Single and multidose pharmacokinetic study of a vaginal micronized progesterone insert (Endometrin) compared with vaginal gel in healthy reproductive-aged female subjects

Fertility and Sterility

Volumn 94, Issue 4, 2010, Pages 1296-1301

  Blake, Emily J ^a   Norris, Paul M ^b   Dorfman, Sally Faith ^a   Longstreth, James ^c   Yankov, Vladimir I ^a  

^a Ferring Pharmaceuticals Inc USA   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Longstreth and Associates Inc   (United States)

Author keywords

assisted reproductive technology; Endometrin; in vitro fertilization; IVF; luteal support; pharmacokinetics; PK; progesterone; progesterone supplementation; vaginal

Indexed keywords

ENDOMETRIN; PROGESTERONE; UNCLASSIFIED DRUG; AGENTS USED INTRAVAGINALLY; DRUG DOSAGE FORM;

ABDOMINAL PAIN; ADULT; AREA UNDER THE CURVE; ARTICLE; BACKACHE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG CLEARANCE; FEMALE; GEL; HUMAN; INFERTILITY THERAPY; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; OPEN STUDY; PARALLEL DESIGN; PATIENT COMPLIANCE; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; RASH; STEADY STATE; TREATMENT DURATION; TREATMENT RESPONSE; VAGINA BLEEDING; ADOLESCENT; AGE; BLOOD; COMPARATIVE STUDY; DRUG ADMINISTRATION; DRUG DOSAGE FORM; DRUG EFFECTS; HEALTH; INTRAVAGINAL DRUG ADMINISTRATION; PHYSIOLOGY; REPRODUCTION; TIME; YOUNG ADULT;

ADMINISTRATION, INTRAVAGINAL; ADOLESCENT; ADULT; AGE FACTORS; DOSAGE FORMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEALTH; HUMANS; PROGESTERONE; REPRODUCTION; REPRODUCTIVE TECHNIQUES, ASSISTED; TIME FACTORS; VAGINAL CREAMS, FOAMS, AND JELLIES; YOUNG ADULT;

EID: 77956188164     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2009.06.014     Document Type: Article

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