Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Chen, Hsiang Chin ^a   Xie, Jia ^b   Zhang, Zheng ^b   Su, Li Ting ^a   Yue, Lixia ^b   Runnels, Loren W ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 5 HYDROPEROXY 6,8,11,14 ICOSATETRAENOIC ACID; 5,6 DEHYDROARACHIDONIC ACID; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 12 LIPOXYGENASE INHIBITOR; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE INHIBITOR; ARACHIDONATE 5 LIPOXYGENASE; DIVALENT CATION; DOCEBENONE; LEUKOTRIENE B4; LEUKOTRIENE D4; LIPOXYGENASE INHIBITOR; NORDIHYDROGUAIARETIC ACID; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; UNCLASSIFIED DRUG; ZILEUTON;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL STIMULATION; CELL STRAIN HEK293; CELL STRESS; CELL STRUCTURE; CELL SURFACE; CONTROLLED STUDY; ELECTRIC POTENTIAL; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN TARGETING; RNA INTERFERENCE; WHOLE CELL;

ARACHIDONATE 5-LIPOXYGENASE; BASE SEQUENCE; CELL DEATH; CELL LINE; GENE KNOCKDOWN TECHNIQUES; HUMANS; LIPOXYGENASE INHIBITORS; RNA, SMALL INTERFERING; TRPM CATION CHANNELS;

EID: 77956197489     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011161     Document Type: Article

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