Anthrax toxin-neutralizing antibody reconfigures the protective antigen heptamer into a supercomplex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 32, 2010, Pages 14070-14074

  Radjainia, Mazdak ^a   Hyun, Jae Kyung ^a   Leysath, Clinton E ^b   Leppla, Stephen H ^b   Mitra, Alok K ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Anthrax toxin; Neutralizing antibody 1G3; Passive immunization; Protein therapeutics; Single particle analysis

Indexed keywords

ANTHRAX TOXIN; ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1G3; PROTECTIVE ANTIGEN HEPTAMER; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIAL TOXIN; NEUTRALIZING ANTIBODY;

ARTICLE; ELECTRON MICROSCOPY; LETHAL GENE; PHENOTYPE; PRIORITY JOURNAL; ANIMAL; ANTIGEN ANTIBODY COMPLEX; CHEMISTRY; HUMAN; IMMUNOLOGY; MOUSE; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; HUMANS; MICE; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION;

BACILLUS ANTHRACIS;

EID: 77956277077     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1006473107     Document Type: Article

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