A rapid radiochemical purity testing method for 99mTc-tetrofosmin

Journal of Nuclear Medicine Technology

Volumn 38, Issue 2, 2010, Pages 81-84

  Eggert, Laura A ^a   Dick, Michael D ^a   Mahoney, Douglas W ^a   Olson, Joseph P ^a   Werner, Gregory L ^a   Hung, Joseph C ^a  

^a MAYO CLINIC   (United States)

Author keywords

99mTc tetrofosmin; Nuclear pharmacy; Quality control; Radiochemical purity; Radiopharmaceutical

Indexed keywords

CHLOROFORM; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PERTECHNETIC ACID TC 99M; TETRAHYDROFURAN; TETROFOSMIN TC 99M; ORGANOPHOSPHORUS COMPOUND; TECHNETIUM COMPLEX; TECHNETIUM TC 99M 1,2 BIS(BIS(2 ETHOXYETHYL)PHOSPHINO)ETHANE; TECHNETIUM TC 99M 1,2-BIS(BIS(2-ETHOXYETHYL)PHOSPHINO)ETHANE;

ARTICLE; COMPARATIVE STUDY; RADIOCHEMICAL PURITY TESTING METHOD; RADIOCHEMISTRY; RELIABILITY; SENSITIVITY AND SPECIFICITY; CHEMISTRY; QUALITY CONTROL; REPRODUCIBILITY; STANDARD; TIME;

ORGANOPHOSPHORUS COMPOUNDS; ORGANOTECHNETIUM COMPOUNDS; QUALITY CONTROL; RADIOCHEMISTRY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TIME FACTORS;

EID: 77956222615     PISSN: 00914916     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnmt.109.070573     Document Type: Article

References (11)

1. Myoview [package insert]. Arlington Heights, IL: GE Healthcare; February 2006.
2. Technetium Tc-99m tetrofosmin injection. In: USP 32-NF27: United States Pharmacopeia and National Formulary. Rockville, MD: United States Pharmacopeial Convention; 2009:3673-3674.
3. McKay BF, Zimmer AM, Spies SM. Rapid miniaturized chromatography for technetium-99m-tetrofosmin. J Nucl Med Technol. 1997;25:52-54.
4. Hung JC, Wilson ME, Brown ML, Gibbons RJ. Rapid preparation and quality control method for technetium-99m-2-methoxy isobutyl isonitrile (technetium-99m-sestamibi). J Nucl Med. 1991;32:2162-2168.
5. Pharmaceutical compounding-sterile preparations (general chapter 797). In: USP 32-NF27: United States Pharmacopeia and National Formulary. Rockville, MD: United States Pharmacopeial Convention; 2009:319-336.
6. Kowalsky RJ, Falon SW. Radiopharmaceutical chemistry. In: Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, 2nd ed. Washington, DC: American Pharmacists Association; 2004:235-336.
7. Pandit-Taskar N, Grewal RK, Strauss HW. Cardiovascular system. In: Christian PE, Waterstram-Rich KM, eds. Nuclear Medicine and PET/CT Technology and Techniques. 6th ed. St. Louis, MO: Mosby; 2007:479-512.
8. Saha GB. Characteristics of specific radiopharmaceuticals. In: Fundamentals of Nuclear Pharmacy. 5th ed. New York, NY: Springer; 2004:111-150.
9. Hung JC, Ponto JA, Gadient KR, et al. Deficiencies of product labeling directions for the preparation of radiopharmaceuticals. J Am Pharm Assoc. 2004;44:30-35.
10. General notices and requirements. In: USP 32-NF27: United States Pharmacopeia and National Formulary. Rockville, MD: United States Pharmacopeial Convention; 2009:3-12.
11. Luebke AL, Wilary DM, Mahoney DW, Hung JC. Evaluation of an alternative radiochemical purity testing method for technetium-99m-sestamibi. J Nucl Med Technol. 2000;28:259-263.