MUT-TP53 2.0: A novel versatile matrix for statistical analysis of TP53 mutations in human cancer

Human Mutation

Volumn 31, Issue 9, 2010, Pages 1020-1025

  Soussi, Thierry ^a,b   Hamroun, Dalil ^c   Hjortsberg, Linn ^a   Rubio Nevado, Jean Michel ^b   Fournier, Jean Louis ^b   Béroud, Christophe ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIV MONTPELLIER   (France)

^c INSTITUTE OF HUMAN GENETICS   (France)

Author keywords

Cancer; Curation; Database; TP53; Tumor

Indexed keywords

PROTEIN P53;

ARTICLE; BIOLOGICAL ACTIVITY; COMPUTER PROGRAM; DIAGNOSTIC ACCURACY; ERROR; GENE MUTATION; LOSS OF FUNCTION MUTATION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; HUMANS; META-ANALYSIS AS TOPIC; MUTANT PROTEINS; MUTATION; NEOPLASMS; SOFTWARE; STATISTICS AS TOPIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77956282429     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21313     Document Type: Article

References (20)

1. Brash DE. 1997. Sunlight and the onset of skin cancer. Trends Genet 13:410-414.
2. Campbell IG, Qiu W, Polyak K, Haviv I. 2008. Breast-cancer stromal cells with TP53 mutations. N Engl J Med 358:1634-1635; author reply 1636.
3. Chanock SJ, Thomas G. 2007. The devil is in the DNA. Nat Genet 39:283-284.
4. den Dunnen JT, Antonarakis SE. 2000. Mutation nomenclature extensions and suggestions to describe complex mutations: a discussion. Hum Mutat 15:7-12.
5. DiGiammarino EL, Lee AS, Cadwell C, Zhang W, Bothner B, Ribeiro RC, Zambetti G, Kriwacki RW. 2002. A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer. Nat Struct Biol 9:12-16. (Pubitemid 34049172)
6. Horaitis O, Cotton RG. 2004. The challenge of documenting mutation across the genome: the human genome variation society approach. Hum Mutat 23:447-452. (Pubitemid 38569217)
7. Kato S, Han SY, Liu W, Otsuka K, Shibata H, Kanamaru R, Ishioka C. 2003. Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. Proc Natl Acad Sci USA 100:8424-8429. (Pubitemid 36842561)
8. Ng PC, Henikoff S. 2001. Predicting deleterious amino acid substitutions. Genome Res 11:863-874. (Pubitemid 32447869)
9. Resnick MA, Inga A. 2003. Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity. Proc Natl Acad Sci USA 100:9934-9939. (Pubitemid 37087046)
10. Ribeiro RC, Sandrini F, Figueiredo B, Zambetti GP, Michalkiewicz E, Lafferty AR, DeLacerda L, Rabin M, Cadwell C, Sampaio G, Cat I, Stratakis CA, Sandrini R. 2001. An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma. Proc Natl Acad Sci USA 98:9330-9335.
11. Roukos DH. 2008. Breast-cancer stromal cells with TP53 mutations. N Engl J Med 358:1636; author reply 1636.
12. Soussi T, Asselain B, Hamroun D, Kato S, Ishioka C, Claustres M, Beroud C. 2006. Meta-analysis of the p53 mutation database for mutant p53 biological activity reveals a methodologic bias in mutation detection. Clin Cancer Res 12: 62-69. (Pubitemid 43166177)
13. Soussi T, Kato S, Levy PP, Ishioka C. 2005. Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations. Hum Mutat 25:6-17. (Pubitemid 40075908)
14. Soussi T, Lozano G. 2005. p53 mutation heterogeneity in cancer. Biochem Biophys Res Commun 331:834-842.
15. Soussi T, Rubio-Nevado JM, Ishioka C. 2006. MUT-TP53: a versatile matrix for TP53 mutation verification and publication. Hum Mutat 27:1151-1154. (Pubitemid 44730511)
16. Soussi-Zander C, Soussi T. 2008. Breast-cancer stromal cells with TP53 mutations. N Engl J Med 358:1635; author reply 1636. (Pubitemid 351519838)
17. Stratton MR, Campbell PJ, Futreal PA. 2009. The cancer genome. Nature 458:719-724.
18. Strausberg RL, Simpson AJ. 2010. Whole-genome cancer analysis as an approach to deeper understanding of tumour biology. Br J Cancer 102:243-248.
19. Varley JM, Attwooll C, White G, McGown G, Thorncroft M, Kelsey AM, Greaves M, Boyle J, Birch JM. 2001. Characterization of germline TP53 splicing mutations and their genetic and functional analysis. Oncogene 20:2647-2654. (Pubitemid 32525295)
20. Zalcman G, Bergot E, Hainaut P. 2008. Breast-cancer stromal cells with TP53 mutations. N Engl J Med 358:1635-1636; author reply 1636.