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Volumn 5, Issue 5, 2010, Pages

Furin targeted drug delivery for treatment of Rhabdomyosarcoma in a mouse model

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; FURIN; MEMBRANE PROTEIN; PROPROTEIN CONVERTASE 7; SERINE PROTEINASE; UNCLASSIFIED DRUG;

EID: 77956287381     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010445     Document Type: Article
Times cited : (30)

References (58)
  • 2
    • 24644440084 scopus 로고    scopus 로고
    • Rhabdomyosarcoma: New windows of opportunity
    • Breitfeld PP, Meyer WH (2005) Rhabdomyosarcoma: new windows of opportunity. Oncologist 10: 518-527.
    • (2005) Oncologist , vol.10 , pp. 518-527
    • Breitfeld, P.P.1    Meyer, W.H.2
  • 3
    • 27144449009 scopus 로고    scopus 로고
    • Monoclonal antibody therapy of cancer
    • Adams GP, Weiner LM (2005) Monoclonal antibody therapy of cancer. Nat Biotechnol 23: 1147-1157.
    • (2005) Nat Biotechnol , vol.23 , pp. 1147-1157
    • Adams, G.P.1    Weiner, L.M.2
  • 4
    • 17144419643 scopus 로고    scopus 로고
    • Therapeutic monoclonal antibodies in oncology
    • Levene AP, Singh G, Palmieri C (2005) Therapeutic monoclonal antibodies in oncology. J R Soc Med 98: 146-152.
    • (2005) J R Soc Med , vol.98 , pp. 146-152
    • Levene, A.P.1    Singh, G.2    Palmieri, C.3
  • 6
    • 15244351004 scopus 로고    scopus 로고
    • Overview of monoclonal antibodies in cancer therapy: Present and promise
    • Stern M, Herrmann R (2005) Overview of monoclonal antibodies in cancer therapy: present and promise. Crit Rev Oncol Hematol 54: 11-29.
    • (2005) Crit Rev Oncol Hematol , vol.54 , pp. 11-29
    • Stern, M.1    Herrmann, R.2
  • 8
    • 34548168881 scopus 로고    scopus 로고
    • Tumour-homing peptides: Tools for targeting, imaging and destruction
    • Enback J, Laakkonen P (2007) Tumour-homing peptides: tools for targeting, imaging and destruction. Biochem Soc Trans 35: 780-783.
    • (2007) Biochem Soc Trans , vol.35 , pp. 780-783
    • Enback, J.1    Laakkonen, P.2
  • 10
    • 3042660212 scopus 로고    scopus 로고
    • Vascular zip codes in angiogenesis and metastasis
    • Ruoslahti E (2004) Vascular zip codes in angiogenesis and metastasis. Biochem Soc Trans 32: 397-402.
    • (2004) Biochem Soc Trans , vol.32 , pp. 397-402
    • Ruoslahti, E.1
  • 11
    • 0141990618 scopus 로고    scopus 로고
    • Mapping tumor vascular diversity by screening phage display libraries
    • Zurita AJ, Arap W, Pasqualini R (2003) Mapping tumor vascular diversity by screening phage display libraries. J Control Release 91: 183-186.
    • (2003) J Control Release , vol.91 , pp. 183-186
    • Zurita, A.J.1    Arap, W.2    Pasqualini, R.3
  • 12
    • 0033993470 scopus 로고    scopus 로고
    • Subtilase-like pro-protein convertases: From molecular specificity to therapeutic applications
    • Bergeron F, Leduc R, Day R (2000) Subtilase-like pro-protein convertases: from molecular specificity to therapeutic applications. J Mol Endocrinol 24: 1-22.
    • (2000) J Mol Endocrinol , vol.24 , pp. 1-22
    • Bergeron, F.1    Leduc, R.2    Day, R.3
  • 13
    • 0033452452 scopus 로고    scopus 로고
    • Proprotein and prohormone convertases: A family of subtilases generating diverse bioactive polypeptides
    • Seidah NG, Chretien M (1999) Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides. Brain Res 848: 45-62.
    • (1999) Brain Res , vol.848 , pp. 45-62
    • Seidah, N.G.1    Chretien, M.2
  • 14
    • 0030725756 scopus 로고    scopus 로고
    • Furin: A mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
    • Nakayama K (1997) Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. Biochem J 327 (Pt3): 625-635.
    • (1997) Biochem J , vol.327 , Issue.PART3 , pp. 625-635
    • Nakayama, K.1
  • 15
    • 0036791359 scopus 로고    scopus 로고
    • Furin at the cutting edge: From protein traffic to embryogenesis and disease
    • Thomas G (2002) Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 3: 753-766.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 753-766
    • Thomas, G.1
  • 16
    • 0036083664 scopus 로고    scopus 로고
    • Proprotein convertases in tumor progression and malignancy: Novel targets in cancer therapy
    • Khatib AM, Siegfried G, Chretien M, Metrakos P, Seidah NG (2002) Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy. Am J Pathol 160: 1921-1935.
    • (2002) Am J Pathol , vol.160 , pp. 1921-1935
    • Khatib, A.M.1    Siegfried, G.2    Chretien, M.3    Metrakos, P.4    Seidah, N.G.5
  • 17
    • 27644521904 scopus 로고    scopus 로고
    • Proprotein convertases: "master switches" in the regulation of tumor growth and progression
    • Bassi DE, Fu J, Lopez de Cicco R, Klein-Szanto AJ (2005) Proprotein convertases: "master switches" in the regulation of tumor growth and progression. Mol Carcinog 44: 151-161.
    • (2005) Mol Carcinog , vol.44 , pp. 151-161
    • Bassi, D.E.1    Fu, J.2    Lopez, C.R.3    Klein-Szanto, A.J.4
  • 18
    • 0034846315 scopus 로고    scopus 로고
    • Elevated furin expression in aggressive human head and neck tumors and tumor cell lines
    • Bassi DE, Mahloogi H, Al-Saleem L, Lopez De Cicco R, Ridge JA, et al. (2001) Elevated furin expression in aggressive human head and neck tumors and tumor cell lines. Mol Carcinog 31: 224-232.
    • (2001) Mol Carcinog , vol.31 , pp. 224-232
    • Bassi, D.E.1    Mahloogi, H.2    Al-Saleem, L.3    Lopez, C.R.4    Ridge, J.A.5
  • 19
    • 0038481179 scopus 로고    scopus 로고
    • The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis
    • Siegfried G, Basak A, Cromlish JA, Benjannet S, Marcinkiewicz J, et al. (2003) The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. J Clin Invest 111: 1723-1732.
    • (2003) J Clin Invest , vol.111 , pp. 1723-1732
    • Siegfried, G.1    Basak, A.2    Cromlish, J.A.3    Benjannet, S.4    Marcinkiewicz, J.5
  • 20
    • 33947670424 scopus 로고    scopus 로고
    • Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2
    • McColl BK, Paavonen K, Karnezis T, Harris NC, Davydova N, et al. (2007) Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2. Faseb J 21: 1088-1098.
    • (2007) Faseb J , vol.21 , pp. 1088-1098
    • McColl, B.K.1    Paavonen, K.2    Karnezis, T.3    Harris, N.C.4    Davydova, N.5
  • 21
    • 0035141634 scopus 로고    scopus 로고
    • Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme
    • Dubois CM, Blanchette F, Laprise MH, Leduc R, Grondin F, et al. (2001) Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme. Am J Pathol 158: 305-316.
    • (2001) Am J Pathol , vol.158 , pp. 305-316
    • Dubois, C.M.1    Blanchette, F.2    Laprise, M.H.3    Leduc, R.4    Grondin, F.5
  • 22
    • 0035903230 scopus 로고    scopus 로고
    • Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: Importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions
    • Khatib AM, Siegfried G, Prat A, Luis J, Chretien M, et al. (2001) Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions. J Biol Chem 276: 30686-30693.
    • (2001) J Biol Chem , vol.276 , pp. 30686-30693
    • Khatib, A.M.1    Siegfried, G.2    Prat, A.3    Luis, J.4    Chretien, M.5
  • 24
    • 4344645902 scopus 로고    scopus 로고
    • Proprotein convertases regulate insulin-like growth factor 1-induced membranetype 1 matrix metalloproteinase in VSMCs via endoproteolytic activation of the insulin-like growth factor-1 receptor
    • Stawowy P, Kallisch H, Kilimnik A, Margeta C, Seidah NG, et al. (2004) Proprotein convertases regulate insulin-like growth factor 1-induced membranetype 1 matrix metalloproteinase in VSMCs via endoproteolytic activation of the insulin-like growth factor-1 receptor. Biochem Biophys Res Commun 321: 531-538.
    • (2004) Biochem Biophys Res Commun , vol.321 , pp. 531-538
    • Stawowy, P.1    Kallisch, H.2    Kilimnik, A.3    Margeta, C.4    Seidah, N.G.5
  • 25
    • 0242710747 scopus 로고    scopus 로고
    • TACE/ ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity
    • Srour N, Lebel A, McMahon S, Fournier I, Fugere M, et al. (2003) TACE/ ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity. FEBS Lett 554: 275-283.
    • (2003) FEBS Lett , vol.554 , pp. 275-283
    • Srour, N.1    Lebel, A.2    McMahon, S.3    Fournier, I.4    Fugere, M.5
  • 26
    • 0041344533 scopus 로고    scopus 로고
    • Processing of alpha4 integrin by the proprotein convertases: Histidine at position P6 regulates cleavage
    • Bergeron E, Basak A, Decroly E, Seidah NG (2003) Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage. Biochem J 373: 475-484.
    • (2003) Biochem J , vol.373 , pp. 475-484
    • Bergeron, E.1    Basak, A.2    Decroly, E.3    Seidah, N.G.4
  • 27
    • 52049103578 scopus 로고    scopus 로고
    • Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like proprotein convertases
    • Varshavsky A, Kessler O, Abramovitch S, Kigel B, Zaffryar S, et al. (2008) Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like proprotein convertases. Cancer Res 68: 6922-6931.
    • (2008) Cancer Res , vol.68 , pp. 6922-6931
    • Varshavsky, A.1    Kessler, O.2    Abramovitch, S.3    Kigel, B.4    Zaffryar, S.5
  • 28
    • 38149024974 scopus 로고    scopus 로고
    • Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells
    • Scamuffa N, Siegfried G, Bontemps Y, Ma L, Basak A, et al. (2008) Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells. The Journal of clinical investigation 118: 352-363.
    • (2008) The Journal of clinical investigation , vol.118 , pp. 352-363
    • Scamuffa, N.1    Siegfried, G.2    Bontemps, Y.3    Ma, L.4    Basak, A.5
  • 29
    • 19544393760 scopus 로고    scopus 로고
    • Cutting back on pro-protein convertases: The latest approaches to pharmacological inhibition
    • Fugere M, Day R (2005) Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition. Trends Pharmacol Sci 26: 294-301.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 294-301
    • Fugere, M.1    Day, R.2
  • 30
    • 0035964398 scopus 로고    scopus 로고
    • Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells
    • Bassi DE, Lopez De Cicco R, Mahloogi H, Zucker S, Thomas G, et al. (2001) Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells. Proc Natl Acad Sci USA 98: 10326-10331.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10326-10331
    • Bassi, D.E.1    Lopez, C.R.2    Mahloogi, H.3    Zucker, S.4    Thomas, G.5
  • 31
    • 35148878210 scopus 로고    scopus 로고
    • Opposing Function of the Proprotein Convertases Furin and PACE4 on Breast Cancer Cells' Malignant Phenotypes: Role of Tissue Inhibitors of Metalloproteinase-1
    • Lapierre M, Siegfried G, Scamuffa N, Bontemps Y, Calvo F, et al. (2007) Opposing Function of the Proprotein Convertases Furin and PACE4 on Breast Cancer Cells' Malignant Phenotypes: Role of Tissue Inhibitors of Metalloproteinase-1. Cancer Research 67: 9030-9034.
    • (2007) Cancer Research , vol.67 , pp. 9030-9034
    • Lapierre, M.1    Siegfried, G.2    Scamuffa, N.3    Bontemps, Y.4    Calvo, F.5
  • 32
    • 70350270028 scopus 로고    scopus 로고
    • The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: In vivo mouse model
    • Sun X, Essalmani R, Seidah NG, Prat A (2009) The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model. Mol Cancer 8: 73.
    • (2009) Mol Cancer , vol.8 , pp. 73
    • Sun, X.1    Essalmani, R.2    Seidah, N.G.3    Prat, A.4
  • 34
    • 63449097054 scopus 로고    scopus 로고
    • Identification of a rhabdomyosarcoma targeting peptide by phage display with sequence similarities to the tumour lymphatic-homing peptide LyP-1
    • Witt H, Hajdin K, Iljin K, Greiner O, Niggli FK, et al. (2009) Identification of a rhabdomyosarcoma targeting peptide by phage display with sequence similarities to the tumour lymphatic-homing peptide LyP-1. Int J Cancer 124: 2026-2032.
    • (2009) Int J Cancer , vol.124 , pp. 2026-2032
    • Witt, H.1    Hajdin, K.2    Iljin, K.3    Greiner, O.4    Niggli, F.K.5
  • 35
    • 0030909584 scopus 로고    scopus 로고
    • Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours
    • Mbikay M, Sirois F, Yao J, Seidah NG, Chretien M (1997) Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours. Br J Cancer 75: 1509-1514.
    • (1997) Br J Cancer , vol.75 , pp. 1509-1514
    • Mbikay, M.1    Sirois, F.2    Yao, J.3    Seidah, N.G.4    Chretien, M.5
  • 36
    • 0027337146 scopus 로고
    • Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin
    • Komada M, Hatsuzawa K, Shibamoto S, Ito F, Nakayama K, et al. (1993) Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin. FEBS Lett 328: 25-29.
    • (1993) FEBS Lett , vol.328 , pp. 25-29
    • Komada, M.1    Hatsuzawa, K.2    Shibamoto, S.3    Ito, F.4    Nakayama, K.5
  • 37
    • 0028815633 scopus 로고
    • A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation
    • Takahashi S, Nakagawa T, Kasai K, Banno T, Duguay SJ, et al. (1995) A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation. J Biol Chem 270: 26565-26569.
    • (1995) J Biol Chem , vol.270 , pp. 26565-26569
    • Takahashi, S.1    Nakagawa, T.2    Kasai, K.3    Banno, T.4    Duguay, S.J.5
  • 38
    • 0032560449 scopus 로고    scopus 로고
    • alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: Application as an antipathogenic agent
    • Jean F, Stella K, Thomas L, Liu G, Xiang Y, et al. (1998) alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent. Proc Natl Acad Sci USA 95: 7293-7298.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7293-7298
    • Jean, F.1    Stella, K.2    Thomas, L.3    Liu, G.4    Xiang, Y.5
  • 39
    • 0036063778 scopus 로고    scopus 로고
    • A tumor-homing peptide with a targeting specificity related to lymphatic vessels
    • Laakkonen P, Porkka K, Hoffman JA, Ruoslahti E (2002) A tumor-homing peptide with a targeting specificity related to lymphatic vessels. Nat Med 8: 751-755.
    • (2002) Nat Med , vol.8 , pp. 751-755
    • Laakkonen, P.1    Porkka, K.2    Hoffman, J.A.3    Ruoslahti, E.4
  • 40
    • 0344185348 scopus 로고    scopus 로고
    • Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis
    • Joyce JA, Laakkonen P, Bernasconi M, Bergers G, Ruoslahti E, et al. (2003) Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 4: 393-403.
    • (2003) Cancer Cell , vol.4 , pp. 393-403
    • Joyce, J.A.1    Laakkonen, P.2    Bernasconi, M.3    Bergers, G.4    Ruoslahti, E.5
  • 41
    • 70349482671 scopus 로고    scopus 로고
    • C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
    • Teesalu T, Sugahara KN, Kotamraju VR, Ruoslahti E (2009) C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration. Proc Natl Acad Sci USA 106: 16157-16162.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16157-16162
    • Teesalu, T.1    Sugahara, K.N.2    Kotamraju, V.R.3    Ruoslahti, E.4
  • 43
    • 33646236541 scopus 로고    scopus 로고
    • Oligoarginine vectors for intracellular delivery: Design and cellular-uptake mechanisms
    • Futaki S (2006) Oligoarginine vectors for intracellular delivery: design and cellular-uptake mechanisms. Biopolymers 84: 241-249.
    • (2006) Biopolymers , vol.84 , pp. 241-249
    • Futaki, S.1
  • 45
    • 0029836967 scopus 로고    scopus 로고
    • Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines
    • Decroly E, Wouters S, Di Bello C, Lazure C, Ruysschaert JM, et al. (1996) Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines. J Biol Chem 271: 30442-30450.
    • (1996) J Biol Chem , vol.271 , pp. 30442-30450
    • Decroly, E.1    Wouters, S.2    Di Bello, C.3    Lazure, C.4    Ruysschaert, J.M.5
  • 46
    • 0027438237 scopus 로고
    • Processing protease for gp160 human immunodeficiency virus type I envelope glycoprotein precursor in human T4+ lymphocytes. Purification and characterization
    • Kido H, Kamoshita K, Fukutomi A, Katunuma N (1993) Processing protease for gp160 human immunodeficiency virus type I envelope glycoprotein precursor in human T4+ lymphocytes. Purification and characterization. J Biol Chem 268: 13406-13413.
    • (1993) J Biol Chem , vol.268 , pp. 13406-13413
    • Kido, H.1    Kamoshita, K.2    Fukutomi, A.3    Katunuma, N.4
  • 47
    • 0037111737 scopus 로고    scopus 로고
    • Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: Involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates
    • Laprise MH, Grondin F, Cayer P, McDonald PP, Dubois CM (2002) Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates. Blood 100: 3578-3587.
    • (2002) Blood , vol.100 , pp. 3578-3587
    • Laprise, M.H.1    Grondin, F.2    Cayer, P.3    McDonald, P.P.4    Dubois, C.M.5
  • 48
    • 0036278838 scopus 로고    scopus 로고
    • Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasiveness
    • Mercapide J, Lopez De Cicco R, Bassi DE, Castresana JS, Thomas G, et al. (2002) Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasiveness. Clin Cancer Res 8: 1740-1746.
    • (2002) Clin Cancer Res , vol.8 , pp. 1740-1746
    • Mercapide, J.1    Lopez, C.R.2    Bassi, D.E.3    Castresana, J.S.4    Thomas, G.5
  • 49
    • 10644284710 scopus 로고    scopus 로고
    • BCL-2-induced glioma cell invasiveness depends on furin-like proteases
    • Wick W, Wild-Bode C, Frank B, Weller M (2004) BCL-2-induced glioma cell invasiveness depends on furin-like proteases. J Neurochem 91: 1275-1283.
    • (2004) J Neurochem , vol.91 , pp. 1275-1283
    • Wick, W.1    Wild-Bode, C.2    Frank, B.3    Weller, M.4
  • 50
    • 2942529235 scopus 로고    scopus 로고
    • Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy
    • Oh P, Li Y, Yu J, Durr E, Krasinska KM, et al. (2004) Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy. Nature 429: 629-635.
    • (2004) Nature , vol.429 , pp. 629-635
    • Oh, P.1    Li, Y.2    Yu, J.3    Durr, E.4    Krasinska, K.M.5
  • 51
    • 52049123781 scopus 로고    scopus 로고
    • Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma
    • Fogal V, Zhang L, Krajewski S, Ruoslahti E (2008) Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma. Cancer Res 68: 7210-7218.
    • (2008) Cancer Res , vol.68 , pp. 7210-7218
    • Fogal, V.1    Zhang, L.2    Krajewski, S.3    Ruoslahti, E.4
  • 52
    • 0344304541 scopus 로고    scopus 로고
    • Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels
    • Christian S, Pilch J, Akerman ME, Porkka K, Laakkonen P, et al. (2003) Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels. J Cell Biol 163: 871-878.
    • (2003) J Cell Biol , vol.163 , pp. 871-878
    • Christian, S.1    Pilch, J.2    Akerman, M.E.3    Porkka, K.4    Laakkonen, P.5
  • 53
    • 77951248592 scopus 로고    scopus 로고
    • A novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C
    • Basak A, Khatib AM, Mohottalage D, Basak S, Kolajova M, et al. (2009) A novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C. PLoS One 4: e7700.
    • (2009) PLoS One , vol.4
    • Basak, A.1    Khatib, A.M.2    Mohottalage, D.3    Basak, S.4    Kolajova, M.5
  • 55
    • 0342698808 scopus 로고    scopus 로고
    • Molecular features of a human rhabdomyosarcoma cell line with spontaneous metastatic progression
    • Scholl FA, Betts DR, Niggli FK, Schafer BW (2000) Molecular features of a human rhabdomyosarcoma cell line with spontaneous metastatic progression. Br J Cancer 82: 1239-1245.
    • (2000) Br J Cancer , vol.82 , pp. 1239-1245
    • Scholl, F.A.1    Betts, D.R.2    Niggli, F.K.3    Schafer, B.W.4
  • 56
    • 0037332088 scopus 로고    scopus 로고
    • Increased furin activity enhances the malignant phenotype of human head and neck cancer cells
    • Bassi DE, Mahloogi H, Lopez De Cicco R, Klein-Szanto A (2003) Increased furin activity enhances the malignant phenotype of human head and neck cancer cells. Am J Pathol 162: 439-447.
    • (2003) Am J Pathol , vol.162 , pp. 439-447
    • Bassi, D.E.1    Mahloogi, H.2    Lopez, C.R.3    Klein-Szanto, A.4
  • 57
    • 33745271924 scopus 로고    scopus 로고
    • In vivo and ex vivo selections using phage-displayed libraries
    • In: Clarkson T, Lowman H, eds. Oxford, U.K: Oxford University Press
    • Hoffman JA, Laakkonen P, Porkka K, Bernasconi M, Ruoslahti E (2004) In vivo and ex vivo selections using phage-displayed libraries. In: Clarkson T, Lowman H, eds. Phage Display: A Practical Approach. Oxford, U.K: Oxford University Press. pp 169-186.
    • (2004) Phage Display: A Practical Approach , pp. 169-186
    • Hoffman, J.A.1    Laakkonen, P.2    Porkka, K.3    Bernasconi, M.4    Ruoslahti, E.5
  • 58
    • 4143150844 scopus 로고    scopus 로고
    • Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1
    • Wachtel M, Dettling M, Koscielniak E, Stegmaier S, Treuner J, et al. (2004) Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1. Cancer Res 64: 5539-5545.
    • (2004) Cancer Res , vol.64 , pp. 5539-5545
    • Wachtel, M.1    Dettling, M.2    Koscielniak, E.3    Stegmaier, S.4    Treuner, J.5


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