Candida albicans SH3-domain proteins involved in hyphal growth, cytokinesis, and vacuolar morphology

Current Genetics

Volumn 56, Issue 4, 2010, Pages 309-319

  Reijnst, Patrick ^a   Jorde, Sigyn ^a   Wendland, Jürgen ^a  

^a CARLSBERG LABORATORY   (Denmark)

Author keywords

Actin cytoskeleton; Candida albicans; FM4 64; PCR based gene targeting; pFA plasmids

Indexed keywords

FUNGAL PROTEIN; GREEN FLUORESCENT PROTEIN; PROTEIN CYK3; PROTEIN NBP2; PROTEIN SH3; PROTEIN SLA1; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOKINESIS; ENDOCYTOSIS; FUNGAL GENE; FUNGAL MORPHOLOGY; FUNGAL STRAIN; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS MUTANT; GENE DELETION; GENE LOCATION; GENETIC ANALYSIS; GERM CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; WILD TYPE; CELL VACUOLE; CHEMISTRY; GENETICS; GROWTH, DEVELOPMENT AND AGING; PHYSIOLOGY; SRC HOMOLOGY DOMAIN; ULTRASTRUCTURE;

CANDIDA ALBICANS; CYTOKINESIS; FUNGAL PROTEINS; HYPHAE; SRC HOMOLOGY DOMAINS; VACUOLES;

CANDIDA ALBICANS; SACCHAROMYCES CEREVISIAE;

EID: 77956188139     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00294-010-0301-7     Document Type: Article

References (40)

1. MS am Busch D Mignon T Simonson 2009 Computational protein design as a tool for fold recognition Proteins 77 139 158 10.1002/prot.22426 19408297
2. CJ Barelle ML Richard C Gaillardin NA Gow AJ Brown 2006 Candida albicans VAC8 is required for vacuolar inheritance and normal hyphal branching Eukaryot Cell 5 359 367 10.1128/EC.5.2.359-367.2006 1:CAS:528:DC%2BD28Xhslartrg%3D 16467476
3. M Bassilana J Blyth RA Arkowitz 2003 Cdc24, the GDP-GTP exchange factor for Cdc42, is required for invasive hyphal growth of Candida albicans Eukaryot Cell 2 9 18 10.1128/EC.2.1.9-18.2003 1:CAS:528:DC%2BD3sXhtlOmu7g%3D 12582118
4. J Bauer J Wendland 2007 Candida albicans Sfl1 suppresses flocculation and filamentation Eukaryot Cell 6 1736 1744 10.1128/EC.00236-07 1:CAS:528:DC%2BD2sXht1Smu73L 17766464
5. J Berman PE Sudbery 2002 Candida albicans: a molecular revolution built on lessons from budding yeast Nat Rev Genet 3 918 930 10.1038/nrg948 1:CAS:528:DC%2BD38XptFCjt74%3D 12459722
6. RA Calderone WA Fonzi 2001 Virulence factors of Candida albicans Trends Microbiol 9 327 335 10.1016/S0966-842X(01)02094-7 1:CAS:528:DC%2BD3MXlsFKntr0%3D 11435107
7. RS Care J Trevethick KM Binley PE Sudbery 1999 The MET3 promoter: a new tool for Candida albicans molecular genetics Mol Microbiol 34 792 798 10.1046/j.1365-2958.1999.01641.x 1:CAS:528:DyaK1MXnslyjsb0%3D 10564518
8. H Court P Sudbery 2007 Regulation of Cdc42 GTPase activity in the formation of hyphae in Candida albicans Mol Biol Cell 18 265 281 10.1091/mbc.E06-05-0411 1:CAS:528:DC%2BD2sXmsFymtA%3D%3D 17093060
9. B Enloe A Diamond AP Mitchell 2000 A single-transformation gene function test in diploid Candida albicans J Bacteriol 182 5730 5736 10.1128/JB.182.20. 5730-5736.2000 1:CAS:528:DC%2BD3cXnt1aisrk%3D 11004171
10. JA Epp J Chant 1997 An IQGAP-related protein controls actin-ring formation and cytokinesis in yeast Curr Biol 7 921 929 10.1016/S0960-9822(06) 00411-8 1:CAS:528:DyaK2sXotFSnu7k%3D 9382845
11. AM Gillum EY Tsay DR Kirsch 1984 Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations Mol Gen Genet 198 179 182 10.1007/BF00328721 1:CAS:528:DyaL2MXhsl2qurk%3D 6394964
12. S Gola R Martin A Walther A Dunkler J Wendland 2003 New modules for PCR-based gene targeting in Candida albicans: rapid and efficient gene targeting using 100 bp of flanking homology region Yeast 20 1339 1347 10.1002/yea.1044 1:CAS:528:DC%2BD2cXhtVGksQ%3D%3D 14663826
13. S Karkkainen M Hiipakka JH Wang I Kleino M Vaha-Jaakkola GH Renkema M Liss R Wagner K Saksela 2006 Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome EMBO Rep 7 186 191 10.1038/sj.embor.7400596 16374509
14. WS Korinek E Bi JA Epp L Wang J Ho J Chant 2000 Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast Curr Biol 10 947 950 10.1016/S0960- 9822(00)00626-6 1:CAS:528:DC%2BD3cXlsFCmtbk%3D 10959846
15. CA Kumamoto MD Vinces 2005 Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulence Cell Microbiol 7 1546 1554 10.1111/j.1462-5822.2005.00616.x 1:CAS:528:DC%2BD2MXhtFGkt7vP 16207242
16. R Martin D Hellwig Y Schaub J Bauer A Walther J Wendland 2007 Functional analysis of Candida albicans genes whose Saccharomyces cerevisiae homologues are involved in endocytosis Yeast 24 511 522 10.1002/yea.1489 1:CAS:528: DC%2BD2sXntl2hsL8%3D 17431925
17. BJ Mayer 2001 SH3 domains: complexity in moderation J Cell Sci 114 1253 1263 1:CAS:528:DC%2BD3MXjt1Omt7k%3D 11256992
18. S Michel S Ushinsky B Klebl E Leberer D Thomas M Whiteway J Morschhauser 2002 Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes Mol Microbiol 46 269 280 10.1046/j.1365-2958.2002. 03167.x 1:CAS:528:DC%2BD38XotFShsL4%3D 12366849
19. CJ Nobile AP Mitchell 2009 Large-scale gene disruption using the UAU1 cassette Methods Mol Biol 499 175 194 10.1007/978-1-60327-151-6-17 1:CAS:528:DC%2BD1MXjsF2jtb8%3D 19152049
20. SM Noble AD Johnson 2005 Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans Eukaryot Cell 4 298 309 10.1128/EC.4.2.298-309.2005 1:CAS:528:DC%2BD2MXitVWmu7Y%3D 15701792
21. U Oberholzer A Marcil E Leberer DY Thomas M Whiteway 2002 Myosin I is required for hypha formation in Candida albicans Eukaryot Cell 1 213 228 10.1128/EC.1.2.213-228.2002 1:CAS:528:DC%2BD38XjtVOisL0%3D 12455956
22. FC Odds 1994 Pathogenesis of Candida infections J Am Acad Dermatol 31 S2 S5 10.1016/S0190-9622(08)81257-1 1:STN:280:DyaK2czlvVansA%3D%3D 8077502
23. K Ohkuni A Okuda A Kikuchi 2003 Yeast Nap1-binding protein Nbp2p is required for mitotic growth at high temperatures and for cell wall integrity Genetics 165 517 529 1:CAS:528:DC%2BD3sXpt1Omu7c%3D 14573466
24. D Pruyne A Bretscher 2000 Polarization of cell growth in yeast J Cell Sci 113 571 585 1:CAS:528:DC%2BD3cXhvFSgsbc%3D 10652251
25. D Pruyne A Bretscher 2000 Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states J Cell Sci 113 365 375 1:CAS:528:DC%2BD3cXhsFCqsL8%3D 10639324
26. Y Schaub A Dunkler A Walther J Wendland 2006 New pFA-cassettes for PCR-based gene manipulation in Candida albicans J Basic Microbiol 46 416 429 10.1002/jobm.200510133 1:CAS:528:DC%2BD28Xht1Sqs7jK 17009297
27. P Sudbery N Gow J Berman 2004 The distinct morphogenic states of Candida albicans Trends Microbiol 12 317 324 10.1016/j.tim.2004.05.008 1:CAS:528:DC%2BD2cXlt1ansbc%3D 15223059
28. HY Tang J Xu M Cai 2000 Pan1p, End3p, and S1a1p, three yeast proteins required for normal cortical actin cytoskeleton organization, associate with each other and play essential roles in cell wall morphogenesis Mol Cell Biol 20 12 25 10.1128/MCB.20.1.12-25.2000 1:CAS:528:DC%2BD3cXltFyq 10594004
29. V Veses NA Gow 2008 Vacuolar dynamics during the morphogenetic transition in Candida albicans FEMS Yeast Res 8 1339 1348 10.1111/j.1567-1364.2008.00447.x 1:CAS:528:DC%2BD1cXhsVCjt7jJ 19054134
30. V Veses A Richards NA Gow 2009 Vacuole inheritance regulates cell size and branching frequency of Candida albicans hyphae Mol Microbiol 71 505 519 10.1111/j.1365-2958.2008.06545.x 1:CAS:528:DC%2BD1MXhs1Oisbs%3D 19040629
31. A Walther J Wendland 2003 An improved transformation protocol for the human fungal pathogen Candida albicans Curr Genet 42 339 343 10.1007/s00294-002-0349-0 1:CAS:528:DC%2BD3sXhsFKqu7k%3D 12612807
32. A Walther J Wendland 2004 Apical localization of actin patches and vacuolar dynamics in Ashbya gossypii depend on the WASP homolog Wal1p J Cell Sci 117 4947 4958 10.1242/jcs.01377 1:CAS:528:DC%2BD2cXhtVSns7vP 15367585
33. A Walther J Wendland 2004 Polarized hyphal growth in Candida albicans requires the Wiskott-Aldrich Syndrome protein homolog Wal1p Eukaryot Cell 3 471 482 10.1128/EC.3.2.471-482.2004 1:CAS:528:DC%2BD2cXjtlKqs74%3D 15075276
34. A Walther J Wendland 2008 PCR-based gene targeting in Candida albicans Nat Protoc 3 1414 1421 10.1038/nprot.2008.137 1:CAS:528:DC%2BD1cXhtVOns7fJ 18772868
35. DT Warren PD Andrews CW Gourlay KR Ayscough 2002 Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics J Cell Sci 115 1703 1715 1:CAS:528:DC%2BD38XjslWiu7g%3D 11950888
36. LS Weisman R Bacallao W Wickner 1987 Multiple methods of visualizing the yeast vacuole permit evaluation of its morphology and inheritance during the cell cycle J Cell Biol 105 1539 1547 10.1083/jcb.105.4.1539 1:STN:280: DyaL1c%2Fjtlahtg%3D%3D 2444598
37. J Wendland 2001 Comparison of morphogenetic networks of filamentous fungi and yeast Fungal Genet Biol 34 63 82 10.1006/fgbi.2001.1290 1:CAS:528:DC%2BD3MXnvFWlsbY%3D 11686673
38. J Wendland P Philippsen 2002 An IQGAP-related protein, encoded by AgCYK1, is required for septation in the filamentous fungus Ashbya gossypii Fungal Genet Biol 37 81 88 10.1016/S1087-1845(02)00034-8 1:CAS:528:DC%2BD38Xms1yrsbk%3D 12223192
39. EA Winzeler DD Shoemaker A Astromoff H Liang K Anderson B Andre R Bangham R Benito JD Boeke H Bussey AM Chu C Connelly K Davis F Dietrich SW Dow M El Bakkoury F Foury SH Friend E Gentalen G Giaever JH Hegemann T Jones M Laub H Liao N Liebundguth DJ Lockhart A Lucau-Danila M Lussier N M'Rabet P Menard M Mittmann C Pai C Rebischung JL Revuelta L Riles CJ Roberts P Ross-MacDonald B Scherens M Snyder S Sookhai-Mahadeo RK Storms S Veronneau M Voet G Volckaert TR Ward R Wysocki GS Yen K Yu K Zimmermann P Philippsen M Johnston RW Davis 1999 Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis Science 285 901 906 10.1126/science.285.5429.901 1:CAS:528:DyaK1MXltVelsbo%3D 10436161
40. XD Zheng RT Lee YM Wang QS Lin Y Wang 2007 Phosphorylation of Rga2, a Cdc42 GAP, by CDK/Hgc1 is crucial for Candida albicans hyphal growth EMBO J 26 3760 3769 10.1038/sj.emboj.7601814 1:CAS:528:DC%2BD2sXptlSqsbw%3D 17673907