NKG2D costimulates human Vγ9Vδ2 T cell antitumor cytotoxicity through protein kinase Cθ-dependent modulation of early TCR-induced calcium and transduction signals

Journal of Immunology

Volumn 185, Issue 1, 2010, Pages 55-63

  Nedellec, Steven ^a   Sabourin, Caroline ^a   Bonneville, Marc ^a   Scotet, Emmanuel ^a  

^a Team 12   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NATURAL KILLER CELL RECEPTOR NKG2D; PROTEIN KINASE C THETA; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; CD3 ANTIGEN; CD3 ANTIGEN, GAMMA CHAIN; CD3DELTA ANTIGEN; ISOENZYME; KLRK1 PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; PRKCQ PROTEIN, HUMAN; PROTEIN KINASE C;

ADAPTIVE IMMUNITY; ARTICLE; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; EFFECTOR CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; INNATE IMMUNITY; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL CLONE; CELL COMMUNICATION; COMPARATIVE STUDY; CYTOTOXICITY TEST; ENZYME INDUCTION; ENZYMOLOGY; EXPERIMENTAL NEOPLASM; IMMUNOLOGY; INTRACELLULAR FLUID; LYMPHOCYTE ACTIVATION; METABOLISM; METHODOLOGY; MOUSE; NATURAL KILLER T CELL; PHYSIOLOGY; T LYMPHOCYTE SUBPOPULATION; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD3; CALCIUM SIGNALING; CELL COMMUNICATION; CELL LINE, TUMOR; CLONE CELLS; CYTOTOXICITY TESTS, IMMUNOLOGIC; ENZYME INDUCTION; HUMANS; INTRACELLULAR FLUID; ISOENZYMES; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; MICE; NATURAL KILLER T-CELLS; NEOPLASMS, EXPERIMENTAL; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PROTEIN KINASE C; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS;

EID: 77956208042     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000373     Document Type: Article

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