Retrospective study on temporal and regional variations of methylmercury concentrations in preserved umbilical cords collected from inhabitants of the Minamata area, Japan

Ecotoxicology and Environmental Safety

Volumn 73, Issue 6, 2010, Pages 1144-1149

  Sakamoto, Mineshi ^a   Murata, Katsuyuki ^b   Tsuruta, Kazuhito ^c   Miyamoto, Kenichiro ^a   Akagi, Hirokatsu ^d  

^a NATIONAL INSTITUTE FOR MINAMATA DISEASE   (Japan)

^b AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Junwakai Memorial Hospital   (Japan)

^d International Mercury Laboratory   (Japan)

Author keywords

Methylmercury exposure; Minamata disease; Preserved cord tissue; Regional distribution; Time course distribution

Indexed keywords

ACETALDEHYDE; METHYLMERCURY;

ACETALDEHYDE; CONCENTRATION (COMPOSITION); METHYLMERCURY; POLLUTION EXPOSURE; SPATIAL DISTRIBUTION; TEMPORAL VARIATION;

ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; JAPAN; MAJOR CLINICAL STUDY; MALE; MINAMATA DISEASE; POLLUTION; RETROSPECTIVE STUDY; UMBILICAL CORD;

CASE-CONTROL STUDIES; CHEMICAL INDUSTRY; CITIES; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; JAPAN; MALE; MERCURY POISONING, NERVOUS SYSTEM; METHYLMERCURY COMPOUNDS; RETROSPECTIVE STUDIES; TIME FACTORS; TISSUE DISTRIBUTION; UMBILICAL CORD; WATER POLLUTANTS, CHEMICAL;

AKITA; CHUBU; CHUGOKU; FUKUI; FUKUOKA [KYUSHU]; HONSHU; IZUMI; JAPAN; KANTO; KUMAMOTO; KYUSHU; MINAMATA; MIYAZAKI; NAGASAKI [KYUSHU]; TOHOKU; TOKYO [KANTO]; TOTTORI [CHUGOKU]; TOTTORI [TOTTORI (PRF)]; TSUSHIMA;

EID: 77956187691     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2010.05.007     Document Type: Article

References (21)

1. Akagi H., Castillo E.S., Cortes-Maramba N., Francisco-Rivera A.T., Timbang T.D. Health assessment for mercury exposure among schoolchildren residing near a gold processing and refining plant in Apokon, Tagum, Davao del Norte, Philippines. Sci. Total Environ. 2000, 259:31-43.
2. Akagi H., Grandjean P., Takizawa Y., Weihe P. Methylmercury dose estimation from umbilical cord concentrations in patients with Minamata disease. Environ. Res. 1998, 77:98-103.
3. Choi B.H. Effects of methylmercury on the developing brain. Prog. Neurobiol. 1989, 32:447-470.
4. Grandjean P., Budtz-Jorgensen E., Jorgensen P.J., Weihe P. Umbilical cord mercury concentration as biomarker of prenatal exposure to methylmercury. Environ. Health Perspect. 2005, 113:905-908.
5. Harada M., Akagi H., Tsuda T., Kizaki T., Ohno H. Methylmercury level in umbilical cords from patients with congenital Minamata disease. Sci. Total Environ. 1999, 234:59-62.
6. Harada M., Yorifuji T. Methylmercury level in umbilical cords from inhabitants in Shiranuhi district. Journal of Minamata Studies 2009, 1:151-167. (in Japanese).
7. Harada Y. Congenital (or fetal) Minamata disease. Minamata Dis. 1968, 93-118.
8. Horvat M., Liang L., Azemard S., Mandić V., Villeneuve J.P., Coquery M. Certification of total mercury and methylmercury concentrations in mussel homogenate (Mytilus edulis) reference material, IAEA-142. Fresenius J. Anal. Chem. 1997, 358:411-418.
9. Irukayama K., Kondo T., Kai F., Fujiki M., Tajima S. An organomercury compound extracted from sludge at the acetaldehyde plant of the Minamata factory. Nisshin Igaku Jpn. J. Med. Prog. 1962, 49:536-541.
10. Kitamura S. Determination on mercury content in bodies of inhabitants, cats, fishes and shells in Minamata district and in mud of Minamata Bay. Minamata Dis. 1968, 331-345.
11. Murata K., Sakamoto M., Nakai K., Iwata T., Liu X.J., Satoh H. Subclinical effects of prenatal methylmercury exposure on autonomic function in Japanese children. Int Arch Occup. Environ Health 2006, 79:379-386.
12. Nishigaki S., Harada M. Methylmercury and selenium in umbilical cords of inhabitants of the Minamata area. Nature 1975, 258:324-325.
13. NRC National Research Council (USA). Toxicological Effects of Methylmercury 2000, National Academy Press, Washington, DC.
14. Sakamoto M., Kakita A., Wakabayashi K., Takahashi H., Nakano A., Akagi H. Evaluation of changes in methylmercury accumulation in the developing rat brain and its effects: a study with consecutive and moderate dose exposure throughout gestation and lactation periods. Brain Res. 2002, 949:51-59.
15. Sakamoto M., Kaneoka T., Murata K., Nakai K., Satoh H., Akagi H. Correlations between mercury concentrations in umbilical cord tissue and other biomarkers of fetal exposure to methylmercury in the Japanese population. Environ. Res. 2007, 103:106-111.
16. Sakamoto M., Kubota M., Matsumoto S., Nakano A., Akagi H. Declining risk of methylmercury exposure to infants during lactation. Environ. Res. 2002, 90:185-189.
17. Sakamoto M., Kubota M., Liu X.J., Murata K., Nakai H., Satoh H. Maternal and fetal mercury and n-3 polyunsaturated fatty acids as a risk and benefit of fish consumption to fetus. Environ. Sci. Technol. 2004, 38:3860-3863.
18. Stern A.H., Smith A.E An assessment of the cord blood: maternal blood methylmercury ratio: implications for risk assessment. Environ. Health Perspect. 2003, 111:1465-1470.
19. WHO Methylmercury. In: Environmental Health Criteria, vol.101 1990, World Health Organization, Geneva.
20. Westoo G. Determination of methylmercury salts in various kinds of biological material. Acta Chem. Scand. 1968, 22:2277-2280.
21. Yasutake A., Matsumoto M., Yamaguchi M., Hachiya N. Current hair mercury levels in Japanese: survey in five districts. Tohoku J. Exp. Med. 2003, 199:161-169.