The inhibitory potency of SCH 23390 and raclopride on licking for sucrose increases across brief-access tests

Physiology and Behavior

Volumn 101, Issue 3, 2010, Pages 315-319

  Smith, Gerard P ^a   Smith, James C ^b  

^a NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^b FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Dopamine; Dopamine antagonists; Food reward; Incentive motivation; Licking; Nucleus accumbens; Orosensory control of intake; Orosensory positive feedback; Raclopride; SCH 23390; Sweet taste; Sweet taste reward

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; PIMOZIDE; RACLOPRIDE; SACCHARIN; SUCROSE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DRUG POTENCY; LATENT PERIOD; LICKING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUGAR INTAKE; SWEETNESS;

ANALYSIS OF VARIANCE; ANIMALS; BENZAZEPINES; CONDITIONING, CLASSICAL; DOPAMINE ANTAGONISTS; DRINKING BEHAVIOR; EATING; INHIBITION (PSYCHOLOGY); MALE; RACLOPRIDE; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; REWARD; SUCROSE; TASTE; TIME FACTORS;

EID: 77956176067     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2010.05.013     Document Type: Article

References (25)

1. Wise R.A., Spindler J., Legault L. Major attenuation of food reward with performance-sparing doses of pimozide in the rat. Can J Psychol 1978, 32(2):77-85.
2. Gramling S.E., Fowler S.C., Collins K.R. Some effects of pimozide on nondeprived rats licking sucrose solutions in an anhedonia paradigm. Pharmacol Biochem Behav 1984, 21(4):617-624.
3. Gramling S.E., Fowler S.C., Tizzano J.P. Some effects of pimozide on nondeprived rats' lever pressing maintained by a sucrose reward in an anhedonia paradigm. Pharmacol Biochem Behav 1987, 27(1):67-72.
4. Smith J.C., Davis J.D., O'Keefe G.B. Lack of an order effect in brief contact taste tests with closely spaced test trials. Physiol Behav 1992, 52(6):1107-1111.
5. Smith J.C. The history of the "Davis Rig". Appetite 2001, 36(1):93-98.
6. Pfaffmann C. Taste: a model of incentive motivation. The physiological mechanisms of motivation 1982, 61-98. Springer, New York. D. Pfaff (Ed.).
7. Cannon C.M., Palmiter R.D. Reward without dopamine. J Neurosci 2003, 23(34):10827-10831.
8. Palmiter R.D. Dopamine signaling in the dorsal striatum is essential for motivated behaviors: lessons from dopamine-deficient mice. Ann N Y Acad Sci 2008, 1129:35-46.
9. Xenakis S., Sclafani A. The effects of pimozide on the consumption of a palatable saccharin-glucose solution in the rat. Pharmacol Biochem Behav 1981, 15(3):435-442.
10. Geary N., Smith G.P. Pimozide decreases the positive reinforcing effect of sham fed sucrose in the rat. Pharmacol Biochem Behav 1985, 22(5):787-790.
11. Schneider L.H., Gibbs J., Smith G.P. D-2 selective receptor antagonists suppress sucrose sham feeding in the rat. Brain Res Bull 1986, 17(4):605-611.
12. Schneider L., Greenberg D., Smith G.P. Comparison of the effects of selective D-1 and D-2 receptor antagonists on sucrose sham feeding and water sham drinking. The mesocorticolimbic dopamine system 1988, 534-537. New York Academy of Sciences, New York. P.W. Kalivas, C.B. Nemeroff (Eds.).
13. Schneider L.H. Orosensory self-stimulation by sucrose involves brain dopaminergic mechanisms. Ann N Y Acad Sci 1989, 575:307-319.
14. Schneider L.H., Davis J.D., Watson C.A., Smith G.P. Similar effect of raclopride and reduced sucrose concentration on the microstructure of sucrose sham feeding. Eur J Pharmacol 1990, 186(1):61-70.
15. Duong A., Weingarten H.P. Dopamine antagonists act on central, but not peripheral, receptors to inhibit sham and real feeding. Physiol Behav 1993, 54(3):449-454.
16. Hajnal A., Smith G.P., Norgren R. Oral sucrose stimulation increases accumbens dopamine in the rat. Am J Physiol Regul Integr Comp Physiol 2004, 286(1):R31-R37.
17. Mark G., Blander D., Hoebel B. A conditioned stimulus decreases extracellular dopamine in the nucleus accumbens after the development of a learned taste aversion. Brain Res 1991, 551:308-310.
18. Hajnal A., Norgren R. Accumbens dopamine mechanisms in sucrose intake. Brain Res 2001, 904(1):76-84.
19. Rhinehart-Doty J.A., Schumm J., Smith J.C., Smith G.P. A non-taste cue of sucrose in short-term taste tests in rats. Chem Senses 1994, 19(5):425-431.
20. Walker H.M., Lev J. Statistical inference 1953, Henry Holt and Co., New York.
21. Wise R.A., Colle L.M. Pimozide attenuates free feeding: best scores analysis reveals a motivational deficit. Psychopharmacology (Berl) 1984, 84(4):446-451.
22. Wise R.A., Raptis L. Effects of naloxone and pimozide on initiation and maintenance measures of free feeding. Brain Res 1986, 368(1):62-68.
23. Koechling G., Colle L.M., Wise R.A. Effects of SCH 23390 on motivational aspects of deprivation-induced feeding. Psychobiology 1988, 16:207-212.
24. Tombaugh T.N., Tombaugh J., Anisman H. Effects of dopamine receptor blockade on alimentary behaviors: home cage food consumption, magazine training, operant acquisition, and performance. Psychopharmacology (Berl) 1979, 66(3):219-225.
25. Tombaugh T.N., Szostak C., Voorneveld P., Tombaugh J.W. Failure to obtain functional equivalence between dopamine receptor blockade and extinction: evidence supporting a sensory-motor conditioning hypothesis. Pharmacol Biochem Behav 1982, 16(1):67-72.