FastTrack to supercritical fluid chromatographic purification: Implementation of a walk-up analytical supercritical fluid chromatography/mass spectrometry screening system in the medicinal chemistry laboratory

Journal of Chromatography A

Volumn 1217, Issue 39, 2010, Pages 6110-6114

  Aurigemma, Christine ^a   Farrell, William ^a  

^a PFIZER INC   (United States)

Author keywords

Analytical SFC; Open access SFC; Supercritical fluid chromatography; Walk up screening

Indexed keywords

ANALYTICAL INSTRUMENTATION; ANALYTICAL SFC; BIOLOGICAL ASSAYS; CHROMATOGRAPHIC PURIFICATION; CHROMATOGRAPHIC SEPARATIONS; CHROMATOGRAPHY/MASS SPECTROMETRY; FREE BASE; MEDICINAL CHEMISTRY; OPEN ACCESS; PHARMACEUTICAL DISCOVERY; PURE COMPOUNDS; PURIFICATION PROCESS; REACTION MONITORING; SCREENING METHODS; SCREENING SYSTEM; SIDE PRODUCTS; SUPERCRITICAL FLUID CHROMATOGRAPHY; WALK-UP SCREENING;

CHEMICAL LABORATORIES; DATA PROCESSING; EFFLUENT TREATMENT; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PURIFICATION; SUPERCRITICAL FLUIDS;

CHEMICAL ANALYSIS;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; MASS SPECTROMETRY; PRIORITY JOURNAL; PROCESS DESIGN; PROCESS TECHNOLOGY; PURIFICATION; REACTION TIME; SEPARATION TECHNIQUE; SUPERCRITICAL FLUID CHROMATOGRAPHY; SYSTEM ANALYSIS;

CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, SUPERCRITICAL FLUID; MASS SPECTROMETRY;

EID: 77956268427     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.07.066     Document Type: Article

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