Linkage analysis of discrete traits

Cold Spring Harbor Protocols

Volumn 5, Issue 2, 2010, Pages

  Borecki, Ingrid B ^a   Rice, John P ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME ANALYSIS; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC MARKER; GENETIC MODEL; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; LINKAGE ANALYSIS; MATHEMATICAL ANALYSIS; NONPARAMETRIC TEST; PEDIGREE ANALYSIS; PHENOTYPE;

EID: 77956291510     PISSN: None     EISSN: 15596095     Source Type: Journal    
DOI: 10.1101/pdb.top69     Document Type: Article

References (28)

1. Abecasis GR, Cherny SS, Cookson WO, Cardon LR. 2002. Merlin-rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 30: 97-101.[Medline]
2. Clerget-Darpoux F, Bonaiti-Pellie C, Hochez J. 1986. Effects of misspecifying genetic parameters in lod score analysis. Biometrics 42: 393-399.[Medline]
3. Cottingham RW Jr, Idury RM, Schäffer AA. 1993. Faster sequential genetic linkage computations. AM J HUM GENET 53: 252-263.[Medline]
4. Elston R, Stewart J. 1971. A general model for the genetic analysis of pedigree data. Hum Hered 21: 523-542.[Medline]
5. Faraway JJ. 1993. Distribution of the admixture test for the detection of linkage under heterogeneity. Genet Epidemiol 10: 75-83.[Medline]
6. Greenberg DA. 1989. Inferring mode of inheritance by comparison of lod scores. Am J Med Genet 34: 480-486.[Medline]
7. Haldane JBS. 1919. The combination of linkage values and the calculation of distance between loci of linked factors. J Genet 8: 299-309.
8. Hall JM, Lee MK, Newman B, Morrow JE, Anderson LA, Huey B, King MC. 1990. Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250: 1684-1689.[Abstract/FreeFullText]
9. Hauser L, Boehnke M, Guo S, Risch N. 1996. Affected-sibpair interval mapping and exclusion for complex genetic traits. Genet Epidemiol 13: 117-137.[Medline]
10. Heath SC. 1997. Markov chain Monte Carlo segregation and linkage analysis for oligogenic models. AM J HUM GENET 61: 748-760.[Medline]
11. Holmans P. 1993. Asymptotic properties of affected-sib-pair linkage analysis. AM J HUM GENET 52: 362-374.[Medline]
12. Knapp M, Seuchter SA, Baur MP. 1994. Linkage analysis in nuclear families. 2: Relationship between affected sib-pair tests and lod score analysis. Hum Hered 44: 44-51.[Medline]
13. Kong A, Gudbjartsson DF, Sainz J, Jonsdottir GM, Gudjonsson SA, Richardsson B, Sigurdardottir S, Barnard J, Hallbeck B, Masson G, et al. 2002. A high-resolution recombination map of the human genome. Nat Genet 31: 241-247.[Medline]
14. Kruglyak L, Lander ES. 1995. Complete multipoint sib-pair analysis of qualitative and quantitative traits. AM J HUM GENET 57: 439-454.[Medline]
15. Lander E, Kruglyak L. 1995. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nat Genet 11: 241-247.[Medline]
16. Lange K, Weeks D, Boehnke M. 1988. Programs for pedigree analysis: MENDEL, FISHER, and dGENE. Genet Epidemiol 51: 235-249.
17. Lathrop M, Lalouel JM, Julier C, Ott J. 1984. Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci 81: 3443-3446.[Abstract/FreeFullText]
18. Lewinger JP, Conti DV, Baurley JW, Triche TJ, Thomas DC. 2007. Hierarchical Bayes prioritization of marker associations from a genome-wide association scan for further investigation. Genet Epidemiol 31: 871-882.[Medline]
19. Morton NE. 1955. Sequential tests for the detection of linkage. AM J HUM GENET 7: 277-318.[Medline]
20. O'Connell JR, Weeks DE. 1995. The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-recoding and fuzzy inheritance. Nat Genet 11: 402-408.[Medline]
21. Ott J. 1991. Analysis of human genetic linkage. Johns Hopkins University Press, Baltimore, MD. Rev.
22. Risch N. 1990. Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. AM J HUM GENET 46: 242-253.[Medline]
23. Sobel E, Lange K. 1996. Descent graphs in pedigree analysis: Applications to haplotyping, location scores, and marker sharing statistics. AM J HUM GENET 58: 1323-1337.[Medline]
24. Sobel E, Sengul H, Weeks DE. 2001. Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees. Hum Hered 52: 121-131.[Medline]
25. Sobel E, Papp JC, Lange K. 2002. Detection and integration of genotyping errors in statistical genetics. AM J HUM GENET 70: 496-508.[Medline]
26. Suarez BK, Rice JP, Reich T. 1978. The generalized sib-pair IBD distribution: Its use in the detection of linkage. Ann Hum Genet 42: 87-94.[Medline]
27. Whittemore AS. 1996. Genome scanning for linkage: An overview. AM J HUM GENET 59: 704-716.[Medline]
28. Xu J, Meyers DA, Pericak-Vance MA. 1998. Lod score analysis. In Approaches to gene mapping in complex human diseases (eds. JL Haines and MA Pericak-Vance), pp. 253-272. Wiley, New York.