Autonomous magnetically actuated continuous flow microimmunofluorocytometry assay

Microfluidics and Nanofluidics

Volumn 9, Issue 2-3, 2010, Pages 253-265

  Sasso, Lawrence A ^a   Ündar, Akif ^b   Zahn, Jeffrey D ^a  

^a RUTGERS UNIVERSITY   (United States)

^b PENN STATE CHILDREN S HOSPITAL   (United States)

Author keywords

Biosensor; Fluorocytometry; Immunoassay; Magnetic actuation

Indexed keywords

ANAPHYLATOXIN; BINDING REACTIONS; CARDIAC SURGERY; CARDIOPULMONARY BYPASS; CLINICAL APPLICATION; CONTINUOUS FLOWS; DEVICE OPERATIONS; EXTERNAL CONTROL; FLUORESCENCE DETECTION; FLUOROCYTOMETRY; IMMUNOASSAY; INTEGRATED FLUORESCENCE DETECTION; MAGNETIC ACTUATION; MARKER PROTEINS; MICRO DEVICES; MICRO-FLUIDIC DEVICES; MICROBEADS; PROTEIN CONCENTRATIONS; SAMPLE RATE; SAMPLE VOLUME; SANDWICH IMMUNOASSAY; SERIAL PROCESSING; STREPTAVIDIN; SYSTEMIC INFLAMMATION; TIME VARYING;

ANTIGENS; BIOSENSORS; CARDIOVASCULAR SURGERY; FLUORESCENCE; IMMUNOLOGY; PARAMAGNETIC MATERIALS; PATHOLOGY; PROTEINS;

BIOASSAY;

EID: 77956268742     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-009-0543-1     Document Type: Article

References (27)

1. Ahn KC, Lohstroh P, Gee SJ, Gee NA, Lasley B, Hammock BD (2007) High-throughput automated luminescent magnetic particle- based immunoassay to monitor human exposure to pyrethroid insecticides. Anal Chem 79:8883-8890
2. Aoyagi S, Miyasaka T, Yoshimi Y, Sakai K (2002) A new reagentless immunosensor for measuring IgG concentration in human plasma based on fluorescence-enhancement immunoassay. Japn Soc Artif Organs 5:60-63
3. Ascione R, Lloyd CT, Underwood MJ, Lotto AA, Pitsis AA, Angelini GD (2000) Inflammatory response after coronary revascularization with or without cardiopulmonary bypass. Ann Thorac Surg 69:1198-1204 (Pubitemid 30259386)
4. Barton AC, Davis F, Higson SPJ (2008) Labeless immunosensor assay for prostate specific antigen with picogram per milliliter limits of detection based upon an ac impedance protocol. Anal Chem 80:6198-6205
5. BD Biosciences (2007) BD Cytometric Bead Array (CBA), Human Anaphylatoxin Kit instruction manual
6. Bhattacharyya A, Klapperich CM (2007) Design and testing of a disposable microfluidic chemiluminescent immunoassay for disease biomarkers in human serum samples. Biomed Microdevices 9:245-251
7. Cheng XH, Irimia D, Dixon M, Sekine K, Demirci U, Zamir L, Tompkins RG, Rodriguez W, Toner M (2007) A microfluidic device for practical label-free CD4? T cell counting of HIVinfected subjects. Lab Chip 7:170-178
8. Choi JW, Oh KW, Thomas JH, Heineman WR, Halsall HB, Nevin JH, Helmicki AJ, Henderson HT, Ahn CH (2002) An integrated microfluidic biochemical detection system for protein analysis with magnetic bead-based sampling capabilities. Lab Chip 2:27-30
9. Do J, Ahn CH (2008) A polymer lab-on-a-chip for magnetic immunoassay with on-chip sampling and detection capabilities. Lab Chip 8:542-549
10. Duffy DC, McDonald JC, Schueller OJA, Whitesides GM (1998) Rapid prototyping of microfluidic systems in poly(dimethylsiloxane). Anal Chem 70:4974-4984
11. Engstrom HA, Andersson PO, Ohlson S (2006) A label-free continuous total-internal-reflection-fluorescence-based immunosensor. Anal Biochem 357:159-166
12. Fung M, Loubser PG, Undar A, Mueller M, Sun C, Sun WN, Vaughn WK, Fraser CD (2001) Inhibition of complement neutrophil, and platelet activation by an anti-factor D monoclonal antibody insimulated cardiopulmonary bypass circuits. J Thorac Cardiovasc Surg 122:113-122
13. Herrmann M, Veres T, Tabrizian M (2006) Enzymatically-generated fluorescent detection in micro-channels with internal magnetic mixing for the development of parallel microfluidic ELISA. Lab Chip 6:555-560
14. Kartalov EP, Zhong JF, Scherer A, Quake SR, Taylor CR, Anderson WF (2006) High-throughput multi-antigen microfluidic fluorescence immunoassays. Biotechniques 40:85-90
15. Kim KS, Park JK (2005) Magnetic force-based multiplexed immunoassay using superparamagnetic nanoparticles in microfluidic channel. Lab Chip 5:657-664
16. Kirklin JW, Barratt-Boyes BG (1993) Hypothermia, circulatory arrest, and cardiopulmonary bypass. In: Kirklin JW, Barratt- Boyes BG (eds) Cardiac surgery. New York: Churchill Livingstone
17. Mainwaring RD, Lamberti JJ, Hugli TE (1998) Complement activation and cytokine generation after modified Fontan procedure. Ann Thorac Surg 65:1715-1720
18. Moore FD, Warner KG, Assousa S (1988) The effects of complement activation during cardiopulmonary bypass: attenuation by hypothermia, heparin, and hemodilution. Ann Surg 208:95-103
19. Pamme N (2006) Magnetism and microfluidics. Lab Chip 6:24-38
20. Peyman SA, Iles A, Pamme N (2008) Rapid on-chip multi-step (bio)chemical procedures in continuous flow-manoeuvring particles through co-laminar reagent streams. Chem Commun 1220-1222
21. Roper MG, Shackman JG, Dahlgren GM, Kennedy RT (2003) Microfluidic chip for continuous monitoring of hormone secretion from live cells using an electrophoresis-based immunoassay. Anal Chem 75:4711-4717
22. Sato K, Yamanaka M, Hagino T, Tokeshi M, Kimura H, Kitamori T (2004) Microchip-based enzyme-linked immunosorbent assay (microELISA) system with thermal lens detection. Lab Chip 4:570-575
23. Shevkoplyas SS, Siegel AC, Westervelt RM, Prentiss MG, Whitesides GM (2007) The force acting on a superparamagnetic bead due to an applied magnetic field. Lab Chip 7:1294-1302
24. Wang HX, Meng S, Guo K, Liu Y, Yang PY, Zhong W, Liu BH (2008) Microfluidic immunosensor based on stable antibodypatterned surface in PMMA microchip. Electrochem Commun 10:447-450
25. Westaby S (1987) Organ dysfunction after cardiopulmonary bypass: a systemic inflammatory reaction initiated by the extracorporeal circuit. Intensive Care Med 13:89-95
26. Xia YN, Whitesides GM (1998) Soft lithography. Annu Rev Mater Sci 28:153-184
27. Yang S, Undar A, Zahn JD (2007) Continuous cytometric bead processing within a microfluidic device for bead based sensing platforms. Lab Chip 7:588-595