Development and validation of method for analysis of some ototoxic solvents in saliva matrix by headspace gas chromatography/mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 26, 2010, Pages 2391-2396

  Gherardi, Monica ^a   Gordiani, Andrea ^a   Gatto, Mariapia ^a  

^a Department of Occupational Hygiene   (Italy)

Author keywords

Biological monitoring; Ototoxic solvents; Saliva matrix; Static headspace analysis

Indexed keywords

ANALYTICAL METHOD; BIOLOGICAL MONITORING; CHROMATOGRAPHIC CONDITIONS; DETERMINATION COEFFICIENTS; HEADSPACE GAS CHROMATOGRAPHY/MASS SPECTROMETRIES; HEADSPACES; HIGHLY SENSITIVE; INSTRUMENTAL PARAMETERS; INTERNAL STANDARDS; LIMIT OF DETECTION; LINEAR DYNAMIC RANGES; LOWER LIMIT OF QUANTIFICATIONS; M-XYLENE; MATRIX; METHOD VALIDATIONS; ORDERS OF MAGNITUDE; OTOTOXIC SOLVENTS; P-XYLENE; RELATIVE STANDARD DEVIATIONS; SIMULTANEOUS DETERMINATIONS; SODIUM SULPHATE; SOURCES OF UNCERTAINTY; STATIC HEADSPACE; TARGET COMPOUND; XYLENE ISOMERS;

ABSORPTION SPECTROSCOPY; AROMATIC HYDROCARBONS; BODY FLUIDS; DEUTERIUM; ETHYLBENZENE; GAS ABSORPTION; ISOMERS; MATRIX ALGEBRA; SODIUM; SPECTROMETRY; STYRENE; TERNARY SYSTEMS; TOLUENE; XYLENE;

ORGANIC SOLVENTS;

ETHYLBENZENE; META XYLENE; ORTHO XYLENE; PARA XYLENE; SODIUM SULFATE; SOLVENT; STYRENE; TOLUENE;

ACCURACY; ARTICLE; CONTROLLED STUDY; GAS CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; NORMAL HUMAN; OTOTOXICITY; PRIORITY JOURNAL; SALIVA ANALYSIS; TOXIN ANALYSIS; VALIDATION STUDY;

DRUG STABILITY; ENVIRONMENTAL MONITORING; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HAIR CELLS, AUDITORY, OUTER; HEARING DISORDERS; HUMANS; ISOMERISM; LINEAR MODELS; NOXAE; REPRODUCIBILITY OF RESULTS; SALIVA; SENSITIVITY AND SPECIFICITY; SOLVENTS; STYRENE; TEMPERATURE; XYLENES;

EID: 77956243124     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.07.007     Document Type: Article

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