Synthesis and structure-activity relationships of sinenxan A derivatives as multidrug resistance reversal agents

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 18, 2010, Pages 5418-5421

  Huang, Meng ^a,b   Zhao, Xin ^a   Zhang, Meng ^a   Gu, Jun ^a   Chen, Xiaoguang ^a   Yin, Dali ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Anti cancer; Multidrug resistant reversal activity; Sinenxan A derivatives

Indexed keywords

ANTINEOPLASTIC AGENT; CARBONYL DERIVATIVE; SINENXAN A DERIVATIVE; TAXEZOPIDINE G; TAXININE; UNCLASSIFIED DRUG; VERAPAMIL;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MULTIDRUG RESISTANCE; STRUCTURE ACTIVITY RELATION;

ACETATES; CALCIUM CHANNEL BLOCKERS; DITERPENES; DRUG RESISTANCE, MULTIPLE; HUMANS; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; TAXUS; TUMOR CELLS, CULTURED; VERAPAMIL;

EID: 77956178823     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.07.099     Document Type: Article

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