 2000, 101:671-684.
30. Shaw S.R., Meinertzhagen I.A. Evolutionary progression at synaptic connections made by identified homologous neurones. Proc. Natl. Acad. Sci. USA 1986, 83:7961-7965.
31. Soba P., Zhu S., Emoto K., Younger S., Yang S.J., Yu H.H., Lee T., Jan L.Y., Jan Y.N. Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization. Neuron 2007, 54:403-416.
32. Takemura S.Y., Lu Z., Meinertzhagen I.A. Synaptic circuits of the Drosophila optic lobe: the input terminals to the medulla. J. Comp. Neurol. 2008, 509:493-513.
33. Vogt A.K., Brewer G.J., Decker T., Böcker-Meffert S., Jacobsen V., Kreiter M., Knoll W., Offenhäusser A. Independence of synaptic specificity from neuritic guidance. Neuroscience 2005, 134:783-790.
34. Wang J., Zugates C.T., Liang I.H., Lee C.H., Lee T. Drosophila Dscam is required for divergent segregation of sister branches and suppresses ectopic bifurcation of axons. Neuron 2002, 33:559-571.
35. White J.G., Southgate E., Thomson J.N., Brenner S. The structure of the nervous system of the nematode C. elegans. Philos. Trans. R. Soc. Lond. B Biol. Sci. 1986, 314:1-340.
36. Wojtowicz W.M., Flanagan J.J., Millard S.S., Zipursky S.L., Clemens J.C. Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding. Cell 2004, 118:619-633.
37. Wojtowicz W.M., Wu W., Andre I., Qian B., Baker D., Zipursky S.L. A vast repertoire of Dscam binding specificities arises from modular interactions of variable Ig domains. Cell 2007, 130:1134-1145.
38. Yamagata M., Sanes J.R. Dscam and Sidekick proteins direct lamina-specific synaptic connections in vertebrate retina. Nature 2008, 451:465-469.
39. Zhan X.L., Clemens J.C., Neves G., Hattori D., Flanagan J.J., Hummel T., Vasconcelos M.L., Chess A., Zipursky S.L. Analysis of Dscam diversity in regulating axon guidance in Drosophila mushroom bodies. Neuron 2004, 43:673-686.