Prediction of the effects of methanol and competing ion concentration on retention in the ion chromatographic separation of anionic and cationic pharmaceutically related compounds

Journal of Chromatography A

Volumn 1217, Issue 39, 2010, Pages 6069-6076

  Zakaria, Philip ^a   Dicinoski, Greg ^a   Hanna Brown, Melissa ^b   Haddad, Paul R ^a  

^a UNIVERSITY OF TASMANIA   (Australia)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Ion chromatography prediction; Organic modifier; Organic molecules; Pharmaceutical compounds; Retention; Simulation

Indexed keywords

ORGANIC MODIFIER; ORGANIC MOLECULES; PHARMACEUTICAL COMPOUNDS; RETENTION; SIMULATION;

CHROMATOGRAPHY; CONCENTRATION (PROCESS); DIELECTRIC PROPERTIES; DYES; ERRORS; FORECASTING; HIGH PRESSURE LIQUID CHROMATOGRAPHY; ION CHROMATOGRAPHY; ION EXCHANGERS; METHANOL; POSITIVE IONS; POTASSIUM HYDROXIDE;

ION EXCHANGE;

1 NAPHTHOL; ANION; CAPTOPRIL; CATION; CHLOROTHIAZIDE; DICLOFENAC; DIPHENHYDRAMINE; DIPYRIDAMOLE; DOXEPIN; FUROSEMIDE; HYDROCORTISONE; IBUPROFEN; MESYLIC ACID; METHANOL; NAPHTHOIC ACID; PHENOL; POTASSIUM HYDROXIDE; PROPRANOLOL; SULFAMETHOXAZOLE; TOLFENAMIC ACID; TROPIC ACID; UNCLASSIFIED DRUG;

ADSORPTION; ANION EXCHANGE; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CONTROLLED STUDY; ION PAIR CHROMATOGRAPHY; PREDICTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SEPARATION TECHNIQUE;

ANIONS; CATIONS; CHROMATOGRAPHY, ION EXCHANGE; HYDROXIDES; LINEAR MODELS; MESYLATES; METHANOL; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS; POTASSIUM COMPOUNDS;

EID: 77956265692     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.07.040     Document Type: Article

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