-
1
-
-
41949096891
-
Oncolytic virotherapy: Molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic viruses
-
Guo, ZS, Thorne, SH and Bartlett, DL (2008). Oncolytic virotherapy: molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic viruses. Biochim Biophys Acta 1785: 217-231.
-
(2008)
Biochim Biophys Acta
, vol.1785
, pp. 217-231
-
-
Guo, Z.S.1
Thorne, S.H.2
Bartlett, D.L.3
-
2
-
-
57749201655
-
Targeted and armed oncolytic poxviruses: A novel multi-mechanistic therapeutic class for cancer
-
Kirn, DH and Thorne, SH (2009). Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer. Nat Rev Cancer 9: 64-71.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 64-71
-
-
Kirn, D.H.1
Thorne, S.H.2
-
3
-
-
44249100151
-
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: A phase i trial
-
Park, BH, Hwang, T, Liu, TC, Sze, DY, Kim, JS, Kwon, HC et al. (2008). Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial. Lancet Oncol 9: 533-542.
-
(2008)
Lancet Oncol
, vol.9
, pp. 533-542
-
-
Park, B.H.1
Hwang, T.2
Liu, T.C.3
Sze, D.Y.4
Kim, J.S.5
Kwon, H.C.6
-
4
-
-
44349106062
-
Translation of targeted oncolytic virotherapeutics from the lab into the clinic, and back again: A high-value iterative loop
-
Liu, TC, Hwang, TH, Bell, JC and Kirn, DH (2008). Translation of targeted oncolytic virotherapeutics from the lab into the clinic, and back again: a high-value iterative loop. Mol Ther 16: 1006-1008.
-
(2008)
Mol Ther
, vol.16
, pp. 1006-1008
-
-
Liu, T.C.1
Hwang, T.H.2
Bell, J.C.3
Kirn, D.H.4
-
5
-
-
33846650370
-
Clinical trial results with oncolytic virotherapy: A century of promise, a decade of progress
-
Liu, TC, Galanis, E and Kirn, D (2007). Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress. Nat Clin Pract Oncol 4: 101-117.
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 101-117
-
-
Liu, T.C.1
Galanis, E.2
Kirn, D.3
-
6
-
-
33845336115
-
A phase i study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor
-
Hu, JC, Coffin, RS, Davis, CJ, Graham, NJ, Groves, N, Guest, PJ et al. (2006). A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res 12: 6737-6747.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6737-6747
-
-
Hu, J.C.1
Coffin, R.S.2
Davis, C.J.3
Graham, N.J.4
Groves, N.5
Guest, P.J.6
-
7
-
-
33847378044
-
Phase 1 clinical experience using intravenous administration of PV701, an oncolytic Newcastle disease virus
-
Lorence, RM, Roberts, MS, ONeil, JD, Groene, WS, Miller, JA, Mueller, SN et al. (2007). Phase 1 clinical experience using intravenous administration of PV701, an oncolytic Newcastle disease virus. Curr Cancer Drug Targets 7: 157-167.
-
(2007)
Curr Cancer Drug Targets
, vol.7
, pp. 157-167
-
-
Lorence, R.M.1
Roberts, M.S.2
Oneil, J.D.3
Groene, W.S.4
Miller, J.A.5
Mueller, S.N.6
-
8
-
-
49249131785
-
Virus combinations and chemotherapy for the treatment of human cancers
-
Kumar, S, Gao, L, Yeagy, B and Reid, T (2008). Virus combinations and chemotherapy for the treatment of human cancers. Curr Opin Mol Ther 10: 371-379.
-
(2008)
Curr Opin Mol Ther
, vol.10
, pp. 371-379
-
-
Kumar, S.1
Gao, L.2
Yeagy, B.3
Reid, T.4
-
9
-
-
68249122152
-
Treatment with cyclooxygenase-2 inhibitors enables repeated administration of vaccinia virus for control of ovarian cancer
-
Chang, CL, Ma, B, Pang, X, Wu, TC and Hung, CF (2009). Treatment with cyclooxygenase-2 inhibitors enables repeated administration of vaccinia virus for control of ovarian cancer. Mol Ther 17: 1365-1372.
-
(2009)
Mol Ther
, vol.17
, pp. 1365-1372
-
-
Chang, C.L.1
Ma, B.2
Pang, X.3
Wu, T.C.4
Hung, C.F.5
-
10
-
-
33748088164
-
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses
-
Fulci, G, Breymann, L, Gianni, D, Kurozomi, K, Rhee, SS, Yu, J et al. (2006). Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proc Natl Acad Sci USA 103: 12873-12878.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12873-12878
-
-
Fulci, G.1
Breymann, L.2
Gianni, D.3
Kurozomi, K.4
Rhee, S.S.5
Yu, J.6
-
11
-
-
65249177789
-
Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide
-
Lun, XQ, Jang, JH, Tang, N, Deng, H, Head, R, Bell, JC et al. (2009). Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide. Clin Cancer Res 15: 2777-2788.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2777-2788
-
-
Lun, X.Q.1
Jang, J.H.2
Tang, N.3
Deng, H.4
Head, R.5
Bell, J.C.6
-
12
-
-
42049121876
-
Enhancing poxvirus oncolytic effects through increased spread and immune evasion
-
Kirn, DH, Wang, Y, Liang, W, Contag, CH and Thorne, SH (2008). Enhancing poxvirus oncolytic effects through increased spread and immune evasion. Cancer Res 68: 2071-2075.
-
(2008)
Cancer Res
, vol.68
, pp. 2071-2075
-
-
Kirn, D.H.1
Wang, Y.2
Liang, W.3
Contag, C.H.4
Thorne, S.H.5
-
13
-
-
38049051428
-
Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy
-
Qiao, J, Kottke, T, Willmon, C, Galivo, F, Wongthida, P, Diaz, RM et al. (2008). Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy. Nat Med 14: 37-44.
-
(2008)
Nat Med
, vol.14
, pp. 37-44
-
-
Qiao, J.1
Kottke, T.2
Willmon, C.3
Galivo, F.4
Wongthida, P.5
Diaz, R.M.6
-
14
-
-
49649090374
-
Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma
-
Gulley, JL, Arlen, PM, Tsang, KY, Yokokawa, J, Palena, C, Poole, DJ et al. (2008). Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma. Clin Cancer Res 14: 3060-3069.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3060-3069
-
-
Gulley, J.L.1
Arlen, P.M.2
Tsang, K.Y.3
Yokokawa, J.4
Palena, C.5
Poole, D.J.6
-
16
-
-
68549110430
-
Immune evasion mechanisms in colorectal cancer liver metastasis patients vaccinated with TroVax (MVA-5T4
-
Elkord, E, Dangoor, A, Burt, DJ, Southgate, TD, Daayana, S, Harrop, R et al. (2009). Immune evasion mechanisms in colorectal cancer liver metastasis patients vaccinated with TroVax (MVA-5T4). Cancer Immunol Immunother 58: 1657-1667.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 1657-1667
-
-
Elkord, E.1
Dangoor, A.2
Burt, D.J.3
Southgate, T.D.4
Daayana, S.5
Harrop, R.6
-
17
-
-
33645239282
-
Synergistic antitumor effects of immune cell-viral biotherapy
-
Thorne, SH, Negrin, RS and Contag, CH (2006). Synergistic antitumor effects of immune cell-viral biotherapy. Science 311: 1780-1784.
-
(2006)
Science
, vol.311
, pp. 1780-1784
-
-
Thorne, S.H.1
Negrin, R.S.2
Contag, C.H.3
-
18
-
-
34250735062
-
Combining immune cell and viral therapy for the treatment of cancer
-
Thorne, SH and Contag, CH (2007). Combining immune cell and viral therapy for the treatment of cancer. Cell Mol Life Sci 64: 1449-1451.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 1449-1451
-
-
Thorne, S.H.1
Contag, C.H.2
-
19
-
-
43049088485
-
Integrating the biological characteristics of oncolytic viruses and immune cells can optimize therapeutic benefits of cell-based delivery
-
Thorne, SH and Contag, CH (2008). Integrating the biological characteristics of oncolytic viruses and immune cells can optimize therapeutic benefits of cell-based delivery. Gene Ther 15: 753-758.
-
(2008)
Gene Ther
, vol.15
, pp. 753-758
-
-
Thorne, S.H.1
Contag, C.H.2
-
20
-
-
36049009021
-
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963
-
Thorne, SH, Hwang, TH, OGorman, WE, Bartlett, DL, Sei, S, Kanji, F et al. (2007). Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963. J Clin Invest 117: 3350-3358.
-
(2007)
J Clin Invest
, vol.117
, pp. 3350-3358
-
-
Thorne, S.H.1
Hwang, T.H.2
Ogorman, W.E.3
Bartlett, D.L.4
Sei, S.5
Kanji, F.6
-
21
-
-
26444543367
-
Bioluminescence imaging of vaccinia virus: Effects of interferon on viral replication and spread
-
Luker, KE, Hutchens, M, Schultz, T, Pekosz, A and Luker, GD (2005). Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread. Virology 341: 284-300.
-
(2005)
Virology
, vol.341
, pp. 284-300
-
-
Luker, K.E.1
Hutchens, M.2
Schultz, T.3
Pekosz, A.4
Luker, G.D.5
-
22
-
-
38049017526
-
Targeting of interferonbeta to produce a specific, multi-mechanistic oncolytic vaccinia virus
-
Kirn, DH, Wang, Y, Le Boeuf, F, Bell, J and Thorne, SH (2007). Targeting of interferonbeta to produce a specific, multi-mechanistic oncolytic vaccinia virus. PLoS Med 4: e353.
-
(2007)
PLoS Med
, vol.4
-
-
Kirn, D.H.1
Wang, Y.2
Le Boeuf, F.3
Bell, J.4
Thorne, S.H.5
-
23
-
-
33846900675
-
Evaluation of T cells as carriers for systemic measles virotherapy in the presence of antiviral antibodies
-
Ong, HT, Hasegawa, K, Dietz, AB, Russell, SJ and Peng, KW (2007). Evaluation of T cells as carriers for systemic measles virotherapy in the presence of antiviral antibodies. Gene Ther 14: 324-333.
-
(2007)
Gene Ther
, vol.14
, pp. 324-333
-
-
Ong, H.T.1
Hasegawa, K.2
Dietz, A.B.3
Russell, S.J.4
Peng, K.W.5
-
24
-
-
33845994768
-
Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity
-
Power, AT, Wang, J, Falls, TJ, Paterson, JM, Parato, KA, Lichty, BD et al. (2007). Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity. Mol Ther 15: 123-130.
-
(2007)
Mol Ther
, vol.15
, pp. 123-130
-
-
Power, A.T.1
Wang, J.2
Falls, T.J.3
Paterson, J.M.4
Parato, K.A.5
Lichty, B.D.6
-
25
-
-
67650375869
-
Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication
-
Prestwich, RJ, Ilett, EJ, Errington, F, Diaz, RM, Steele, LP, Kottke, T et al. (2009). Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication. Clin Cancer Res 15: 4374-4381.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4374-4381
-
-
Prestwich, R.J.1
Ilett, E.J.2
Errington, F.3
Diaz, R.M.4
Steele, L.P.5
Kottke, T.6
-
26
-
-
43049176729
-
Loading of oncolytic vesicular stomatitis virus onto antigen-specific T cells enhances the efficacy of adoptive T-cell therapy of tumors
-
Qiao, J, Wang, H, Kottke, T, Diaz, RM, Willmon, C, Hudacek, A et al. (2008). Loading of oncolytic vesicular stomatitis virus onto antigen-specific T cells enhances the efficacy of adoptive T-cell therapy of tumors. Gene Ther 15: 604-616.
-
(2008)
Gene Ther
, vol.15
, pp. 604-616
-
-
Qiao, J.1
Wang, H.2
Kottke, T.3
Diaz, R.M.4
Willmon, C.5
Hudacek, A.6
-
27
-
-
0034551730
-
Phase i study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses
-
Marshall, JL, Hoyer, RJ, Toomey, MA, Faraguna, K, Chang, P, Richmond, E et al. (2000). Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses. J Clin Oncol 18: 3964-3973.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3964-3973
-
-
Marshall, J.L.1
Hoyer, R.J.2
Toomey, M.A.3
Faraguna, K.4
Chang, P.5
Richmond, E.6
-
28
-
-
0035893770
-
Systemic cancer therapy with a tumor-selective vaccinia virus mutant lacking thymidine kinase and vaccinia growth factor genes
-
McCart, JA, Ward, JM, Lee, J, Hu, Y, Alexander, HR, Libutti, SK et al. (2001). Systemic cancer therapy with a tumor-selective vaccinia virus mutant lacking thymidine kinase and vaccinia growth factor genes. Cancer Res 61: 8751-8757.
-
(2001)
Cancer Res
, vol.61
, pp. 8751-8757
-
-
McCart, J.A.1
Ward, J.M.2
Lee, J.3
Hu, Y.4
Alexander, H.R.5
Libutti, S.K.6
-
29
-
-
0028103808
-
A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency
-
Lu, PH and Negrin, RS (1994). A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency. J Immunol 153: 1687-1696.
-
(1994)
J Immunol
, vol.153
, pp. 1687-1696
-
-
Lu, P.H.1
Negrin, R.S.2
-
30
-
-
22144494662
-
Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation
-
Cao, YA, Bachmann, MH, Beilhack, A, Yang, Y, Tanaka, M, Swijnenburg, RJ et al. (2005). Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation. Transplantation 80: 134-139.
-
(2005)
Transplantation
, vol.80
, pp. 134-139
-
-
Cao, Y.A.1
Bachmann, M.H.2
Beilhack, A.3
Yang, Y.4
Tanaka, M.5
Swijnenburg, R.J.6
-
31
-
-
0030904130
-
Green mice as a source of ubiquitous green cells
-
Okabe, M, Ikawa, M, Kominami, K, Nakanishi, T and Nishimune, Y (1997). Green mice as a source of ubiquitous green cells. FEBS Lett 407: 313-319.
-
(1997)
FEBS Lett
, vol.407
, pp. 313-319
-
-
Okabe, M.1
Ikawa, M.2
Kominami, K.3
Nakanishi, T.4
Nishimune, Y.5
-
32
-
-
3042615163
-
Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal
-
Hadjantonakis, AK, Macmaster, S and Nagy, A (2002). Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal. BMC Biotechnol 2: 11.
-
(2002)
BMC Biotechnol
, vol.2
, pp. 11
-
-
Hadjantonakis, A.K.1
MacMaster, S.2
Nagy, A.3
|